Results 101 to 110 of about 307,909 (397)

A Vertically‐Stacked Optoelectronic Sensor for Localized Hemodynamics Monitoring

Advanced Functional Materials, EarlyView.
This work introduces a hemodynamics monitoring sensor that features vertically stacked microLEDs and a heterogeneously integrated photodetector. The vertically stacked microLEDs enable localized measurements, and by designing the interoptode distance according to the depth of the target region, this vertically stacked optoelectronic sensor is ...
Taeyeon Lee, Jieun Jung, Hyeongoh Park, Dongwuk Jung, Doyune Kim, Changeui Hong, Seungbeom Kang, Hyunsoo Kim, Tae Kim, Jongho Lee   +9 more
wiley   +1 more source

Isoflurane exposure during mid-adulthood attenuates age-related spatial memory impairment in APP/PS1 transgenic mice. [PDF]

PLoS ONE, 2012
Many in vitro findings suggest that isoflurane exposure might accelerate the process of Alzheimer Disease (AD); however, no behavioral evidence exists to support this theory.
Diansan Su, Yanxing Zhao, Huan Xu, Beilei Wang, Xuemei Chen, Jie Chen, Xiangrui Wang   +6 more
doaj   +1 more source

Isoflurane Is More Deleterious to Developing Brain Than Desflurane: The Role of the Akt/GSK3β Signaling Pathway

BioMed Research International, 2016
Demand is increasing for safer inhalational anesthetics for use in pediatric anesthesia. In this regard, researchers have debated whether isoflurane is more toxic to the developing brain than desflurane.
Guorong Tao, Q. Xue, Yan Luo, Guohui Li, Yimeng Xia, Buwei Yu   +5 more
semanticscholar   +1 more source

Cholesterol in mRNA‐Lipid Nanoparticles can be Replaced with the Synthetic Mycobacterial Monomycoloyl Glycerol Analogue MMG‐1

Advanced Functional Materials, EarlyView.
This study demonstrates that cholesterol in messenger RNA‐lipid nanoparticles (mRNA‐LNPs) can be completely replaced with an immunopotentiating lipid, i.e., a synthetic analogue of the C‐type lectin receptor agonist monomycoloyl glycerol (MMG‐1), without compromising physicochemical properties, in vivo transfection efficiency, and immunogenicity of the
Abhijeet G. Lokras, Saahil S. Baghel, Rune F. Jensen, Aneesh Thakur, Henrik Franzyk, Oskar Thofte, Marco Herrera‐Barrera, Madeleine Landry, Melike Ongun, Ahmad Tami, Marlene P. Thanthrige, Eva Callens, Corinne Beinat, Thomas Rades, Søren R. Paludan, Kristian Riesbeck, Ida Rosenkrands, Dennis Christensen, Gabriel K. Pedersen, Camilla Foged   +19 more
wiley   +1 more source

A comparison of sequential total and activated white cell count in patients undergoing coronary artery bypass grafting, using cardiopulmonary bypass, with and without a white cell filter

, 1999
Introduction Cardiopulmonary bypass (CPB) has been shown to induce a systemic inflammatory response similar to the local reaction seen after tissue damage [1].
D Johnson, DC Smith, JK Kirklin, JK Nanson, M Kulkarni, PJ Thurlow, SV Sheppard   +6 more
core   +1 more source

Functional Hydrogel for Modulating Lipid Droplets and Neuroinflammation in Head Injury

Advanced Functional Materials, EarlyView.
After TBI, elevated cholesterol levels in activated microglia lead to the accumulation of cholesterol esters in lipid droplets, exacerbating neuroinflammation. A β‐cyclodextrin‐conjugated GelMA (βCD‐GelMA) hydrogel is developed to promotes cholesterol efflux and reduces LDL influx, thereby alleviating intracellular cholesterol and lipid droplet buildup.
Feixiang Chen, Yvonne Shen, Yutong Shao, Tenghuan Ge, Haowen Qiao, Shangzhou Xia, Yafei Qu, Yuanpu Chiu, Ying Qin, Zhen Zhao   +9 more
wiley   +1 more source

Isoflurane conditioning improves functional outcomes after peripheral nerve injury in a sciatic cut repair murine model

Frontiers in Neurology
IntroductionAnesthetic conditioning has been shown to provide neuroprotection in several neurological disorders. Whether anesthetic conditioning provides protection against peripheral nerve injuries remains unknown.
Yameng Xu, Ying Yan, Gregory J. Zipfel, Gregory J. Zipfel, Matthew MacEwan, Wilson Z. Ray, Wilson Z. Ray, Wilson Z. Ray, Umeshkumar Athiraman, Umeshkumar Athiraman   +9 more
doaj   +1 more source

Effect of Isoflurane on the Hearing in Mice [PDF]

Korean Journal of Audiology, 2012
The aim of this study was to investigate the relationship between inhalation anesthetics and hearing in mice.As inhalation anesthetics, isoflurane was used. Auditory brainstem response and distortion product otoacoustic emission were used as measurement of hearing. Mice were divided into 2 groups.
Yun Suk Ahn, Joung Uk Kim, Jong Woo Chung, Jin Kyung Suh   +3 more
openaire   +3 more sources

Isoflurane promotes glucose metabolism through up-regulation of miR-21 and suppresses mitochondrial oxidative phosphorylation in ovarian cancer cells

Bioscience Reports, 2017
Ovarian cancer is one of the most lethal gynecologic malignancies in women. Isoflurane is one of the volatile anesthetics used extensively for inhalational anesthesia and gynecological surgery.
N. Guo, Jia-xin Zhang, Jing-Ping Wu, Ying-Hua Xu   +3 more
semanticscholar   +1 more source

Cell‐Delivering Injectable Hydrogels with Tunable Microporous Structures Improve Therapeutic Efficacy for Volumetric Muscle Loss

Advanced Functional Materials, EarlyView.
The study presents an injectable hydrogel with tunable microporosity to improve mesenchymal stem cell delivery for volumetric muscle loss treatment. Mesenchymal stem cells encapsulated in porous hydrogels significantly promote the spreading, proliferation, and cytokine secretion of mesenchymal stem cells.
Hana Yasue, Tetsushi Taguchi, Taka‐Aki Asoh, Akihiro Nishiguchi   +3 more
wiley   +1 more source