Results 1 to 10 of about 161,115 (245)

Titration of dietary isoleucine and evaluation of branched-chain amino acid levels in female Cobb 500 broilers during a 22- to 42-day finisher period [PDF]

Journal of Applied Poultry Research, 2022
SUMMARY: Recent research into the branched-chain amino acids has indicated that broiler responses to dietary isoleucine may vary from classic data. Current isoleucine data has focused on male broilers leaving a gap in the literature for female data.
C.W. Maynard, G.J. Mullenix, C.J. Maynard, S.C. Wells-Crafton, J.T. Lee, S.K. Rao, L.D. Butler, S.K. Orlowski, M.T. Kidd   +8 more
doaj   +3 more sources

Kinetic proofreading at single molecular level: Aminoacylation of tRNA^{Ile} and the role of water as an editor [PDF]

, 2013
Proofreading/editing in protein synthesis is essential for accurate translation of information from the genetic code. In this article we present a theoretical investigation of efficiency of a kinetic proofreading mechanism that employs hydrolysis of the wrong substrate as the discriminatory step in enzyme catalytic reactions. We consider aminoacylation
Bagchi, Biman, Santra, Mantu
arxiv   +5 more sources

NMR-based assignment of isoleucine vs allo-isoleucine stereochemistry [PDF]

Organic & Biomolecular Chemistry, 2017
A simple 1H and 13C NMR spectrometric analysis is demonstrated that permits differentiation of isoleucine and allo-isoleucine residues by inspection of the chemical shift and coupling constants of the signals associated with the proton and carbon at the ...
Anderson, Zoe J., Fox, David J., Hobson, Christian, Kerby, Paul D., Needley, Rebecca, Perryman, Michael S., Song, Lijiang   +6 more
core   +4 more sources

tRNA-isoleucine-tryptophan Composite Gene [PDF]

Biochemical and biophysical Research Communications 339 (2005) 37-40, 2005
Transfer-RNA genes in archaea often have introns intervening between exon sequences. The structural motif at the boundary between exon and intron is the bulge-helix-bulge. Computational investigations of these boundary structures in H. marismortui lead us to propose that tRNA-isoleucine and tRNA-tryptophan genes are co-located.
Harmeet Singh Sethi, Bibekanand Mallick, Jayprokas Chakrabarti, Satyabrata Sahoo, Smarajit Das, Zhumur Ghosh   +5 more
arxiv   +5 more sources

Circulating branched-chain amino acids and the risk of major adverse cardiovascular events in the UK biobank. [PDF]

Front Endocrinol (Lausanne)
ObjectiveTo investigate the relationship between circulating branched-chain amino acids (BCAAs) and the risk of major adverse cardiovascular events (MACE) in a national population-based cohort study.MethodsUK Biobank, a prospective study involving 22 ...
Sun W, Lin R, Li Y, Yao Y, Lu B, Yu Y.
europepmc   +2 more sources

Three phases in the evolution of the standard genetic code: how translation could get started [PDF]

arXiv, 2007
A primordial genetic code is proposed, having only four codons assigned, GGC meaning glycine, GAC meaning aspartate/glutamate, GCC meaning alanine-like and GUC meaning valine-like. Pathways of ambiguity reduction enlarged the codon repertoire with CUC meaning leucine, AUC meaning isoleucine, ACC meaning threonine-like and GAG meaning glutamate ...
van der Gulik, Peter
arxiv   +4 more sources

Isoleucine-to-valine substitutions support cellular physiology during isoleucine deprivation. [PDF]

Nucleic Acids Res
Abstract Aminoacyl-tRNA synthetases (ARSs) couple tRNAs with their corresponding amino acids. While ARSs can bind structurally similar amino acids, extreme specificity is ensured by subsequent editing activity. Yet, we found that upon isoleucine (I) restriction, healthy fibroblasts consistently incorporated valine (V) into proteins at ...
Kok G, Schene IF, Ilcken EF, Alcaraz PS, Mendes MI, Smith DEC, Salomons G, Shehata S, Jans JJM, Maroofian R, Hoek TA, van Es RM, Rehmann H, Nieuwenhuis EES, Vos HR, Fuchs SA.   +15 more
europepmc   +2 more sources

Studies on the the Isoleucine Fermentation

Agricultural and Biological Chemistry, 1962
Accumulation of L-isoleucine and L-valine was studied on 14 genera, 47 species and 110 strains of aerobic bacteria using bacterial type cultures. A large amount of L-isoleucine and a small amount of L-valine accumulated when 1% of DL-α-aminobutyric acid was added to the culture medium.
Masaya Hayashibe, Toshihiko Watanabe
openalex   +4 more sources

Isoleucine Enhanced the Function of the Small Intestinal Mucosal Barrier in Weaned Piglets to Alleviate Rotavirus Infection. [PDF]

Animals (Basel)
Background: Rotavirus (RV) is a major cause of diarrhea in young children and animals, especially piglets, leading to substantial economic losses in the global pig industry.
Zhao R, Jiang C, Yuan Y, Zhang S, Ghonaim AH, Che C, Li X, Jin M, Jin E, Zeng X, Li S, Ren M.   +11 more
europepmc   +2 more sources

l-Isoleucine Administration Alleviates DSS-Induced Colitis by Regulating TLR4/MyD88/NF-κB Pathway in Rats

Frontiers in Immunology, 2022
Inflammatory bowel disease (namely, colitis) severely impairs human health. Isoleucine is reported to regulate immune function (such as the production of immunoreactive substances).
Xiangbing Mao, Xiangbing Mao, Xiangbing Mao, Xiangbing Mao, Rui Sun, Rui Sun, Rui Sun, Rui Sun, Qingxiang Wang, Qingxiang Wang, Qingxiang Wang, Qingxiang Wang, Daiwen Chen, Daiwen Chen, Daiwen Chen, Daiwen Chen, Bing Yu, Bing Yu, Bing Yu, Bing Yu, Jun He, Jun He, Jun He, Jun He, Jie Yu, Jie Yu, Jie Yu, Jie Yu, Junqiu Luo, Junqiu Luo, Junqiu Luo, Junqiu Luo, Yuheng Luo, Yuheng Luo, Yuheng Luo, Yuheng Luo, Hui Yan, Hui Yan, Hui Yan, Hui Yan, Jianping Wang, Jianping Wang, Jianping Wang, Jianping Wang, Huifen Wang, Huifen Wang, Huifen Wang, Huifen Wang, Quyuan Wang, Quyuan Wang, Quyuan Wang, Quyuan Wang   +51 more
doaj   +1 more source