Polo‐like kinases and UV‐induced skin carcinogenesis: What we know and what's next
The polo‐like kinase (PLK) family plays distinct and critical roles in the regulation of cell cycle progression, and its dysregulation has been implicated in various cancers. Ultraviolet (UV) radiation is a well‐established environmental factor in the development of skin cancer.
Tanya Jaiswal +3 more
wiley +1 more source
Phylogeny, systematics and evolution of mimicry patterns in Neotropical limenitidine butterflies
The most comprehensive phylogeny for Adelpha reveals that it is not monophyletic, supporting the description of the new genus Adelphina for the alala‐group. The rate of mimicry evolution increases towards the tropics, consistent with the hypothesis of stronger biotic interactions near the equator.
Erika Páez V. +17 more
wiley +1 more source
Optic Chiasm and Bilateral Optic Nerve Oligodendroglioma in A 29‐Month‐Old German Shepherd
ABSTRACT Objective To report the first documented case of high‐grade optic chiasm and nerve oligodendroglioma in a young dog and contribute to the comparative study of gliomas in humans and canines. Animal Studied A 29‐month‐old male intact German Shepherd.
Vienna M. Lunking +7 more
wiley +1 more source
Abstract figure legend Sprint interval training (SIT) is a popular time‐efficient type of endurance training. Healthy young men performed nine SIT sessions (4–6 × 30 s all‐out cycling sprints) over 3 weeks while being supplemented with antioxidants (high doses of vitamins C and E) or placebo. Muscle biopsies taken before and after the first SIT session
Victoria L. Wyckelsma +12 more
wiley +1 more source
Therapeutic targeting of chromatin alterations in leukemia and solid tumors
Abstract Alterations in chromatin conformation and post‐translational modification of histones have become increasingly recognized as critical drivers of cancer development, progression, and therapy resistance. Recent advances in drug development have led to the establishment of several highly selective small molecule inhibitors, several of which are ...
Florian Perner +7 more
wiley +1 more source
Biosynthesis Of Glyoxysomal Enzymes In Neurospora Crassa [PDF]
Flavell R. B. +17 more
core +1 more source
Molecular cloning, purification, and biochemical characterization of recombinant isocitrate dehydrogenase from Streptomyces coelicolor M-145 [PDF]
Tóshiko Takahashi-Íñiguez +3 more
openalex +1 more source
Deregulated enhancer‐promoter communication in cancer through altered nuclear architecture
Abstract Enhancers are critical regulators of gene expression. Structural variations in cancer genomes can lead to enhancer hijacking, where oncogenes are activated by mistargeted enhancer activity. Novel enhancer‐promoter interactions may also arise through chromosomal rearrangements that create extrachromosomal DNA elements.
Isabelle Seufert +3 more
wiley +1 more source
The Krebs Cycle Enzyme Isocitrate Dehydrogenase 3A Couples Mitochondrial Metabolism to Synaptic Transmission [PDF]
Berrak Uğur +9 more
openalex +1 more source

