Results 91 to 100 of about 11,200 (227)

Clinical Trial Protocol for Porcine Islet Xenotransplantation in South Korea [PDF]

Diabetes & Metabolism Journal
Background Islet transplantation holds promise for treating selected type 1 diabetes mellitus patients, yet the scarcity of human donor organs impedes widespread adoption.
Byung-Joon Kim, Jun-Seop Shin, Byoung-Hoon Min, Jong-Min Kim, Chung-Gyu Park, Hee-Jung Kang, Eung Soo Hwang, Won-Woo Lee, Jung-Sik Kim, Hyun Je Kim, Iov Kwon, Jae Sung Kim, Geun Soo Kim, Joonho Moon, Du Yeon Shin, Bumrae Cho, Heung-Mo Yang, Sung Joo Kim, Kwang-Won Kim   +18 more
doaj   +1 more source

Expression and function of alpha(v)beta(3) and alpha(v)beta(5) integrins in the developing pancreas: roles in the adhesion and migration of putative endocrine progenitor cells. [PDF]

, 2000
Cell-cell and cell-matrix interactions play a critical role in tissue morphogenesis and in homeostasis of adult tissues. The integrin family of adhesion receptors regulates cellular interactions with the extracellular matrix, which provides three ...
Alpert, Bauer, Beattie, Beattie, Beattie, Blaschuk, Bosco, Brooks, Brooks, Calof, Cheng, Choquet, Cirulli, Cirulli, Cirulli, Clark, Clark, Dahl, DiPersio, Drake, Dudek, Ekblom, Felding-Habermann, Friedlander, George, Giancotti, Gu, Gu, Gullberg, Herrera, Herrera, Hynes, Hynes, Jaffe, Jansson, Jensen, Jones, Kantengwa, Langerhans, Langhofer, Like, Lin, Lombardi, Marchisio, Orci, Orci, Orci, Otonkoski, Otonkoski, Otonkoski, Pelletier, Pictet, Pictet, Pierschbacher, Ricordi, Rouiller, Sandler, Schwartz, Slack, Sonnenberg, Stefan, Strange, Talhouk, Teitelman, Tuch, Von Dorsche, Walker, Watt   +67 more
core   +1 more source

Outcome of human islet isolation and allotransplantation in 20 consecutive cases. [PDF]

, 1992
This report provides our initial experience on islet isolation and intrahepatic allotransplantation in 20 patients. In Group 1, 10 patients underwent combined liver-islet allotransplantation following upper-abdominal exenteration for cancer.
Alejandro, R, Carroll, P, Demetris, AJ, Fung, JJ, Mintz, DH, Ricordi, C, Rilo, HLR, Shapiro, R, Starzl, TE, Tzakis, A, Zeng, Y   +10 more
core  

Comparative efficacy of Belzer or Euro-Collins solutions for pancreatic preservation during cold ischemic storage in rats [PDF]

, 2014
PURPOSE:To compare the efficacy of different types of solutions (Belzer or Euro-Collins) for the preservation of rat pancreas during cold ischemia. METHODS:Thirty Wistar rats were divided into three groups according to the perfusion or storage solution ...
Goldenberg, Alberto, Gonzalez, Adriano Miziara, Netto, Alcides Augusto Salzedas, Perez, Rogerio Renato   +3 more
core   +3 more sources

The liver surface as a favorable site for islet cell sheet transplantation in type 1 diabetes model mice [PDF]

, 2018
Introduction: Islet transplantation is one of the most promising therapeutic approaches for patients with severe type 1 diabetes mellitus (T1DM). Transplantation of engineered islet cell sheets holds great potential for treating T1DM as it enables the ...
Fujita Izumi, Okano Teruo, Utoh Rie, Yamamoto Masakazu, Yamato Masayuki   +4 more
core   +3 more sources

The pancreas anatomy conditions the origin and properties of resident macrophages [PDF]

