Results 141 to 150 of about 90,599 (289)

Society for Endocrinology Clinical Practice Guideline for the Evaluation of Androgen Excess in Women

open access: yesClinical Endocrinology, Volume 103, Issue 4, Page 540-566, October 2025.
ABSTRACT Context Androgen excess is common in women and refers to clinical or biochemical evidence of elevated androgenic steroids such as testosterone. It is associated with underlying polycystic ovary syndrome in the majority of cases. However severe androgen excess is less common and may indicate the presence of underlying adrenal or ovarian ...
Yasir S. Elhassan   +14 more
wiley   +1 more source

The Cardiac Sodium Channel Safety Profile of Cenobamate at Therapeutic Concentrations: In Vitro Analyses

open access: yesClinical and Translational Science, Volume 18, Issue 10, October 2025.
ABSTRACT The US Food and Drug Administration (FDA) issued a Drug Safety Communication for the antiseizure drug lamotrigine (Lamictal), warning of the risk of QRS prolongation and cardiac arrhythmias. The FDA also requested that other antiseizure medications with a similar mechanism of action (e.g., block of neuronal sodium channels), including ...
William J. Crumb Jr   +2 more
wiley   +1 more source

Purification and Characterization of Membrane-Bound Polyphenol Oxidases and Peroxidases from Metroxylon Sagu Rottb [PDF]

open access: yes, 2003
The histochemical studies indicated that Metroxylon sagu polyphenol oxidases (mPPO: E.C.1.10.3.2) and peroxidase (mPOD: E.C.1.11.1.7) were cellular membrane-bound enzyme. The enzymes were isolated using temperature-induced phase partitioning technique
Hassan Onsa, Galila
core  

TyG‐BMI index as a valuable risk of acute kidney injury in patients with heart failure: Insights from the MIMIC‐IV and eICU cohorts

open access: yesJournal of Diabetes Investigation, Volume 16, Issue 10, Page 1844-1858, October 2025.
While elevated triglyceride glucose‐body mass index (TyG‐BMI) predicts adverse outcomes in heart failure (HF), its association with acute kidney injury (AKI) risk was unclear. This study examined this link. Using data from MIMIC‐IV v3.1 (1,250 patients) and eICU‐CRD v2.0 (2,300 patients), researchers analyzed associations between TyG‐BMI and AKI ...
Yiming Hua   +9 more
wiley   +1 more source

Análisis de la variabilidad genética de la colección colombiana de musáceas usando marcadores isoenzimáticos Analysis of the genetic variability of colombian collection of Musaceae using isozyme markers

open access: yesActa Agronómica, 2011
La Colección Colombiana de Musáceas (CCM) es la única a nivel mundial que representa un alto valor por ser la que posee introducciones andinas de altura (> 1500 m.s.n.m.).
Martha C Giraldo   +3 more
doaj  

Identification of a hydroxycinnamoyl‐CoA double bond reductase (HDR) affirms multiple pathways for dihydrochalcone formation in apple

open access: yesPlant Biotechnology Journal, Volume 23, Issue 10, Page 4522-4535, October 2025.
Summary Dihydrochalcones are secondary metabolites with manifold dietary and pharmaceutical properties, but with a yet unclear function in plants. The abundance of dihydrochalcones, particularly phloridzin, makes Malus ssp. unique in the plant kingdom. The gene(s)/enzyme(s) for the key reaction in phloridzin biosynthesis, the reduction in the C3‐bridge
Susan Schröpfer   +14 more
wiley   +1 more source

Home - About - Disclaimer - Privacy