Results 91 to 100 of about 197,005 (375)

Three phases in the evolution of the standard genetic code: how translation could get started [PDF]

open access: yes, 2007
A primordial genetic code is proposed, having only four codons assigned, GGC meaning glycine, GAC meaning aspartate/glutamate, GCC meaning alanine-like and GUC meaning valine-like.
van der Gulik, Peter
core   +1 more source

Crystallization of L‐Cysteine in Heavy Water Induces Intrinsic Fluorescence

open access: yesAngewandte Chemie, EarlyView.
Crystallization of L‐Cysteine in D2O${\rm D}_2{\rm O}$ generates a remarkably different structure compared to H2O${\rm H}_2{\rm O}$. The crystals formed in D2O${\rm D}_2{\rm O}$ display enhanced intrinsic fluorescence, and using state‐of‐the‐art excited state simulations, we determine the molecular origins of this luminescence and propose design ...
Debarshi Banerjee   +10 more
wiley   +2 more sources

Response of piglets to the standardized ileal digestible isoleucine, histidine and leucine supply in cereal–soybean meal-based diets

open access: yesAnimal, 2013
Improving the amino acid (AA) profile of the diet by using l-Lys, l-Thr, dl-Met, l-Trp and l-Val helps to reduce the dietary CP content, thereby reducing nitrogen excretion while maintaining the performance of pigs.
M. Gloaguen   +4 more
doaj  

Molecular Simulation of the Separation of Isoleucine Enantiomers by β-Cyclodextrin

open access: yesMolecules, 2019
Molecular mechanics and dynamics simulations were carried out to study the capacity of isoleucine enantiomers to form inclusion complexes with β–cyclodextrin, and to be discriminated by this chiral compound, in vacuo and with different ...
Elena Alvira
doaj   +1 more source

Mechanisms and kinetic assays of aminoacyl‐tRNA synthetases

open access: yes
FEBS Letters, EarlyView.
Igor Zivkovic   +2 more
wiley   +1 more source

Microbiome Single Cell Atlases Generated with a Commercial Instrument

open access: yesAdvanced Science, EarlyView.
Single cell sequencing is valuable for dissecting complex systems and uncovering unique features in individual cell types. However, tools for single cell microbial analysis are limited. Easily Accessible Single microbe sequencing (EASi‐seq), which adapts a commercially available single cell platform for efficient sequencing of single microbial genomes ...
Xiangpeng Li   +8 more
wiley   +1 more source

Incorporation of unsaturated isoleucine analogues into proteins in vivo [PDF]

open access: yes, 2002
The translational activity of various unsaturated analogs of L-isoleucine was evaluated using an Escherichia coli strain auxotrophic for isoleucine. It was observed that the alkene [2-amino-3-methyl-4-pentenoic acid (2)] and alkyne [2-amino-3-rnethyl-4 ...
Barbot, Francis   +2 more
core  

Cooperative Photometallobiocatalysis: Nonheme Fe Enzyme‐Catalyzed Enantioconvergent Radical Decarboxylative Azidation, Thiocyanation, and Isocyanation of Redox‐Active Esters

open access: yesAngewandte Chemie, EarlyView.
Through the directed evolution of an underexploited nonheme Fe extradiol dioxygenase, we developed a unified cooperative photobiocatalytic strategy to allow for three types of enantioconvergent radical transformations, including azidation, thiocyanation, and isocyanation.
Liu‐Peng Zhao   +8 more
wiley   +2 more sources

Real-Time Optical Detection of Isoleucine in Living Cells through a Genetically-Encoded Nanosensor

open access: yesSensors, 2019
Isoleucine is one of the branched chain amino acids that plays a major role in the energy metabolism of human beings and animals. However, detailed investigation of specific receptors for isoleucine has not been carried out because of the non ...
Shruti Singh   +5 more
doaj   +1 more source

Impact of second line limiting amino acids’ deficiency in broilers fed low protein diets with rapeseed meal and de-oiled rice bran [PDF]

open access: yesVeterinary World, 2015
Aim: To study the impact of deficiency of second line limiting amino acids (SLAA; valine, isoleucine and tryptophan) on the production performance and carcass characteristics of commercial broilers.
C. Basavanta Kumar   +6 more
doaj   +1 more source

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