, 2015
We examine the features, origin, turnover, and gene expression of pancreatic macrophages under steady state. The data distinguish macrophages within distinct intrapancreatic microenvironments and suggest how macrophage phenotype is imprinted by the local
Ajami, Bain, Banaei-Bouchareb, Boris Calderon, Boyer, Boyer, Buza-Vidas, Böiers, Calderon, Calderon, Carrero, Chu, Clark, Cucak, DeFalco, Dorothy K. Sojka, Ehses, Emil R. Unanue, Epelman, Epelman, Ferrante, Ferris, Gautier, Geutskens, Ginhoux, Gordon, Gosselin, Guilliams, Gwendalyn J. Randolph, Haniffa, Hashimoto, Hoeffel, Hume, Ino, Javier A. Carrero, Kenneth M. Murphy, Kumaravelu, Lavin, Lewis, Li, Lichanska, Lichanska, Lin, Lindsay Moore, Lumeng, Melli, Merad, Meredith, Mohan, Molawi, Murray, Murray, Peng, Pinto, Pollard, Richardson, Salvalaggio, Satpathy, Satpathy, Schulz, Serbina, Shaul, Sica, Slava Epelman, Sojka, Spits, Stephen T. Ferris, Wang, Wayne M. Yokoyama, Westwell-Roper, Xiao, Yin, Yona   +72 more
core   +2 more sources

Regulation of the JNK3 signaling pathway during islet isolation: JNK3 and c-fos as new markers of islet quality for transplantation. [PDF]

, 2014
Stress conditions generated throughout pancreatic islet processing initiate the activation of pro-inflammatory pathways and beta-cell destruction. Our goal is to identify relevant and preferably beta-specific markers to assess the activation of beta-cell
A Caumo, A Fornoni, A Ilieva, AF Ziolkowski, AJ Whitmarsh, AM Shapiro, AM Shapiro, AM Shapiro, Amar Abderrahmani, B Nilsson, Bernhard J. Hering, BJ Hering, C Bonny, C Fraker, C Ricordi, C Ricordi, C Ricordi, Christophe Bonny, CN Street, DP Brazil, DS Kim, E Shaulian, F Bertuzzi, GA Keesler, H Cho, H Cho, IR Sweet, J Mellert, J Yasuda, Kate R. Mueller, KK Papas, KK Papas, KK Papas, KK Papas, KK Papas, Klearchos K. Papas, KR Mueller, L Rosenberg, M Goto, M Nagata, Mike P. Murtaugh, RJ Davis, RN Wang, S Abdelli, S Abdelli, S Abdelli, S Abdelli, S Estus, S Goto, S Paraskevas, S Paraskevas, S Srinivasan, S Susini, S Zhang, Saida Abdelli, T Froud, TM Suszynski   +56 more
core   +2 more sources

Isolation, banking, encapsulation and transplantation of different types of Langerhans islets

Polish Archives of Internal Medicine, 2009
The discovery of a cure for diabetes is a dream of many medical researchers. The transplantation of Langerhans islets is a potential treatment of choice for patients with type 1 diabetes as a source of endogenous insulin for the recipient.The aim of the experiment was to transplant Langerhans islets without immunosuppression.
Magdalena, Antosiak-Iwańska, Elzbieta, Sitarek, Marek, Sabat, Ewa, Godlewska, Joanna, Kinasiewicz, Andrzej, Weryński   +5 more
openaire   +2 more sources

Long‐term efficacy of encapsulated xenogeneic islet transplantation: Impact of encapsulation techniques and donor genetic traits

Journal of Diabetes Investigation
Aims/Introduction To investigate the long‐term efficacy of various encapsulated xenogeneic islet transplantation, and to explore the impact of different donor porcine genetic traits on islet transplantation outcomes.
Heon‐Seok Park, Eun Young Lee, Young‐Hye You, Marie Rhee, Jong‐Min Kim, Seong‐Soo Hwang, Poong‐Yeon Lee   +6 more
doaj   +1 more source

Gelatin Density Gradient for Isolation of Islets of Langerhans

Cell Transplantation, 1998
Isolation of islets of Langerhans (islets) has been performed by means of collagenase digestion of the pancreatic tissue combined with density gradient separation of islets from unwanted exocrine tissues.
Tadashi Samejima, Kenji Yamaguchi, Hiroo Iwata, Noriyuki Morikawa, Yoshito Ikada   +4 more
doaj   +1 more source