Results 101 to 110 of about 4,732 (200)

Isoliquiritigenin Promotes the Repair of High Uric Acid‐Induced Vascular Injuries

Smart Medicine
Hyperuricemia (HUA) is a chronic metabolic disease mainly stemming from purine metabolism disorders and strongly correlated with cardiovascular diseases, gout, chronic kidney disease, and other diseases.
Hongyan Zhou, Xinyu Song, Yingying Tian, Lili Zhao, Jingyi Yang, Fangfu Ye, Ting Cao, Jiayu Zhang   +7 more
doaj   +1 more source

ISL Induces Apoptosis and Autophagy in Hepatocellular Carcinoma via Downregulation of PI3K/AKT/mTOR Pathway in vivo and in vitro

Drug Design, Development and Therapy, 2020
Lei Song,1,2 Yi Luo,1 Shaoling Li,2 Ming Hong,1 Qi Wang,1 Xiaoling Chi,2 Cong Yang1 1Science and Technology Innovation Center, Guangzhou University of Chinese Medicine, Guangzhou 510405, People’s Republic of China; 2The Second Affiliated Hospital ...
Song L, Luo Y, Li S, Hong M, Wang Q, Chi X, Yang C   +6 more
doaj  

Additional file 2: of Inhibition of COX-2, mPGES-1 and CYP4A by isoliquiritigenin blocks the angiogenic Akt signaling in glioma through ceRNA effect of miR-194-5p and lncRNA NEAT1

, 2019
Figure S1.
Chenlong Wang (6371420), Xiaoxiao Liu (671993), Yang Wang (5921), Honglei Chen (125181), Yanzhuo Liu (5437304), Yaxin Chen (1461961), Ying Li (38224), Jing Yang (13969), Chengpeng Fan (2040829), Dongfang Wu (585045)   +9 more
core   +1 more source

Isoliquiritigenin Attenuates UUO-Induced Renal Inflammation and Fibrosis by Inhibiting Mincle/Syk/NF-Kappa B Signaling Pathway

Drug Design, Development and Therapy, 2020
Yuan Liao,1,* Rui-zhi Tan,1,* Jian-chun Li,1 Tong-tong Liu,1 Xia Zhong,1 Ying Yan,1 Jie-ke Yang,1 Xiao Lin,1 Jun-ming Fan,2 Li Wang1 1Research Center of Combine Traditional Chinese and Western Medicine, Affiliated Traditional Medicine Hospital, Southwest
Liao Y, Tan R, Li J, Liu T, Zhong X, Yan Y, Yang J, Lin X, Fan J, Wang L   +9 more
doaj  

Isoliquiritigenin Alleviates Periodontitis by Suppressing Inflammation via NF-κB Signaling Pathway of Immune Cell

Xiao Wang,1,2,* Tianliang Zhao,2,3,* Biling Liang,1 Jing Fang,4 Qiu Dong,5 Qianqian Chen1,2 1Department of Stomatology, The First Affiliated Hospital of Guangxi University of Science and Technology, Guangxi University of Science and ...
Chen Q, Fang J, Wang X, Zhao T, Dong Q, Liang B   +5 more
core  

Isoliquiritigenin ameliorates abnormal oligodendrocyte development and behavior disorders induced by white matter injury

Frontiers in Pharmacology
BackgroundWhite matter injury is a predominant form of brain injury in preterm infants. However, effective drugs for its treatment are currently lacking.
Dong Wu, Dong Wu, Wenjuan Zhou, Jingyi Du, Tiantian Zhao, Naigang Li, Fan Peng, Anna Li, Xinyue Zhang, Meihua Zhang, Aijun Hao, Aijun Hao   +11 more
doaj   +1 more source

Long-Circulating and Brain-Targeted Liposomes Loaded with Isoliquiritigenin: Formation, Characterization, Pharmacokinetics, and Distribution

Pharmaceutics
Isoliquiritigenin (ISL) has excellent neuroprotective effects. However, its limitations, including poor solubility, low bioavailability, and low accumulation in the brain, restrict its clinical promotion.
Weitong Song, Lu Bai, Pingxiang Xu, Yuming Zhao, Xuelin Zhou, Jie Xiong, Xiaorong Li, Ming Xue   +7 more
doaj   +1 more source

Uji sitotoksik, toksisitas dan prediksi sifat fisikokimia senyawa isoliquiritigenin dan oxyresveratrol terhadap Reseptor B-cell lymphoma 2 (4AQ3) dan Vascular Endothelial Growth Factor Receptor-2 (2RL5) sebagai terapi Kanker Serviks secara in silico [PDF]

, 2019
INDONESIA: Isoliquiritigenin dan oxyresveratrol merupakan senyawa yang telah dilaporkan memiliki aktivitas antikanker. Pertumbuhan sel kanker sering dikaitkan dengan overekspresi B-cell lymphoma 2 (BCL-2) sehingga akan menyebabkan kemampuan apoptosis ...
Hariz, Muhammad Fawwaz
core  

Design, Synthesis, and Antitumor Activity of Isoliquiritigenin Amino Acid Ester Derivatives

Isoliquiritigenin (ISL) is a chalcone that has shown great potential in the treatment of cancer. However, its relatively weak activity and low water solubility limit its clinical application. In this study, we designed and synthesized 21 amino acid ester
Qing Ma, Enbo Cai, Chi Liu, Xinyue Liu, Fengyan Su   +4 more
core   +1 more source

Recent advances in structural modification and biological activities of isoliquiritigenin and liquiritigenin. [PDF]

RSC Adv
He S, Du C, Liu J, Wei S, Wang Z.
europepmc   +1 more source