Results 11 to 20 of about 183,864 (337)

Investigating the causal association between branched-chain amino acids and Alzheimer's disease: A bidirectional Mendelian randomized study

Frontiers in Nutrition, 2023
BackgroundThere are many metabolic pathway abnormalities in Alzheimer's disease (AD). Several studies have linked branched-chain amino acid (BCAA) metabolism disorders with AD but have not obtained consistent results.
Xiao-hang Qian, Xiao-hang Qian, Xiao-hang Qian, Xiao-li Liu, Bin Zhang, Yuan Lin, Jian-hua Xu, Gang-yu Ding, Hui-dong Tang, Hui-dong Tang, Hui-dong Tang   +10 more
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Computer quantum chemical modeling of the interaction of calcium phosphate with amino acids

Физико-химические аспекты изучения кластеров, наноструктур и наноматериалов, 2022
In this work, a quantum-chemical modeling of the process of interaction of calcium phosphate with amino acids was carried out. Within the framework of the quantum chemical modeling, the total energy of the molecular complex E, the energy difference ...
A.A. Blinova, A.V. Blinov, M.A. Pirogov, D.G. Maglakelidze, A.A. Yakovenko   +4 more
doaj   +1 more source

Low-protein diets supplemented with isoleucine alleviate lipid deposition in broilers through activating 5′ adenosine monophosphate-activated protein kinase and janus kinase 2/signal transducer and activator of transcription 3 signaling pathways

Poultry Science, 2023
: This study aimed to evaluate the effect of isoleucine (Ile) on growth performance, meat quality and lipid metabolism of broilers fed a low-protein diet (LPD).
Shengnan Ma, Kai Zhang, Shuyan Shi, Xuemin Li, Chuanyan Che, Peng Chen, Huawei Liu   +6 more
doaj   +1 more source

Amino acid content and biomass productivity of selected weed species as an indicator of their response to herbicide stress

Acta Agrobotanica, 2013
Biomass reduction and amino acid content in plants of Papaver rhoeas L. and Stellaria media L. were investigated to evaluate response of these species to herbicide stress under various temperature (25/16 and 8/2 oC) and relative humidity (50 and 75 ...
Renata Kieloch, Jerzy Sadowski, Krzysztof Domaradzki   +2 more
doaj   +1 more source

Variation in hemolytic activity of Brachyspira hyodysenteriae strains from pigs [PDF]

, 2016
Brachyspira hyodysenteriae is the primary cause of swine dysentery, which is responsible for major economic losses to the pig industry worldwide. The hemolytic activity of 10 B.
Boyen, Filip, De Pauw, Nele, Ducatelle, Richard, Haesebrouck, Freddy, Mahu, Maxime, Martel, An, Pasmans, Frank, Vande Maele, Lien, Verlinden, Marc   +8 more
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PNAS plus: plasmodium falciparum responds to amino acid starvation by entering into a hibernatory state [PDF]

, 2012
The human malaria parasite Plasmodium falciparum is auxotrophic for most amino acids. Its amino acid needs are met largely through the degradation of host erythrocyte hemoglobin; however the parasite must acquire isoleucine exogenously, because this ...
Baertl, Bozdech, Brennand, C. Doerig, C. Fennell, Callebaut, Codd, D. E. Goldberg, Daily, Dever, Divo, Dyer, E. S. Istvan, Fennell, Fidock, Francis, Functional Genomics Workshop Group, Harris, Hinnebusch, Hinnebusch, Kafsack, Kilberg, Kim, Kourtis, L. Altenhofen, Lambros, Llinas, Lu, Lu, M. Llinas, Olszewski, Payne, Pfaller, Roth, Russo, S. A. Cobbold, S. E. Babbitt, Sharma, Sherman, Sims, Soeters, Towbin, Trager, van Werven, Wek, Zaborske, Zolg   +46 more
core   +1 more source

Self-assembly of Alanine-Isoleucine and Isoleucine-Isoleucine Dipeptides through Atomistic Simulations and Experiments

The Journal of Physical Chemistry B, 2020
A detailed investigation of the structural and conformational properties of alanine-isoleucine (Ala-Ile) and isoleucine-isoleucine (Ile-Ile) dipeptides is presented in water and in methanol solvents. We propose a consistent combination of complementary simulation and experimental methods, covering a broad range of length and time scales, from the very ...
Anastassia N. Rissanou, Georgios Simatos, Panagiota Siachouli, Vagelis Harmandaris, Anna Mitraki   +4 more
openaire   +2 more sources

Dietary isoleucine supplementation enhances growth performance, modulates the expression of genes related to amino acid transporters and protein metabolism, and gut microbiota in yellow-feathered chickens

Poultry Science, 2023
: This study investigated the effects of dietary isoleucine (Ile) on growth performance, intestinal expression of amino acid transporters, protein metabolism-related genes and intestinal microbiota in starter phase Chinese yellow-feathered chickens ...
D. Ruan, Q.L. Fan, S. Zhang, H.K. EI-Senousey, A.M. Fouad, X.J. Lin, X.L. Dong, Y.F. Deng, S.J. Yan, C.T. Zheng, Z.Y. Jiang, S.Q. Jiang   +11 more
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Two Adjacent Phenylalanines In the NMDA Receptor GluN2A Subunit M3 Domain Interactively Regulate Alcohol Sensitivity and Ion Channel Gating [PDF]

, 2017
The N-methyl-d-aspartate (NMDA) receptor is a key target of ethanol action in the central nervous system. Alcohol inhibition of NMDA receptor function involves small clusters of residues in the third and fourth membrane-associated (M) domains.
Dwyer, Donard S., Peoples, Robert W., Ren, Hong, Wu, Man, Zhao, Yulin   +4 more
core   +2 more sources

Elucidating the importance of the catabolic enzyme, methionine-gamma-lyase, in stresses during Arabidopsis seed development and germination

Frontiers in Plant Science, 2023
The sulfur-containing essential amino acid, methionine, is a key metabolite in plant cells since it is used as a precursor for the synthesis of vital metabolites.
Yael Hacham, Yael Hacham, Odelia Shitrit, Odelia Shitrit, Ortal Nisimi, Ortal Nisimi, Meital Friebach, Meital Friebach, Rachel Amir, Rachel Amir   +9 more
doaj   +1 more source