Results 41 to 50 of about 45,051 (231)

Soy Isoflavones Induce Cell Death by Copper-Mediated Mechanism: Understanding Its Anticancer Properties

Molecules, 2023
Cancer incidence varies around the globe, implying a relationship between food and cancer risk. Plant polyphenols are a class of secondary metabolites that have recently attracted attention as possible anticancer agents.
Mohd Farhan, Mohamed El Oirdi, Mohammad Aatif, Insha Nahvi, Ghazala Muteeb, Mir Waqas Alam   +5 more
doaj   +1 more source

Preliminary investigation of the effects of long-term dietary intake of genistein and daidzein on hepatic histopathology and biochemistry in domestic cats (Felis catus) [PDF]

, 2012
Dietary isoflavones have been hypothesised to play a role in hepatic veno-occlusive disease in captive exotic felids, although empirical evidence is lacking. This study aimed to investigate the effect of long-term (>1 year) dietary genistein and daidzein
Cave, NJ, Roe, WD, Thomas, DG, Ugarte, CE, Whitehouse-Tedd, KM   +4 more
core   +1 more source

Genistein in Prostate Cancer Prevention and Treatment

Proceedings, 2020
Botanical compounds have been found to modulate genetic and epigenetic pathways of cancer development and progression. We have studied nutritional interventions, with emphasis on soy isoflavones.
Omer Kucuk
doaj   +1 more source

Flavonoids and Other Polyphenols Act as Epigenetic Modifiers in Breast Cancer. [PDF]

, 2020
Breast cancer is a common cancer that occurs due to different epigenetic alterations and genetic mutations. Various epidemiological studies have demonstrated an inverse correlation between breast cancer incidence and flavonoid intake.
Anwar, Hina, Badgeley, Aja, Lakshmikuttyamma, Ashakumary, Lawrence, Katharine, Murphy, Paige, Selvakumar, Priyanga, Sharma, Urvashi   +6 more
core   +1 more source

Phytoestrogens [PDF]

, 2004
Collectively, plants contain several different families of natural products among which are compounds with weak estrogenic or antiestrogenic activity toward mammals.
Adlercreutz H, Alekel DL, Bhathena SJ, Bielenberg J, Biendl M, Boller B, Dai Q, Day JK, de Kleijn MJJ, den Tonkelaar I, denTonkelaar I, Dewick PM, Ebisawa H, Fritz WA, Guo TL, Hodgson JM, Horn-Ross PL, ILDIS, Kim CS, Lamartiniere CA, Maggiolini M, Maskarinec G, McCann SE, Mentor MR, MerzDemlow BE, Newbold RR, Pan W, Peluso MR, Richard A. Dixon, Seested S, Setchell KDR, Setchell KDR, Setchell KDR, Slavin JL, Stevens JF, Whitten PL, Yanagihara K, Zhang Y   +37 more
core   +1 more source

Potential Effects of Dietary Isoflavones on Drug-Induced Liver Injury

Journal of Food Quality, 2021
Numerous prescribed drugs and herbal and dietary supplements have been reported to cause drug-induced acute liver injury, which is a frequent cause of acute liver failure (ALF).
Liangliang Yao, Muhammad Farrukh Nisar, Tingdong Yan, Chunpeng (Craig) Wan   +3 more
doaj   +1 more source

Neuroprotective Effects of Time‐Restricted Feeding Combined With Different Protein Sources in MPTP‐Induced Parkinson's Disease Mice Model and Its Modulatory Impact on Gut Microbiota Metabolism

Advanced Science, EarlyView.
Time‐restricted feeding (TRF) exerts protein‐dependent neuroprotective effects in an MPTP‐induced Parkinson's disease model. In casein‐fed mice, TRF improves gut barrier integrity and reduces neuroinflammation, possibly via modulation of Allobaculum and BCAAs.
Ting Li, Jian Wu, Sheng‐Yang Zhou, Ming‐An Li, Li‐Ping Zhao, Ao Wang, Yi‐Zhi Song, Wen‐Yan Huang, Lu‐Lu Tan, Chen‐Meng Qiao, Wei‐Jiang Zhao, Chun Cui, Yan‐Qin Shen   +12 more
wiley   +1 more source

Isoflavones, genistein and daidzein, regulate mucosal immune response by suppressing dendritic cell function. [PDF]

PLoS ONE, 2012
Lipopolysaccharide (LPS), a component of gram-negative bacterial cell walls, has been shown to have a strong adjuvant effect towards inhaled antigens contributing to airway inflammation.
John Wei, Shiven Bhatt, Lisa M Chang, Hugh A Sampson, Madhan Masilamani   +4 more
doaj   +1 more source

Bioengineered Isoflavone–Probiotic Functional Foods for Sustainable Modulation of Metabolic and Reproductive Health in PCOS

Food Bioengineering, EarlyView.
Synergistic isoflavone‐probiotic action modulated metabolic, microbial and ovarian pathway ABSTRACT Polycystic ovary syndrome (PCOS) is a prevalent metabolic–endocrine disorder characterized by insulin resistance, hyperandrogenism, chronic inflammation, oxidative stress, and ovarian dysfunction, with growing evidence implicating gut microbiota ...
Jeyavelkumaran Renukadevi, Panneerselvam Sneha, Dhanapal Saravanan Mridula, Keerthivasan Nimithasree, Valliappan Sanjay   +4 more
wiley   +1 more source

Advances in synthesizing plant-derived isoflavones and their precursors with multiple pharmacological activities using engineered yeasts

Microbial Cell Factories
Isoflavones such as daidzein and genistein are naturally occurring compounds found in plants such as legumes. They have diverse pharmacological activities, making them valuable in the food, pharmaceutical, and cosmetic industries.
Wenhui Niu, Jingxian Zhang, Lingbo Qu, Xiao-Jun Ji, Yongjun Wei   +4 more
doaj   +1 more source