Results 91 to 100 of about 4,732 (200)

IGFBP5 mediates the therapeutic effect of isoliquiritigenin in myocardial ischemia-reperfusion injury via AKT/GLUT4 regulated insulin resistance

Frontiers in Pharmacology
BackgroundMyocardial ischemia/reperfusion injury (MIRI) is a critical problem in cardiovascular medicine, often occurring after coronary revascularization procedures or cardiopulmonary bypass.
Jue Bai, Jue Bai, Si-Yuan Yang, Shao-Mei Yu, Ying Cao, Chang-Han Ma, Chang-Han Ma, Xuan-Yi Hu, Xiong Chen, Ying-Nan Song, Ying-Nan Song, Hong-Jin Chen, Hong-Jin Chen, Hong-Jin Chen   +13 more
doaj   +1 more source

Reinvestigation of the synthesis of isoliquiritigenin: application of Horner-Wadsworth-Emmons reaction and Claisen-Schmidt condensation.

, 2011
Isoliquiritigenin [ILG, (E)-1] was readily prepared via the Horner-Wadsworth-Emmons reactions using β-ketophosphonates 5a, b.
Yoshinori Okubo, Nagao, Y, Kakegawa, H, Atsushi Handa, Okubo, Y, Nakao, M, Michiyasu Nakao, Shigeki Sano, Syuji Kitaike, Handa, A, Hisao Kakegawa, Yoshimitsu Nagao, Sano, S, Kitaike, S   +13 more
core   +1 more source

Production of Sinorhizobium meliloti nod Gene Activator and Repressor Flavonoids from Medicago sativa Roots

Molecular Plant-Microbe Interactions, 1998
During symbiosis between leguminous plants and rhizobia, flavonoids exuded by the plants act as chemoattractants and nodulation (nod) gene regulators in the other partner.
José Angelo Silveira Zuanazzi, Pierre Henri Clergeot, Jean-Charles Quirion, Henri-Philippe Husson, Adam Kondorosi, Pascal Ratet   +5 more
doaj   +1 more source

Dynamic Residual Complexity of the Isoliquiritigenin–Liquiritigenin Interconversion During Bioassay

, 2016
Bioactive components in food plants can undergo dynamic processes that involve multiple chemical species. For example, 2′-hydroxychalcones can readily isomerize into flavanones.
Guido F. Pauli (1235025), David C. Lankin (1235037), Shao-Nong Chen (1235046), Charlotte Simmler (1235040), Tristesse Jones (1984936), Judy L. Bolton (194650), Atieh Hajirahimkhan (433361), Djaja D. Soejarto (1310769)   +7 more
core   +1 more source

Isoliquiritigenin Induces Growth Inhibition and Apoptosis Through Downregulating Arachidonic Acid Metabolic Network and the Deactivation of PI3K/Akt in Human Breast Cancer

, 2013
Arachidonic acid (AA)-derived eicosanoids and its downstream pathways have been demonstrated to play crucial roles in growth control of breast cancer. Here, we demonstrate that isoliquiritigenin, a flavonoid phytoestrogen from licorice, induces growth ...
Zhang, Jing, Li, Ying, Zheng, Hao, Falck, John R, Yu, Wei, Guo, Austin M, Yue, Jiang, Yang, Jing, Chai, Hongyan, Peng, Renxiu, Zhao, Haixia, Wang, Yuzhong   +11 more
core   +1 more source

Protective Effects of Isoliquiritigenin Against Methamphetamine-Induced Neurotoxicity in Mice

, 2009
Isoliquiritigenin (ISL) suppresses cocaine-induced extracellular dopamine levels and has a neuroprotective effect in cocaine-treated rat brain. Here, we examine the effect of ISL on methamphetamine-induced striatal neurotoxicity.
Meeyul Hwang, Chae Ha Yang, Min Jung Lee, Jae-Pil Jeon   +3 more
core   +1 more source

Licorice Extract Isoliquiritigenin Increased Cytosol Calcium and Induced Apoptosis in Colon Cancer Cells via Transient Receptor Potential Vanilloid‐1

Cancer Medicine
Background Colorectal cancer (CRC) is the third most common malignant tumor, and the fifth cause of cancer‐related death in China, while chemotherapy is the primary strategy for CRC.
Lin Wang, Qing Li, Lai Kwok Leung, Wing Tak Wong   +3 more
doaj   +1 more source

Isoliquiritigenin Prevents the Development of Nephropathy by an HFD in Rats Through the Induction of Antioxidant Production and Inhibition of the MD-2/TLR4/NF-κB Pathway

Biology
This study tested the ISL against renal damage induced by a high-fat diet (HFD) and explored its underlying mechanisms. Adult male rats were assigned to four groups: (1) control on a standard diet (STD), (2) ISL on STD (30 mg/kg), (3) HFD, and (4) HFD ...
Mohammed Abdo Yahya, Ghedeir M. Alshammari, Magdi A. Osman, Laila Naif Al-Harbi, Setah Naif Alotaibi   +4 more
doaj   +1 more source

Experimental study on the therapeutic of isoliquiritigenin⁃fullerene gel on amiodarone⁃induced phlebitis

Huli yanjiu
ObjectiveTo investigate the therapeutic effect of isoliquiritigenin-fullerene gel on amiodarone⁃induced phlebitis.MethodsA total of 60 healthy adult rabbits were selected as research subjects.They were randomly divided into blank control group and ...
ZHANG Beilei, KE Yanqin, ZHANG Peizhe, WANG Qi, WU Jiabei, GUO Jinli   +5 more
doaj  

Abstracts

Molecular Oncology, Volume 20, Issue S1, Page 1-692, August 2026.
Abstracts submitted to the ‘EACR 2026 Congress: Innovative Cancer Science’, from 08–11 June 2026 and accepted by the Congress Organising Committee are published in this Supplement of Molecular Oncology, an affiliated journal of the European Association for Cancer Research (EACR).
wiley   +1 more source