Results 81 to 90 of about 4,732 (200)

Cytotoxic Evaluation against Breast Cancer Cells of Isoliquiritigenin Analogues from Spatholobus suberectus and Their Synthetic Derivatives

, 2016
Five isoliquiritigenin analogues, including a new methylene-bridged bischalcone (1), were isolated from Spatholobus suberectus. Cytotoxicity screening of these isolates and several synthetic derivatives indicated that the introduction, removal, position ...
Liang Xiong (1426411), Chen, J, Fu Peng (1426402), Qin-Mei Zhou (1426408), PENG, F, Jian-Ping Chen (286449), Xiong, L, Chun-Wang Meng (1426405), Meng, CW, ZHou, QM   +9 more
core   +1 more source

Isoliquiritigenin Protects Against Pancreatic Injury and Intestinal Dysfunction After Severe Acute Pancreatitis via Nrf2 Signaling

Frontiers in Pharmacology, 2018
Severe acute pancreatitis (SAP) is a digestive system disease that is associated with a range of complications including intestinal dysfunction. In this study, we determined that the chalcone compound, isoliquiritigenin (ISL), reduces pancreatic and ...
Man Zhang, Yan-Qing Wu, Ling Xie, Jiang Wu, Ke Xu, Jian Xiao, Da-Qing Chen   +6 more
doaj   +1 more source

Development and Functional Evaluation of a Pharmabiotic Food Supplement Containing Microencapsulated Lactiplantibacillus pentosus for Oral Microbiome Health

Food Science &Nutrition, Volume 14, Issue 8, August 2026.
Development of a multifunctional pharmabiotic oral spray containing microencapsulated Lactiplantibacillus pentosus, hyaluronic acid, and Glycyrrhiza glabra extract. The formulation synergistically suppresses oral biofilms while exhibiting antimicrobial and antioxidant activities, supporting oral microbiome homeostasis.
Pervin Soyer, A. Alper Öztürk
wiley   +1 more source

Synthesis and Anti-Tumor Activity of Novel Aminomethylated Derivatives of Isoliquiritigenin

, 2014
A series of new aminomethylated derivatives of isoliquiritigenin was synthesized. The structures of the compounds were confirmed by IR, MS, NMR, 13C-NMR and elemental analyses.
Haoran Fu, Thomas Efferth, Yuhang Zhang, Xiqing Wang, Yujie Fu, Yingzhi Han, Xiao Peng   +6 more
core   +1 more source

Long-Circulation and Brain Targeted Isoliquiritigenin Micelle Nanoparticles: Formation, Characterization, Tissue Distribution, Pharmacokinetics and Effects for  Ischemic Stroke

International Journal of Nanomedicine, 2022
Weitong Song,1 Lu Bai,1 Yuya Yang,1 Yongchao Wang,2 Pingxiang Xu,1,3 Yuming Zhao,1 Xuelin Zhou,1,3 Xiaorong Li,1,3 Ming Xue1,3 1Department of Pharmacology, School of Basic Medical Sciences, Capital Medical University, Beijing, People’s Republic of China;
Song W, Bai L, Yang Y, Wang Y, Xu P, Zhao Y, Zhou X, Li X, Xue M   +8 more
doaj  

Isoliquiritigenin induces apoptosis by depolarizing mitochondrial membranes in prostate cancer cells

, 2006
Isoliquiritigenin (ISL), a simple chalcone derivative, 4,2′,4′-trihydroxychalcone, found in licorice, shallot and bean sprouts, has been reported to have chemoprotective effects.
박광균, 정원윤
core   +1 more source

Targeted delivery of isoliquiritigenin by ultrasonic microbubbles attenuate myocardial injury via suppressing inflammation and oxidative stress and activating AMPK/SIRT1/eNOS signaling pathway in rats

, 2023
To investigate the protective efficacy of ultrasound targeted microbubble destruction (UTMD) combined with Isoliquiritigenin on myocardial injury in rats.
Lijing Zhang, Shuang Liang, Shanshan Liang   +2 more
core   +1 more source

Differentiation-inducing and anti-proliferative activities of isoliquiritigenin and all-trans-retinoic acid on B16F0 melanoma cells: Mechanisms profiling by RNA-seq [PDF]

, 2016
Melanoma is a cancer that arises from melanocytes, specialized pigmented cells that are found predominantly in the skin. The incidence of malignant melanoma has significantly increased over the last decade.
Chen, XY, Zheng, QS, Yang, M, Hao, WJ, Sun, SG, Han, JC, Ma, J, Wang, CX, Zheng, QS (reprint author), Binzhou Med Univ, Yantai 264003, Shandong, Peoples R China., Sun, SG (reprint author), Northwest A&F Univ, Yangling 712100, Peoples R China. Email:sunsg@nwsuaf.edu.cn, zqsyt@sohu.com   +10 more
core   +1 more source

Mechanisms of Triptolide-Induced Hepatotoxicity and Protective Effect of Combined Use of Isoliquiritigenin: Possible Roles of Nrf2 and Hepatic Transporters

Frontiers in Pharmacology, 2018
Triptolide (TP), the main bioactive component of Tripterygium wilfordii Hook F, can cause severe hepatotoxicity. Isoliquiritigenin (ISL) has been reported to be able to protect against TP-induced liver injury, but the mechanisms are not fully elucidated.
Zhenyan Hou, Zhenyan Hou, Lei Chen, Lei Chen, Pingfei Fang, Pingfei Fang, Hualin Cai, Hualin Cai, Huaibo Tang, Yongbo Peng, Yang Deng, Lingjuan Cao, Lingjuan Cao, Huande Li, Huande Li, Bikui Zhang, Bikui Zhang, Miao Yan, Miao Yan   +18 more
doaj   +1 more source

Isoliquiritigenin induces caspase-dependent apoptosis via downregulation of HPV16 E6 expression in cervical cancer Ca Ski cells.

, 2013
International audienceFlavonoids have antitumoral properties and may be attractive candidates as anticancer therapy. Isoliquiritigenin which is a constituent of licorice (Glycyrrhiza inflata), a plant commonly used in traditional Uyghur medicine in ...
Mougin, Christiane, Ablise, Mourboul, Hirchaud, Fabienne, Fauconnet, Sylvie, Vuitton, Dominique, Hermetet, François, Pretet, Jean-Luc   +6 more
core   +1 more source