Results 41 to 50 of about 89,619 (307)
A Egeria najas é uma espécie aquática submersa nativa da bacia hidrográfica do rio Paraná. Com o represamento das águas do rio para geração de energia elétrica a espécie tem mudado seu comportamento de colonização dos leitos dos rios e ocorrido em ...
Edson S. Mori+5 more
doaj +1 more source
Isoenzyme electrophoresis of 30 isolates of Giardia from humans and felines [PDF]
Thirty isolates of Giardia duodenalis from humans and felines were compared by isoenzyme electrophoresis. Using 10 enzyme systems, 13 different zymodemes were distinguished. The majority of zymodemes could be divided into two groups: one group comprising
Lymbery, A.J.+2 more
core +2 more sources
Improved C5-Amide Bioisosteres for Human Neuraminidase 1 Inhibitors Based on 2-Deoxy-2,3-Didehydro-N-Acetyl Neuraminic Acid. [PDF]
This article describes the development of improved NEU1 inhibitors based on the 2‐deoxy‐2,3‐didehydro‐N‐acetyl neuraminic acid scaffold. A series of candidate inhibitors are designed containing bioisosteres of the C5‐amide group and evaluated for activity against NEU1‐4 enzymes.
Radwan M, Carvajal EG, Cairo CW.
europepmc +2 more sources
Utilizando dados obtidos sobre a atividade de isoenzinias de esterase e peroxidase, o teor de proteína total solúvel e o nível de sólidos solúveis (sacarose, grau Brix, bem como parâmetros organográficos de colmo e folhas já publicados), foi possível ...
M.De Almeida+2 more
doaj +1 more source
Influence of pH and type of myrosinase complex on the products obtained in the myrosinase catalysed hydrolysis of glucosinolates – a MECC study [PDF]
Environmental conditions, e.g. pH and the presence of Fe2+ are well known factors that influence the product profile of the myrosinase catalysed hydrolysis of glucosinolates.
Bellostas, Natalia+2 more
core
Peroxidase gene discovery from the horseradish transcriptome [PDF]
BACKGROUND: Horseradish peroxidases (HRPs) from Armoracia rusticana have long been utilized as reporters in various diagnostic assays and histochemical stainings.
Glieder, Anton+4 more
core +2 more sources
EBBP expression is significantly upregulated in DOX‐treated cardiomyocytes. Mechanistically, EBBP interacts with GRP78 to mediate K63‐linked ubiquitination, thereby attenuating the inhibitory GRP78‐PERK interaction and triggering activation of the PERK‐mediated integrated stress response (ISR).
Zilong Chen+9 more
wiley +1 more source
Taxonomic position of Pinus uliginosa Neumann as related to other taxa of Pinus mugo complex
Studies on taxonomic position of Pinus uliginosa Neumann, P. uncinata Ram. and P. mugo Turra, indicate a significant specificity of P. uliginosa population from Wielkie Torfowisko Batorowskie Peat Bog.
Wiesław Prus-Głowacki+2 more
doaj +1 more source
Herpes Simplex Virus Type 1 (HSV‐1) infection triggers metabolic reprogramming in corneal cells, shifting from mitochondrial respiration to aerobic glycolysis with marked upregulation of Hexokinase‐2 (HK2). This study identifies HK2 as a therapeutic target: inhibiting HK2 with lonidamine significantly reduces viral replication and promotes corneal ...
Dan Jiang+9 more
wiley +1 more source
Inducing ferroptosis is a promising strategy for combating tumor resistance. Upregulated PIP5K1A competes with NRF2 for KEAP1 binding, which decreases the ubiquitination degradation of NRF2 and promotes its nuclear translocation, thereby suppressing ferroptosis, and ultimately driving hepatocellular carcinoma (HCC) tumorigeneses and sorafenib ...
Mengzhou Guo+9 more
wiley +1 more source