Results 81 to 90 of about 343,303 (317)
Autocrine IFN-I inhibits isocitrate dehydrogenase in the TCA cycle of LPS-stimulated macrophages.
Journal of Clinical Investigation, 2019 Macrophage activation in response to LPS is coupled to profound metabolic changes, typified by accumulation of the TCA cycle intermediates citrate, itaconate, and succinate.
D. D. De Souza +11 more
semanticscholar +1 more source
Animal, 2022 The enzyme isocitrate dehydrogenase (EC 1.1.1.42; 1; NADP+ dependent) located in the mammary cell cytosol mediates the synthesis of the majority of reducing equivalents for the energetically demanding milk fat and cholesterol synthesis in mammary cell ...
T. Larsen +3 more
doaj
Enzymatic AND-Gate Based on Electrode-Immobilized Glucose-6-Phosphate Dehydrogenase: Towards Digital Biosensors and Biochemical Logic Systems with Low Noise [PDF]
Biosens. Bioelectron. 25, 695-701 (2009), 2009 Electrode-immobilized glucose-6-phosphate dehydrogenase is used to catalyze an enzymatic reaction which carries out the AND logic gate. This logic function is considered here in the context of biocatalytic processes utilized for the biocomputing applications for "digital" (threshold) sensing/actuation.
arxiv +1 more source
Genetics in Medicine, 2018 Metabolic aberrations have been described in neoplasms with pathogenic variants (PV) in the Krebs cycle genes encoding succinate dehydrogenase (SDH), fumarate hydratase (FH) and isocitrate dehydrogenase (IDH).
S. Richter +22 more
semanticscholar +1 more source
Multimodal MRI features predict isocitrate dehydrogenase genotype in high-grade gliomas
Neuro-Oncology, 2017 Background. High-grade gliomas with mutations in the isocitrate dehydrogenase (IDH) gene family confer longer overall survival relative to their IDH-wild-type counterparts.
Biqi Zhang +9 more
semanticscholar +1 more source
Microbial Biotechnology, 2019 Summary Pichia pastoris KM71H (MutS) is an efficient producer of hard‐to‐express proteins such as the membrane protein P‐glycoprotein (Pgp), an ATP‐powered efflux pump which is expressed properly, but at very low concentration, using the conventional ...
Wan‐cang Liu +3 more
doaj +1 more source
Identification of Sequences Encoding Symbiodinium minutum Mitochondrial Proteins. [PDF]
, 2016 The dinoflagellates are an extremely diverse group of algae closely related to the Apicomplexa and the ciliates. Much work has previously been undertaken to determine the presence of various biochemical pathways within dinoflagellate mitochondria ...
Butterfield, Erin R. +2 more
core +4 more sources
Characterizing fruit ripening in plantain and Cavendish bananas: A proteomics approach [PDF]
, 2020 The fruit physiology of banana cultivars other than Cavendish is poorly understood. To study the ripening process, samples were taken daily from plantain and Cavendish bananas and the ripening stages were determined. We present data from the green to the
Bhuiyan, F. +3 more
core +1 more source
Incorporating expression data in metabolic modeling: a case study of lactate dehydrogenase [PDF]
J Theor Biol 240: 464-474 (2006), 2005 Integrating biological information from different sources to understand cellular processes is an important problem in systems biology. We use data from mRNA expression arrays and chemical kinetics to formulate a metabolic model relevant to K562 erythroleukemia cells. MAP kinase pathway activation alters the expression of metabolic enzymes in K562 cells.
arxiv +1 more source
Single muscle fiber proteomics reveals unexpected mitochondrial specialization [PDF]
, 2015 Mammalian skeletal muscles are composed of multinucleated cells termed slow or fast fibers according to their contractile and metabolic properties. Here, we developed a high-sensitivity workflow to characterize the proteome of single fibers.
A. S., Deshmukh +8 more
core +1 more source