Results 81 to 90 of about 2,587,577 (305)

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Triterpenoid of avocado (Persea americana) seed and its cytotoxic activity toward breast MCF-7 and liver HepG2 cancer cells

Asian Pacific Journal of Tropical Biomedicine, 2017
Objective: To determine the structure of triterpenoid isolated from avocado seeds and the cytotoxic effect on MCF-7 and HepG2 cells. Methods: The powder sample was macerated with ethanol, followed with separation of the extract by column chromatography ...
Andi Nur Fitriani Abubakar, Suminar Setiati Achmadi, Irma Herawati Suparto   +2 more
doaj   +1 more source

Electron Impact Broadening of Isolated Ion Lines [PDF]

Electron impact broadening of isolated ion spectral ...
Griem, H. R.
core   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Streptococcal Extracellular Membrane Vesicles Are Rapidly Internalized by Immune Cells and Alter Their Cytokine Release

Frontiers in Immunology, 2020
Extracellular vesicles are membranous structures shed by almost every living cell. Bacterial gram-negative outer membrane vesicles (OMVs) and gram-positive membrane vesicles (MVs) play important roles in adaptation to the surrounding environment ...
Mina Mehanny, Mina Mehanny, Mina Mehanny, Marcus Koch, Claus-Michael Lehr, Claus-Michael Lehr, Gregor Fuhrmann, Gregor Fuhrmann   +7 more
doaj   +1 more source

A Detailed Far-Ultraviolet Spectral Atlas of O-Type Stars

, 2012
In this paper we present a spectral atlas covering the wavelength interval 930--1188A for O2--O9.5 stars using Far Ultraviolet Spectroscopic Explorer archival data.
Bashkin, Brandt, Fullerton, Gray, Howarth, Hubeny, Kaiser, Kurucz, Kurucz, Lanz, Massey, Maíz-Apellániz, Myron A. Smith, Pellerin, Penny, Piskunov, Robert, Smith, Smith Neubig, van Hoof, Walborn, Walborn, Walborn, Young, Zsargó   +24 more
core   +1 more source

Surfaces that are covered by two families of circles

, 2020
We list up to M\"obius equivalence all possible degrees and embedding dimensions of real surfaces that are covered by at least two pencils of circles, together with the number of such pencils.
Lubbes, Niels
core   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

FEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman, Anna E. Lester, Brian D. Zoltowski   +2 more
wiley   +1 more source

Generation of two induced pluripotent stem cell lines NCCSi005A and NCCSi006A from CD4+T cells of healthy individuals of Indian origin

Stem Cell Research, 2019
Human induced pluripotent stem cell-lines (iPSCs) of Indian origin NCCSi005A and NCCSi006A were established by reprogramming of CD4+T cells, isolated from the peripheral blood mononuclear cells (PBMCs) of two healthy female donors.
Mohsina Khan, Samruddhi Zende, Arun Vaidyanath, Rasika Avatade, Anjali Shiras   +4 more
doaj   +1 more source