Results 121 to 130 of about 23,559 (275)

Genome-Wide Characterization of the Soybean GmCXE Gene Subfamily Reveals GmCXE54 as a Candidate Gene for Root Isoflavone Accumulation

Agronomy
Carboxylesterases (CXEs) participate in diverse plant metabolic processes, including isoflavone biosynthesis. However, the soybean GmCXE subfamily remains poorly characterized, especially in relation to root isoflavone accumulation and the response to ...
Xu Wu, Zhongqiu Fu, Wantong Zhao, Xiangkun Meng, Shibo Du, Yanzeng Feng, Xiaozhu Chang, Xue Zhao, Yingpeng Han, Yuhe Wang   +9 more
doaj   +1 more source

Assessment of the Targeted Therapeutic Potential of Naringenin‐Benzyl Piperazine Derivatives on Hypoxia‐Induced JAK/STAT Pathway in Breast and Ovarian Cancers

Archiv der Pharmazie, Volume 359, Issue 9, September 2026.
The synthesized naringenin‐benzyl piperazine derivatives 3b, 3f, and 3g exhibited potent antiproliferative and cytotoxic activities on breast tumors (MCF7 (ER‐α+), SK‐Br, MDA‐MB‐231) and ovarian cancer cells (NIH‐OVCAR‐3, and SKOV‐3). 3f was found to have the highest apoptotic effect among the other derivatives.
Hafize Özcan, Oğuzhan Doğanlar, Zeynep Banu Doğanlar, Ayşen Şuekinci Yılmaz, Ömer Zaim   +4 more
wiley   +1 more source

Large inter-individual variation in isoflavone plasma concentration limits use of isoflavone intake data for risk assessment

, 2014
Isoflavones are present in soy foods and soy-based supplements. Despite low plasma isoflavone concentrations in the general Western population, concentrations in supplement users exceed those suggested to be beneficial for health in Asian populations ...
Mensink, M, P C Hollman, van der Velpen, V, van der Velpen, V., P van't Veer, E G Schouten, Hollman, P C, Geelen, A, V van der Velpen, Hollman, P.C.H., van Nielen, M., van 't Veer, P., van Nielen, M, M Mensink, Mensink, M.R., Schouten, E.G., Van't Veer, P, A Geelen, Schouten, E G, M van Nielen, Geelen, A.   +20 more
core   +1 more source

Natural Compounds Targeting Oncogenic Signaling Networks in Glioblastoma: Molecular Mechanisms, Translational Advances, and Clinical Perspectives

Brain and Behavior, Volume 16, Issue 9, September 2026.
Glioblastoma (GBM) is a highly aggressive brain tumor with a poor prognosis, driven by abnormal signaling pathways that promote growth and resistance to treatment. Conventional therapies are inadequate, highlighting the need for novel multitargeted approaches.
Mehrukh Zehravi, Md Abul Hassan, Md. Al Amin, Sherouk Hussein Sweilam, Jeetendra Kumar Gupta, Ramenani Hari Babu, Pericharla Venkata Narasimha Raju, Krishna Vamsi Kandimalla, Phanindra Erukulla, Patibandla Jahnavi, Rajeshwar Vodeti, Abdul Ajeed Mohathasim Billah, Safia Obaidur Rab, Sharuk L. Khan   +13 more
wiley   +1 more source

Phytochemical Profiling and Evaluation of Antibacterial, Anticancer, Anti‐inflammatory, and Wound‐Healing Activities of Endophytic Fungi Isolated From Atalantia racemosa

Chemistry &Biodiversity, Volume 23, Issue 9, September 2026.
ABSTRACT Endophytic fungi are recognized as prolific sources of structurally diverse secondary metabolites with significant pharmaceutical potential. In the present study, endophytic fungi were isolated from healthy tissues of Atalantia racemosa (Rutaceae), an ethnomedicinal plant traditionally used for respiratory disorders and blood purification.
Sushma M, Arun Shettar, Joy Hoskeri, Vedamurthy A B   +3 more
wiley   +1 more source

Exploring microbial dynamics and metabolomic profiling of isoflavone transformation in black and yellow soybean tempe for sustainable functional foods

Food Chemistry: Molecular Sciences
Tempe, a traditional Indonesian fermented food, is rich in bioactive isoflavones and peptides, offering significant health benefits. This study explores how fermentation methods and soybean varieties shape isoflavone profiles and microbial communities ...
Siti Nurmilah, Andri Frediansyah, Yana Cahyana, Roostita L. Balia, Bibin Bintang Andriana, Gemilang Lara Utama   +5 more
doaj   +1 more source

A new Isoflavone from Genista corsica

, 2000
A new isoflavone (1), dihydroisoderrondiol [(3''S,4''R)-5,7,3'',4''- tetrahydroxy-2'',2''-dimethyl- 3'',4''dihydropyrano(5'',6'';3'',4'')isoflavone], was isolated from aerial parts of Genista corsica, together with 11 previously known compounds [daidzein,
GIACHI I., MORELLI I., POTENZA D., PISTELLI, LUISA   +3 more
core   +1 more source

First Report on the Phytochemical and Pharmacological Properties of Hedysarum yilmazunalii

Chemistry &Biodiversity, Volume 23, Issue 9, September 2026.
Hedysarum yilmazunalii was collected from Erzincan, Türkiye. The leaf, stem, and root parts were then used for methanolic extraction. The extracts were analyzed for their phytochemical composition by LC–MS/MS and tested for antioxidant, enzyme inhibitory, and antiproliferative activities.
Etem Osma, Tuğçe Varol, Samed Şimşek, Sevgi Altın, Mustafa Abdullah Yılmaz, Ali Aydın, Müjgan Elveren, Ali Kandemir   +7 more
wiley   +1 more source

Evaluation of Isoflavone Content in South Dakota Soybean Cultivars

, 1996
Soy foods represent the only substantial dietary source of isoflavones, phytochemicals demonstrated to prevent a number of conditions associated with cancer and heart disease, both in vitro and in vivo. To date, twelve isoflavones have been identified in
Self, Maurica Sherrard
core   +1 more source

Differentially Expressed Genes Related to Isoflavone Biosynthesis in a Soybean Mutant Revealed by a Comparative Transcriptomic Analysis

Plants
Soybean [Glycine max (L.) Merr.] isoflavones, which are secondary metabolites with various functions, are included in food, cosmetics, and medicine.
Jung Min Kim, Jeong Woo Lee, Ji Su Seo, Bo-Keun Ha, Soon-Jae Kwon   +4 more
doaj   +1 more source