Results 51 to 60 of about 4,732 (200)

Antimutagenic components in Spatholobus suberectus Dunn against N-methyl-N-nitrosourea

Genes and Environment, 2019
Background An extract from Spatholobus suberectus (S. suberectus) Dunn has been reported to show potent antimutagenic effects against N-alkyl-N-nitrosoureas in umu screening.
Keiko Inami, Yoshihisa Asada, Takumi Harada, Yuta Okayama, Noriko Usui, Masataka Mochizuki   +5 more
doaj   +1 more source

Isoliquiritigenin Alleviates Semen Strychni-Induced Neurotoxicity by Restoring the Metabolic Pathway of Neurotransmitters in Rats

Frontiers in Pharmacology, 2021
Acute neurotoxicity of Semen Strychni can result in sudden death in epilepsy. The detoxification method and mechanism of Semen Strychni acute poisoning have not been clarified.
Lu Wang, Lu Wang, Min Zhang, Min Zhang, Jing Wen, Yalan Xiang, Yalan Xiang, Xiaoyu Duan, Xiaoyu Duan, Changwei Yu, Changwei Yu, Miao Yan, Miao Yan, Bikui Zhang, Bikui Zhang, Pingfei Fang, Pingfei Fang   +16 more
doaj   +1 more source

Liquiritigenin Ameliorates High‐Fat Diet‐Induced Hepatic Steatosis by Promoting Lipid Droplet Catabolism via PLIN2‐ATGL Regulation

Phytotherapy Research, EarlyView.
Liquiritigenin promotes expression of CGI‐58 and enhances lipolysis by down‐regulating expression of PLIN2, thereby facilitating the catabolism of larger‐sized lipid droplets and producing smaller‐sized lipid droplets, resulting in enhanced activity of lipophagy and ameliorated hepatic steatosis. ABSTRACT Metabolic‐associated fatty liver disease (MAFLD)
Zhuoya Xu, Jingmiao Chen, Hong Qin, Yansong Fu, Cunqi Lv, Zhipeng Wang, Xi Liu, Wenya Zheng   +7 more
wiley   +1 more source

Isoliquiritigenin, a Strong nod Gene- and Glyceollin Resistance- Inducing Flavonoid from Soybean Root Exudate [PDF]

, 1992
Isoflavonoid signal molecules from soybean (Glycine max (L.) Merr.) seed and root exudate induce the transcription of nodulation (nod) genes in Bradyrhizobium japonicum. In this study, a new compound with symbiotic activity was isolated from soybean root
Parniske, Martin, Werner, Dietrich, Brandt, Sebastian, Kape, Rüdiger   +3 more
core   +1 more source

Plant‐Derived Natural Product Nanodelivery System in Cancer Therapy

Phytotherapy Research, EarlyView.
This review comprehensively summarizes the recent progress and emerging concepts in nanotechnology‐based delivery systems for plant‐derived natural products, with a particular focus on their application in precision cancer therapy. ABSTRACT Plant‐derived natural products have emerged as important sources of anticancer agents because of their diverse ...
Changqi Shi, LuLu Zhang, Lan Yan, Qi Geng, Li Li, Xiaojuan He, Ning Zhao, Yong Tan, Xiaomeng Zhang, Cheng Lu   +9 more
wiley   +1 more source

Computer-aided Discovery of Bioactive Natural Product Isoliquiritigenin as an Acetylcholinesterase Inhibitor [PDF]

Bioactive natural products have been extensively investigated for the discovery of alternative Alzheimer’s disease (AD) treatments. Recently, our structure-based virtual screening (SBVS) campaigns on natural products served in the LOTUS database ...
Istyastono, Enade Perdana, Riswanto, Florentinus Dika Octa, Waskitha, Stephanus Satria Wira, Gani, Michael Raharja   +3 more
core   +1 more source

Synthetic Isoliquiritigenin Inhibits Human Tongue Squamous Carcinoma Cells through Its Antioxidant Mechanism [PDF]

, 2017
© 2017 Cuilan Hou et al. Isoliquiritigenin (ISL), a natural antioxidant, has antitumor activity in different types of cancer cells. However the antitumor effect of ISL on human tongue squamous carcinoma cells (TSCC) is not clear.
Yang, Y., Hou, C., Li, W., Chen, Z., Li, Z., Song, Yong, Gao, J., Zhang, X., Zhao, X.   +8 more
core   +3 more sources

Isoliquiritigenin Ameliorates Ischemia-Induced Myocardial Injury via Modulating the Nrf2/HO-1 Pathway in Mice

Drug Design, Development and Therapy, 2022
Deshan Yao,1,2 Bo Shi,3 Sichuan Wang,1,2 Liuxiang Bao,1,2 Meng Tan,1,2 Hui Shen,1,2 Zhengang Zhang,1,2 Xin Pan,1,2 Yi Yang,1,2 Yong Wu,1,2 Kaizheng Gong1,2 1Department of Cardiology, the Affiliated Hospital of Yangzhou University, Yangzhou University ...
Yao D, Shi B, Wang S, Bao L, Tan M, Shen H, Zhang Z, Pan X, Yang Y, Wu Y, Gong K   +10 more
doaj  

Natural Products Exhibit Therapeutic Potential in Treating Rheumatoid Arthritis by Targeting the PI3K/Akt Signaling Pathway

Phytotherapy Research, EarlyView.
This review summarizes how natural products, mainly including flavonoids, terpenoids, alkaloids, and polyphenols alleviate RA via PI3K/Akt pathway, regulating inflammation, proliferation, apoptosis, angiogenesis, and osteoclast differentiation. The figure was created by Figdraw (https://www.figdraw.com/#/).
Haishuo Ren, Yige Wang, Wenjing Ma, Omachi Daniel Ogaji, Shujing Chen, Kunze Du, Xuemi Zhang, Bo Xu, Shanxing Zhai, Shiming Fang, Yanxu Chang   +10 more
wiley   +1 more source

Plant‐Derived Extracellular Vesicles: Biogenesis, Function, and Application in Cancer Immunotherapy

Phytotherapy Research, EarlyView.
This illustration shows the biogenesis pathways of edible and medicinal plant‐derived extracellular vesicles (PDEVs) and their therapeutic effects following uptake in the human body, highlighting their potential for application in cancer immunotherapy. ABSTRACT Plant‐derived extracellular vesicles (PDEVs) are nanoscale, lipid bilayer‐enclosed vesicles ...
Guosheng Li, Mengyu Li, Shujing Liu, Yuan Wei, Chen Wang   +4 more
wiley   +1 more source