Results 111 to 120 of about 35,087 (244)

Mitochondrial reprogramming in lung cancer: a therapeutic vulnerability and a strategy for reversing drug resistance

The Journal of Pathology, Volume 269, Issue 2, Page 149-163, June 2026.
Abstract The conceptualization of mitochondria, previously restricted to their function as cellular ‘powerhouses’, has evolved to recognize their function as central coordinating hubs for the orchestration of cancer cell metabolism, signaling, and fate determination.
Woo Hyun Park
wiley   +1 more source

Lupin (Lupinus angustifolius) as a Protein‐Rich Emerging Crop Adapted to Uruguay: Nutritional and Functional Potential

Sustainable Food Proteins, Volume 4, Issue 2, June 2026.
Characterization of Lupinus angustifolius cultivated in Uruguay. The figure summarizes the experimental workflow applied to six Lupinus angustifolius samples cultivated in Uruguay. After sample preparation, different analytical approaches were performed: Proximate composition determination of moisture, ash, crude protein, and crude fat by standard AOAC
Matías Rodríguez‐Elhordoy, Jessica Báez, Victoria Olt, Adriana Maite Fernández‐Fernández, Natalia Martínez, Bruno Irigaray, Javier Silva, Mariela Pistón, Daniel Vázquez, Alejandra Medrano   +9 more
wiley   +1 more source

Biochanin A, a Plant Isoflavone, Disrupts Peptidoglycan Biosynthesis by Downregulating femA and femB, and Impairs Cell Wall Integrity in Multidrug-Resistant Staphylococcus aureus

Antibiotics
Background/Objectives: The global rise in multidrug-resistant Staphylococcus aureus (MDR-SA) threatens the efficacy of existing antibiotics and necessitates alternative antibacterial strategies.
Jade Joshua R. Teodosio, Kathryn Ann H. Dizon, Julyanna R. Bruna, Jan Vincent N. Sollesta, Zenith M. Villorente, Jonel P. Saludes, Doralyn S. Dalisay   +6 more
doaj   +1 more source

Machine Learning Unveils Dietary Antioxidants as Influential Factors for Diabetes‐Cancer Comorbidity: Insights From National Health and Nutrition Examination Survey

Food Science &Nutrition, Volume 14, Issue 5, May 2026.
This study employs an interpretable machine learning framework to predict diabetes‐cancer comorbidity, with the Random Forest and LightGBM models demonstrating exceptional performance. SHAP value analysis reveals that while advanced age and cardiometabolic dysfunctions serve as primary risk drivers, dietary antioxidants (particularly daidzein and ...
Ming Xu, Ru Li, Shuqing Jin, Qinhao Liu, Hongxia Wei, Zhe Li, Yuchen Sun, Yi Zhang, Yunfeng Liu   +8 more
wiley   +1 more source

Effect of Two Production Methods on Macro Nutrient and Isoflavone-aglycone Composition in Tempeh Produced by Household Industries [PDF]

, 2013
Background: Tempeh was used as nutrition source and healthy food. Tempeh household industries apply different production methods. Those different could lead to different microbial composition and hence different chemical composition of tempeh.
Efriwati, E. (Efriwati), Nuraida, L. (Lilis)   +1 more
core  

Enhanced Bioactivity of Puerariae Radix‐ Hovenia Seed Extracts Through Lactiplantibacillus plantarum and Lacticaseibacillus paracasei Co‐Fermentation: Impact on Alcoholic Liver Injury and Macrophage Polarization

Food Science &Nutrition, Volume 14, Issue 5, May 2026.
Puerariae Radix and Hovenia Seed were co‐fermented with Lactiplantibacillus plantarum and Lacticaseibacillus paracasei to produce PHF. In a mouse model of alcohol‐induced liver injury, PHF intervention alleviated liver damage. The underlying mechanism may be related to the regulation of macrophage polarization.
Yunpeng Sun, Shen Yao, Yuan Cui, Yiyu Ni, Meichen Liu, Daqing Zhao, Shiting Yu, Siming Wang   +7 more
wiley   +1 more source

Dietary Polyphenols in Non‐Communicable Chronic Diseases: Neuro–Enteric Mechanisms, Multi‐Omics Biomarkers and Translational Opportunities

Food Science &Nutrition, Volume 14, Issue 5, May 2026.
This illustration highlights how dietary polyphenols from foods like berries, grapes, and green tea travel through the gut, where microbiota transform them into bioactive metabolites. These metabolites pass into the bloodstream, strengthen the gut barrier, and ultimately reach the brain, supporting neuroprotection through antioxidative and anti ...
Adnan Akif, Jannatul Wahid Munami, Rajib Das, Nusrat Jahan Shawon   +3 more
wiley   +1 more source

Purification of Biotransformation Products of Cis-Isoflavan-4-ol by Biphenyl Dioxygenase of Pseudomonas pseudoalcaligenes KF707 Strain Expressed in Escherichia coli

Makara Seri Sains, 2013
Isoflavone has multiple beneficial effects on human health, especially through its antioxidant and anticancer activities. The biotransformation of isoflavone using byphenyl dioxygenase could be performed to extend the diversity of flavonoids and to ...
Tri Ratna Sulistiyani
doaj  

UV-B Radiation Exhibited Tissue-Specific Regulation of Isoflavone Biosynthesis in Soybean Cell Suspension Cultures

Foods
Isoflavones, a class of substances with high biological activity, are abundant in soybeans. This study investigated isoflavone biosynthesis in soybean cell suspension cultures under UV-B radiation.
Mian Wang, Yiting Wang, Muhammad Bilal, Chong Xie, Pei Wang, Xin Rui, Runqiang Yang   +6 more
doaj   +1 more source

Hubungan antara Asupan Isoflavon Kedelai dengan Kejadian Sindrom Perimenopause di Kecamatan Jebres, Surakarta [PDF]

, 2016
Background: Perimenopausal syndrome in most women caused by estrogen deficiency due to aging-related changes in ovarian. Isoflavone is a natural phytochemical compound contained in several types of plants and has partial agonist or antagonist effects on ...
NARESWARI, DEWI
core