Results 81 to 90 of about 801 (163)

Isoginkgetin enhances adiponectin secretion from differentiated adiposarcoma cells via a novel pathway involving AMP-activated protein kinase [PDF]

Journal of Endocrinology, 2007
Adiponectin is an anti-diabetic hormone secreted byadipocytes. Circulating adiponectin levels are lower in obese and type II diabetic patients than in healthy people. Weight loss or thiazolidinedione treatment increases plasma adiponectin levels. Animal models and human studies suggest that elevated adiponectin levels increase insulin sensitivity.
Guohong, Liu, Mirta, Grifman, James, Macdonald, Peter, Moller, Flossie, Wong-Staal, Qi-Xiang, Li   +5 more
openaire   +2 more sources

Plant‐Based Anticancer Compounds With a Focus on Breast Cancer

Cancer Reports, Volume 7, Issue 10, October 2024.
ABSTRACT Breast cancer is a common form of cancer among women characterized by the growth of malignant cells in the breast tissue. The most common treatments for this condition include chemotherapy, surgical intervention, radiation therapy, hormone therapy, and biological therapy.
Amin Moradi Hasan‐Abad, Amir Atapour, Ali Sobhani‐Nasab, Hossein Motedayyen, Reza ArefNezhad   +4 more
wiley   +1 more source

Influence of Air Drying, Freeze Drying and Oven Drying on the Biflavone Content in Yellow Ginkgo (Ginkgo biloba L.) Leaves

Applied Sciences
Drying herbs is a crucial method for stabilizing and preserving their essential properties and bioactive compounds. Although freeze drying is the preferred method for most herbs, it is expensive due to high energy consumption and operating costs ...
Iva Jurčević Šangut, Lana Pavličević, Dunja Šamec   +2 more
doaj   +1 more source

Prospects for intranasal drug delivery systems with Ginkgo biloba in the treatment of cerebral circulatory disorders [PDF]

, 2021
Purpose: To analyze the range of currently available nasal medicines, and to study extant information on the use of Ginkgo biloba herbal complexes for the treatment of cerebral circulatory disorders of different etiologies.
Bokov, D.O., Bunyatyan, N.D., Evteev, V.A., Korol, L.A., Kovtun, E.V., Olefir, Yu V., Prokofiev, A.B., Samylina, I.A., Stepanova, E.F.   +8 more
core   +2 more sources

Safety and efficacy of feed additives consisting of ginkgo tinctures obtained from the leaves of Ginkgo biloba L. for use in all animal species (FEFANA asbl)

EFSA Journal, Volume 22, Issue 5, May 2024.
Abstract Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety and efficacy of tinctures obtained from the dried leaves of Ginkgo biloba L. (ginkgo tinctures) when used as sensory additives.
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP), Vasileios Bampidis, Giovanna Azimonti, Maria de Lourdes Bastos, Henrik Christensen, Mojca Durjava, Maryline Kouba, Marta López‐Alonso, Secundino López Puente, Francesca Marcon, Baltasar Mayo, Alena Pechová, Mariana Petkova, Fernando Ramos, Roberto Edoardo Villa, Ruud Woutersen, Paul Brantom, Andrew Chesson, Josef Schlatter, Johannes Westendorf, Yvette Dirven, Paola Manini, Birgit Dusemund   +22 more
wiley   +1 more source

Isoginkgetin, a potential CDK6 inhibitor, suppresses SLC2A1/GLUT1 enhancer activity to induce AMPK-ULK1-mediated cytotoxic autophagy in hepatocellular carcinoma

Autophagy, 2022
Isoginkgetin (ISO), a natural biflavonoid, exhibited cytotoxic activity against several types of cancer cells. However, its effects on hepatocellular carcinoma (HCC) cells and mechanism remain unclear. Here, we revealed that ISO effectively inhibited HCC cell proliferation and migration in vitro.
Jie Yao, Shuming Tang, Chenyan Shi, Yunzhi Lin, Lanlan Ge, Qinghua Chen, Baoru Ou, Dongyu Liu, Yuyang Miao, Qiujie Xie, Xudong Tang, Jia Fei, Guangyi Yang, Jun Tian, Xiaobin Zeng   +14 more
openaire   +2 more sources

Safety and efficacy of a feed additive consisting of a dry extract obtained from the leaves of Ginkgo biloba L. (ginkgo extract) for horses, dogs, cats, rabbits and guinea pigs (FEFANA asbl)

EFSA Journal, Volume 22, Issue 4, April 2024.
Abstract Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety and efficacy of a feed additive obtained from the dried leaves of Ginkgo biloba L. (ginkgo extract) when used as a sensory additive in feed for horses, dogs, cats, rabbits and guinea pigs.
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP), Vasileios Bampidis, Giovanna Azimonti, Maria de Lourdes Bastos, Henrik Christensen, Mojca Durjava, Maryline Kouba, Marta López‐Alonso, Secundino López Puente, Francesca Marcon, Baltasar Mayo, Alena Pechová, Mariana Petkova, Fernando Ramos, Roberto Edoardo Villa, Ruud Woutersen, Paul Brantom, Andrew Chesson, Josef Schlatter, Johannes Westendorf, Yvette Dirven, Paola Manini, Birgit Dusemund   +22 more
wiley   +1 more source

In silico studies evidenced the role of structurally diverse plant secondary metabolites in reducing SARS-CoV-2 pathogenesis

Scientific Reports, 2020
Plants are endowed with a large pool of structurally diverse small molecules known as secondary metabolites. The present study aims to virtually screen these plant secondary metabolites (PSM) for their possible anti-SARS-CoV-2 properties targeting four ...
Hariprasad Puttaswamy, Hittanahallikoppal Gajendramurthy Gowtham, Monu Dinesh Ojha, Ajay Yadav, Gourav Choudhir, Vasantharaja Raguraman, Bhani Kongkham, Koushalya Selvaraju, Shazia Shareef, Priyanka Gehlot, Faiz Ahamed, Leena Chauhan   +11 more
doaj   +1 more source

Nurturing longevity through natural compounds: Where do we stand, and where do we go?

Food Frontiers, Volume 5, Issue 2, Page 267-310, March 2024.
Abstract The revolution in aging research through the past decade has driven the progress in interventions that promote longevity. Dissection of the “old” hallmarks of aging has provided solid data for the definition of at least three “new” ones, opening avenues for the development of novel hallmark‐targeted pro‐longevity approaches.
Monika N. Todorova, Martina S. Savova, Liliya V. Mihaylova, Milen I. Georgiev   +3 more
wiley   +1 more source

The spliceosome U2 snRNP factors promote genome stability through distinct mechanisms; transcription of repair factors and R-loop processing [PDF]

, 2016
Recent whole-exome sequencing of malignancies have detected recurrent somatic mutations in U2 small nuclear ribonucleoprotein complex (snRNP) components of the spliceosome.
A Hegele, A Helmrich, AG Matera, AJ Pierce, B Adamson, C Pederiva, D Kaida, F Aymard, H Nakajima, J Sollier, J Tang, JM Santos-Pereira, JW Harbour, K O'Brien, K Skourti-Stathaki, K Skourti-Stathaki, K Yoshida, M Imielinski, M Tresini, MC Wahl, MJ Ellis, NM Shanbhag, P Beli, PA Ginno, R Xiao, RF Luco, S Matsuoka, S Xie, SE Polo, SJ Boguslawski, SM Cerritelli, V Bhatia, V Quesada, W Gan, X Li, Y Sato   +35 more
core   +1 more source