Results 101 to 110 of about 190,806 (273)

Arabidopsis thaliana mRNA for isocitrate dehydrogenase gen bank AJ437268

open access: yes, 2002
LOCUS AJ437268 1610 bp mRNA linear PLN 15-APR-2005 DEFINITION Arabidopsis thaliana mRNA for isocitrate dehydrogenase. ACCESSION AJ437268 VERSION AJ437268.1 GI:19171468 KEYWORDS IDH gene; isocitrate dehydrogenase ...
De Bellis   +4 more
core  

Cyclic AMP-independent phosphorylation of Escherichia coli isocitrate dehydrogenase [PDF]

open access: yes, 1983
The phosphorylation of NADP-specific isocitrate dehydrogenase in a wild-type and in an adenylate cyclase deletion mutant of Escherichia coli has been investigated.
Reeves, Henry C.   +3 more
core   +1 more source

The FGF/FGFR System in the Biology and Therapeutic Landscape of Pediatric CNS Tumors

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Central nervous system (CNS) tumors are the most common solid malignancies in children, comprising a highly heterogeneous group of neoplasms defined by distinct molecular alterations and clinical behaviors. Advances in molecular genetics have underscored the relevance of specific signaling pathways in driving pediatric tumorigenesis, among ...
Serena Filiberti   +6 more
wiley   +1 more source

A real-world study of adverse drug reactions of two isocitrate dehydrogenase inhibitor based on the US FDA adverse event reporting system and VigiAccess databases

open access: yesFrontiers in Pharmacology
Background and objectivesIsocitrate dehydrogenase (IDH) inhibitor drugs (Enasidenib, Ivosidenib) restore normal metabolism and epigenetic regulation in cells, offering a precision-targeted therapeutic option for acute myeloid leukemia (AML) patients with
Mengmeng Peng   +11 more
doaj   +1 more source

Isocitrate dehydrogenase of the thermoacidophilic archaebacterium Sulpholobus acidocaldarius [PDF]

open access: yes, 1984
The thermoacidophilic archaebacterium, Sulpholobus acidocaldarius has been found to possess both NAD- and NADP-dependent isocitrate dehydrogenase activities. Evidence is presented to suggest that both enzymic activities are functions of the same protein:
Wood, Pauline A.   +3 more
core   +1 more source

Host‐induced silencing of the Minc09294 effector gene impairs Meloidogyne incognita and M. Enterolobii infection

open access: yesPest Management Science, EarlyView.
Host‐induced gene silencing of the effector candidate Minc09294 significantly impairs Meloidogyne incognita parasitism, markedly reducing gall formation, reproduction, and the development of specialized giant cells, with partial cross‐species effects on M.
João Pedro Abreu‐Sousa   +16 more
wiley   +1 more source

Extraneural and extracranial metastatic astrocytoma with primitive neuroectodermal component: a case report

open access: yesJournal of Medical Case Reports
Background Astrocytoma is a highly malignant tumor of the central nervous system with limited survival, despite standard multimodal therapies. While typically remains confined to the central nervous system, rare instances of extraneural and extracranial ...
Frayne Gomez   +3 more
doaj   +1 more source

Evidence for an arginine residue at the coenzyme-binding site of Escherichia coli isocitrate dehydrogenase [PDF]

open access: yes, 1989
The arginine-specific reagent phenylglyoxal inactivated the active, dephosphorylated, form of Escherichia coli isocitrate dehydrogenase rapidly in a pseudo-first-order process. Both NADP+ and NADPH protected the enzyme against inactivation. Phenylglyoxal
H G Nimmo   +3 more
core   +1 more source

High‐Altitude Adaptation of Frogs (Case Study: Nanorana parkeri): From Physiological Phenotypes to AltitudeOmics

open access: yesIntegrative Zoology, EarlyView.
High altitudes are challenging for the animals that inhabit these environments. The Xizang plateau frog (Nanorana parkeri) survives in high‐altitude environments through a synergistic strategy of metabolic remodeling and protein expression adjustment to optimize energy efficiency and enhance cellular protection.
Xuejing Zhang   +6 more
wiley   +1 more source

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