A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins
FEBS Letters, EarlyView.We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue +6 more
wiley +1 more source
Design of Multi-Antenna System for UMTS Clamshell Mobile Phones with Ground Plane Effects Considerations [PDF]
, 2014 In this paper, the influence of the ground plane dimensions on the port-to-port isolation of two closely-spaced Universal Mobile Telecommunications System (UMTS) Planar Inverted-F Antennas (PIFAs) with and without neutralization line is first presented ...
Addaci, R. +4 more
core +2 more sources
Guaranteed Fault Detection and Isolation for Switched Affine Models
, 2017 This paper considers the problem of fault detection and isolation (FDI) for switched affine models. We first study the model invalidation problem and its application to guaranteed fault detection.
Harirchi, Farshad +2 more
core +1 more source
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
FEBS Letters, EarlyView.The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
Cell Transplantation, 2006 Early revascularization of pancreatic islet cells after transplantation is crucial for engraftment, and it has been suggested that vascular endothelial growth factor-A (VEGF-A) plays a significant role in this process.
Zoltan Mathe +8 more
doaj +1 more source
Reentry During A Pandemic: A Pilot Study of Access to Peer Support Through Technology to Reduce Social Isolation [PDF]
, 2022 Stacy C. Moak +2 more
openalex +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
One Child\u27s Story of School-experienced Isolation and Rejection [PDF]
, 2016 For twelve years of school, a tiny girl endured isolation and rejection from her peers most likely due to a physical abnormality. As the girl remembers, the educators in a small, rural school district did little to support her as she was ostracized by ...
Gresham, Gloria J, Dr.
core +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Thermal Evolution near Heat-Generating Nuclear Waste Canisters Disposed in Horizontal Drillholes
Energies, 2019 We consider the disposal of spent nuclear fuel and high-level radioactive waste in horizontal holes drilled into deep, low-permeable geologic formations using directional drilling technology.
Stefan Finsterle +4 more
doaj +1 more source