Results 101 to 110 of about 301,160 (383)

Evolving Platinum‐Copper Nanostructures for Enhanced Photothermal Therapy and Controlled Copper Release in Cancer Therapy

open access: yesAdvanced Functional Materials, EarlyView.
Platinum‐Copper bimetallic nanoparticles may evolve depending on their synthesis under tumor microenvironment conditions and play a dual role as chemotherapeutic agents after releasing Cu ions and as near infrared photothermal agents with the Pt‐rich remaining frames.
Jose I. Garcia‐Peiro   +7 more
wiley   +1 more source

Isoflurane depresses hippocampal CA1 glutamate nerve terminals without inhibiting fiber volleys

open access: yesBMC Neuroscience, 2006
Background Anesthetic-induced CNS depression is thought to involve reduction of glutamate release from nerve terminals. Recent studies suggest that isoflurane reduces glutamate release by block of Na channels.
MacIver M Bruce, Winegar Bruce D
doaj   +1 more source

Impact of isoflurane on malignant capability of ovarian cancer in vitro.

open access: yesBritish Journal of Anaesthesia, 2015
BACKGROUND Metastatic recurrence of ovarian cancer is the foremost cause of postoperative mortality. With recent research indicating that inhalation of anaesthetics may influence cancer cell behaviour, this study investigated the effects of isoflurane on
X. Luo   +7 more
semanticscholar   +1 more source

High‐Throughput Microfluidic‐Mediated Assembly of Layer‐By‐Layer Nanoparticles

open access: yesAdvanced Functional Materials, EarlyView.
The layer‐by‐layer (LbL) assembly of polymer films on nanoparticle (NP) surfaces is a promising technique for targeted drug delivery. Despite its success in preclinical mouse models, a current good manufacturing practices (cGMP) compliant, clinical‐scale production method has been lacking.
Ivan S. Pires   +4 more
wiley   +1 more source

Intraoperative administration of isoflurane improves survival in rats exposed to caecal ligation and puncture

open access: yesBJA Open, 2022
Background: Emerging data suggest that volatile anaesthetic agents may be protective during critical illness. Methods: Three-month-old Sprague Dawley rats were randomly allocated to one of four groups: isoflurane during surgery followed by 3 days of ...
Keita Ikeda   +2 more
doaj  

The Pharmacokinetics of Medetomidine Administered Subcutaneously during Isoflurane Anaesthesia in Sprague-Dawley Rats

open access: yesAnimals, 2020
Anaesthetic protocols involving the combined use of a sedative agent, medetomidine, and an anaesthetic agent, isoflurane, are increasingly being used in functional magnetic resonance imaging (fMRI) studies of the rodent brain.
Leila T. Kint   +7 more
doaj   +1 more source

Perioperative Neurocognitive Disorder: State of the Preclinical Science. [PDF]

open access: yes, 2020
The purpose of this article is to provide a succinct summary of the different experimental approaches that have been used in preclinical postoperative cognitive dysfunction research, and an overview of the knowledge that has accrued. This is not intended
Culley, Deborah J   +10 more
core  

A Vertically‐Stacked Optoelectronic Sensor for Localized Hemodynamics Monitoring

open access: yesAdvanced Functional Materials, EarlyView.
This work introduces a hemodynamics monitoring sensor that features vertically stacked microLEDs and a heterogeneously integrated photodetector. The vertically stacked microLEDs enable localized measurements, and by designing the interoptode distance according to the depth of the target region, this vertically stacked optoelectronic sensor is ...
Taeyeon Lee   +9 more
wiley   +1 more source

General anesthesia reduces complexity and temporal asymmetry of the informational structures derived from neural recordings in Drosophila

open access: yes, 2020
We apply techniques from the field of computational mechanics to evaluate the statistical complexity of neural recording data from fruit flies. First, we connect statistical complexity to the flies' level of conscious arousal, which is manipulated by ...
Cohen, Dror   +7 more
core   +1 more source

Inhalational or total intravenous anaesthesia: is total intravenous anaesthesia useful and are there economic benefits? [PDF]

open access: yes, 2011
PURPOSE OF REVIEW: The comparison of inhalational and intravenous anaesthesia has been the subject of many controlled trials and meta-analyses. These reported diverse endpoints typically including measures of the speed and quality of induction of ...
Holmes, KA, Sneyd, JR
core   +1 more source

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