Results 141 to 150 of about 92,196 (294)
The role of statin drugs in combating cardiovascular diseases –A review [PDF]
Statins clearly confer substantial benefit in people with established cardiovascular (CV) disease. Increased cholesterol levels have been associated with cardiovascular diseases (CVD), and statins are therefore used in the prevention of these diseases ...
Suresh Pichandi , Palanisamy Pasupathi, Y.Yagneswara Rao, Jawahar Farook, Athimoolam Ambika, Babu Shankar Ponnusha , Sathiyamoorthy Subramaniyam, Rajaram Virumandy, Boopathi subramaniyam Int J Cur Sci Res.
core
Lactylation, linked to glycolysis, is poorly understood in regulation. It is found that LDHA is lactylated at Lys81/Lys318 by AARS1, boosting its activity and cellular lactylation via positive feedback in LUAD. Lactylation regulates NHEJ‐related proteins; their delactylation impairs NHEJ and increases cisplatin sensitivity, offering anticancer insights.
Jizhuo Li +11 more
wiley +1 more source
: To evaluate the effect of accelerated aging to overcome dormancy of hybrid Brachiaria cv. Mulato II (U. brizantha x U. decumbens x U. ruziziensis), seeds were collected from two lots with and without scarification, submitted to 42 °C and high humidity (
Diego de Sousa Pereira +4 more
doaj +1 more source
Secretory carbonic anhydrase isoenzyme (CA VI) in human serum [PDF]
Jyrki Kivelä +5 more
openalex +1 more source
Characterization of cyclic nucleotide phosphodiesterase isoenzymes in the human ureter and their functional role in vitro [PDF]
Forssmann, W. G. +6 more
core +1 more source
Ythdc1‐p300‐Klf5 Complex‐Mediated Golgi Dysfunction Promotes Aortic Aneurysm
In their Research Article (DOI: https://doi.org/10.1002/advs.202512116* lF: 14.1 Q1), Wenli Wang and co‐workers identifies a novel lncRNA m6A modification‐dependent regulatory mechanism of vascular homeostasis, and constructs a predictive model for post‐operative short‐term death based on AD patient's features, providing a platform to be able to ...
Wen‐Li Wang +22 more
wiley +1 more source
Dissection of the Functional Differences between Human Secretory Pathway Ca2+/Mn2+-ATPase (SPCA) 1 and 2 Isoenzymes by Steady-state and Transient Kinetic Analyses [PDF]
Leonard Dode +6 more
openalex +1 more source
Frailty and Oncology: An Increasingly Common Combination
Frailty is an essential clinical parameter that should guide the individualization of therapeutic strategies in oncology to promote more effective, patient‐centered medicine. This narrative review explores the importance of incorporating frailty assessment and optimizing patients' clinical status to improve cancer treatment outcomes.
Yanira Hernández‐Aguiar +2 more
wiley +1 more source
Incubation of human plasma with the tear gas 2‐chloroacetophenone (CN) led to the formation of acetophenone (AcPhen)‐adducts with the small plasma thiols glutathione, homocysteine, and cysteine persulfide. The AcPhen‐adducts were either bound to an organic thiol‐group or to an organic persulfide. The adducts were detected with a mass spectrometry‐based
Paula Helena Sieber +3 more
wiley +1 more source

