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The antioxidant activity and neuroprotective mechanism of isoliquiritigenin

Free Radical Biology and Medicine, 2020
Glycyrrhizae radix has been widely accepted as a functional food in Asia. Isoliquiritigenin is a characteristic bioactive chemical in this medicinal plant. In this work, the neuroprotective effect of isoliquiritigenin and the possible mechanisms were investigated.
Yue-Ming Jiang, Bao Yang, Lingrong Wen
exaly   +3 more sources

Differential effects of isoliquiritigenin and YC-1 in rat aortic smooth muscle

open access: yesEuropean Journal of Pharmacology, 1997
Wegener J, Nawrath H. Differential effects of isoliquiritigenin and YC-1 in rat aortic smooth muscle. European Journal of Pharmacology. 1997;323(1):89-91.We investigated the effects of isoliquiritigenin and YC-1 (3-(5′-hydroxymethyl-2′-furyl)-1-benzyl ...
Jörg W Wegener   +2 more
exaly   +2 more sources

Isoliquiritigenin Inhibits the Growth of Prostate Cancer

European Urology, 2003
Isoliquiritigenin, one of the components in the root of Glycyrrhiza glabra L., is a member of the flavonoids, which are known to have an anti-tumor activity in vitro and in vivo. In this study, we investigated the anti-tumor effect of isoliquiritigenin on prostate cancer in vitro.DU145 and LNCaP prostate cancer cell lines were used as targets.
Toshiyuki Sakai   +2 more
exaly   +3 more sources

A Review: The Pharmacology of Isoliquiritigenin

Phytotherapy Research, 2015
Isoliquiritigenin (ISL) is one of the bioactive ingredients isolated from the roots of plants belonging to licorice, including Glycyrrhiza uralensis, Mongolian glycyrrhiza, Glycyrrhiza glabra, and so forth. Liquiritigenin is available in common foods and alternative medicine, and its derivative‐ISL is applied into food additives and disease treatment ...
Cheng Peng, Hailin Tang, Jiangang Shen
exaly   +5 more sources

Effects of isoliquiritigenin on ovarian antral follicle growth and steroidogenesis [PDF]

open access: yesReproductive Toxicology, 2016
Isoliquiritigenin is a botanical estrogen used as a dietary supplement. Previous studies show that other botanical estrogens affect ovarian estradiol synthesis, but isoliquiritigenin's effects on the ovary are unknown. Thus, this study tested the hypothesis that isoliquiritigenin inhibits ovarian antral follicle growth and steroidogenesis.
Jodi A Flaws   +2 more
exaly   +3 more sources

Isoliquiritigenin Decreases Bone Resorption and Osteoclast Differentiation

Molecular Nutrition & Food Research, 2022
ScopeA dose‐ranging study is performed using young estrogen‐depleted rats to determine whether dietary isoliquiritigenin (ILQ) alters bone metabolism and if the effects are associated with estrogen receptor signaling.Methods and ResultsSix‐week‐old rats (ovariectomized at 4 weeks of age) are fed diets containing 0, 100, 250, or 750 ppm ILQ (n = 5 ...
Kaitlyn M. Joyce   +9 more
openaire   +2 more sources

Isoliquiritigenin induces G2 and M phase arrest by inducing DNA damage and by inhibiting the metaphase/anaphase transition

open access: yesCancer Letters, 2009
Isoliquiritigenin, a natural flavonoid found in licorice, shallots, and bean sprouts, has been demonstrated to inhibit proliferation and to induce apoptosis in a variety of human cancer cells.
Won-Yoon Chung   +2 more
exaly   +2 more sources

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