Results 101 to 110 of about 197,005 (375)

The Oxylipin Signal Jasmonic Acid Is Activated by an Enzyme That Conjugates It to Isoleucine in Arabidopsis

The Plant Cell Online, 2004
Despite its importance in a variety of plant defense responses, our understanding of how jasmonic acid (JA) functions at the biochemical level is limited.
P. Staswick, I. Tiryaki
semanticscholar   +1 more source

LincNEAT1 Encoded‐NEAT1‐31 Promotes Phagocytosis by Directly Activating the Aurora‐A–PI3K–AKT Pathway

Advanced Science, EarlyView.
LincNEAT1 Encoded‐NEAT1‐31 micropeptide directly binds with Aurora‐A and enhanced AKT pathways to pormotes phagocytosis against multi cancer cells. Abstract Macrophages play vital roles in innate and adaptive immunity, and their essential functions are mediated by phagocytosis and antigen presentation.
Jie Li, Jing Zhang, Xixi Li, Xin Liu, Bo Zeng, Jiayue Luo, Huijin Wang, Hanbing Zhang, Xinya Gao   +8 more
wiley   +1 more source

Change of Indices of the Amino Acid Composition of Rats' Hearts at Artificial Hypobiosis [PDF]

, 2019
A series of unsolved questions in such sciences as: medicine, veterinary, biology still exist in the modern world. One of them is a search for new promising ways of anaesthetization, at which it would be unnecessary to use apparatuses as an “artificial ...
Umanska, A. (Anna)
core   +3 more sources

Low-protein diets supplemented with isoleucine alleviate lipid deposition in broilers through activating 5′ adenosine monophosphate-activated protein kinase and janus kinase 2/signal transducer and activator of transcription 3 signaling pathways

Poultry Science, 2023
: This study aimed to evaluate the effect of isoleucine (Ile) on growth performance, meat quality and lipid metabolism of broilers fed a low-protein diet (LPD).
Shengnan Ma, Kai Zhang, Shuyan Shi, Xuemin Li, Chuanyan Che, Peng Chen, Huawei Liu   +6 more
doaj  

Molecular basis of various forms of maple syrup urine disease in Chilean patients

Molecular Genetics & Genomic Medicine, 2021
Background Maple syrup urine disease (MSUD) is an autosomal recessive inherited metabolic disorder caused by the deficient activity of the branched‐chain α‐keto acid dehydrogenase (BCKD) enzymatic complex.
Diana Ruffato Resende Campanholi, Ana Vitoria Barban Margutti, Wilson A. Silva Jr, Daniel F. Garcia, Greice A. Molfetta, Adriana A. Marques, Ida Vanessa Döederlein Schwartz, V. Cornejo, Valerie Hamilton, Gabriela Castro, Fernanda Sperb‐Ludwig, Ester S. Borges, José S. Camelo Jr   +12 more
doaj   +1 more source

JA‐Mediated Regulation of Amino Acid Homeostasis Adjusts Metabolic Flux and Enhances Spider Mite Tolerance via the SlJAZ8‐SlWRKY57‐SlAVT6s Module in Tomato

Advanced Science, EarlyView.
This study elucidates a novel SlJAZ8‐SlWRKY57‐SlAVT6A/SlAVT6B module that effectively channels metabolic flux from primary to secondary metabolism, impacting plant growth, development, and resistance. Two novel vacuolar amino acid exporters, SlAVT6A and SlAVT6B, fine‐tunes trichomes, terpenes, and gibberellins, bolstering spider mite resistance.
Yingchen Hao, Xiaolong Wang, Langchen Guo, Lijun Xiang, Enxi Luo, Peng Cao, Penghui Liu, Yue Zhong, Chun Li, Jun Lai, Jun Yang, Shouchuang Wang   +11 more
wiley   +1 more source

Antimitotic action of cornin as a biologically active polypeptide. I. Biochemical properties of cornin [PDF]

, 1965
We succeeded in the extraction of a substance from beef cornea and rabbit muscle, that markedly inhibits mitosis of sea urchin eggs. The substance extracted from beef cornea is non-dialysable and it can be separated into three fractions by DEAE-cellulose
Murakami, Tetuhide H., Nisida, Isamu
core   +1 more source

Effect of Intravenous L-Isoleucine Infusion upon Concentration of Free Isoleucine in Milk

Journal of Dairy Science, 1976
The growth of Streptococcus agalactiae in milk is inhibited by elevated free isoleucine. Free amino acid concentrations in both plasma and milk from three lactating dairy cows were studied after intravenous infusions of L-isoleucine at 62, 300, 380, and 840 mumol/kg of body weight. Free isoleucine was lower in milk than in plasma.
Richard W. Brown, Milton J. Allison, Ovidiu Popescu   +2 more
openaire   +3 more sources

Optimization of carbon source and glucose feeding strategy for improvement of L-isoleucine production by Escherichia coli

Biotechnology, biotechnological equipment, 2015
Fed-batch cultivations of L-isoleucine-producing Escherichia coli TRFP (SGr, α-ABAr, with a pTHR101 plasmid containing a thr operon and ilvA) were carried out on different carbon sources: glucose, sucrose, fructose, maltose and glycerol.
Jian Wang, Bingxin Wen, Qing-yang Xu, Xixian Xie, N. Chen   +4 more
semanticscholar   +1 more source

Integrated Transcriptome and Metabolomics Analyses Show MYC as a Potential Therapeutic Target for Behçet's Uveitis

Advanced Science, EarlyView.
Integrated single‐cell transcriptomic and metabolomic analyses reveal that MYC‐driven glycolysis activates the PI3K‐AKT‐FOXO1 pathway, disrupting Th17/Treg balance and promoting uveitis. MYC inhibition restores immune homeostasis and alleviates disease symptoms.
He Li, Lei Zhu, Zhaohuai Li, Yihan Zhang, Genxian Zhang, Xuening Peng, Dongting Wu, Qi Jiang, Rong Wang, Renbing Jia, Song Guo Zheng, Wenru Su   +11 more
wiley   +1 more source