Results 231 to 240 of about 12,847 (298)

It started off as a Cys, how did it end up like this? Identifying the extent of unmodelled oxidatively modified cysteines within the Protein Data Bank

Acta Crystallographica Section D, Volume 82, Issue 7, Page 700-714, July 2026.
This work examines data contained within 118 215 structures in the Protein Data Bank for unmodelled difference density concomitant with unmodelled oxidatively damaged cysteines. This analysis demonstrates that site‐specific oxidation of residues is a phenomenon of which the experimenter should be aware, and highlights the need for a suitable detection ...
Samuel P. Foster, Anna J. Warren, C. Alistair Siebert, Jaswir Basran, Peter C. E. Moody   +4 more
wiley   +1 more source

Protein disulfide isomerases regulate androgen receptor stability and promote prostate cancer cell growth and survival. [PDF]

Proc Natl Acad Sci U S A
Xie J, Shen K, Liang W, Kuang Z, Shrestha RK, Hanson AR, Townley SL, He M, Yu S, Zhou P, Zhu L, Gong Z, Ao X, Rao SR, Zhang Q, Chen K, Wei J, Marri S, Snel MF, Irani S, Chen L, Wang L, McDougal DP, Bruning JB, Ou M, Wang S, Proud CG, Du H, Butler LM, Selth LA.   +29 more
europepmc   +1 more source

Multi‐Omics Profiling of the Scaphoideus titanus Yeast‐Like Symbiont Guides the Bioinformatic Discovery of Related Fungal Symbioses in Insects

Environmental Microbiology, Volume 28, Issue 7, July 2026.
Genomic, proteomic and phylogenetic analyses of the obligate yeast‐like symbiont (YLS) associated with Scaphoideus titanus revealed retained metabolic flexibility and a monophyletic origin of insect‐associated YLSs within a free‐living fungal lineage. A novel computational pipeline was used to mine NCBI transcriptomic data and identified new candidate ...
Simona Abbà, Marta Vallino, Alessandro Cicerone, Simona Cirrincione, Beatrice Aiuto, Luciana Galetto, Marika Rossi   +6 more
wiley   +1 more source

Biosynthesis of conjugated linoleic acid: current status and future perspectives. [PDF]

Bioresour Bioprocess
Lin L, Sun ML, Wang K, Gao J, Ji XJ, Zhao Q.   +5 more
europepmc   +1 more source

Glycolytic metabolism of CD8+ T‐cells affects susceptibility to human leukocyte antigen‐mediated abacavir‐induced hypersensitivity

British Journal of Pharmacology, Volume 183, Issue 13, Page 3743-3761, July 2026.
Abstract Background and Purpose Drug hypersensitivity reactions (DHRs) associated with a specific human leukocyte antigen (HLA) allotype do not manifest uniformly in all individuals within an HLA model population. This scenario highlights the complexity of predicting drug hypersensitivity reaction risk without considering additional factors ...
Takeshi Susukida, Yuchen Sun, Noriaki Arakawa, Takuya Hirao, Tadahaya Mizuno, Shigeki Aoki, Kousei Ito, Yoshihiro Hayakawa   +7 more
wiley   +1 more source

Multi-omics characterization of toxin expression and producing organs in the predatory gastropods Monoplex corrugatus and Stramonita haemastoma. [PDF]

BMC Genomics
Ringeval A, Modica MV, Kantor Y, Tenorio MJ, Galindo JCG, Puillandre N, Farhat S.   +6 more
europepmc   +1 more source

From the Proteome to Therapeutics: A Multi‐Database Approach to Drug Discovery in Periodontitis—An Exploratory Pilot Study

Journal of Clinical Periodontology, Volume 53, Issue 7, Page 990-1004, July 2026.
ABSTRACT Introduction This explanatory pilot study presents a workflow to identify approved drugs, which could be repurposed for periodontitis therapy using salivary proteomics combined with drug‐target database screening. Methods Proteomic analyses of saliva using LC–MS/MS were conducted in two independent settings: a cohort (sub‐study I, N = 187) and
Taisir Bozo, Annette Murr, Birte Holtfreter, Sebastian‐Edgar Baumeister, Peter Meisel, Uwe Völker, Werner Weitschies, Henry Völzke, Philipp Kanzow, Elke Hammer, Manuela Gesell Salazar, Thomas Kocher   +11 more
wiley   +1 more source

KRAS-elicited PDIA6 blocks PERK-dependent immunogenic cell death in pancreatic carcinoma. [PDF]

Oncoimmunology
Zhao L, Liu P, Kroemer G, Kepp O.
europepmc   +1 more source

Identification of Distinct Interacting Proteins of Giardia lamblia Centrins Using Yeast Two‐Hybrid Assays

Journal of Eukaryotic Microbiology, Volume 73, Issue 4, July/August 2026.
ABSTRACT Giardia lamblia, a protozoan parasite that causes diarrhea in humans, contains two centrins implicated in cellular morphology and cell division. To identify proteins interacting with each G. lamblia centrin (GlCent), we performed a yeast two‐hybrid assay.
Mee Young Shin, Juri Kim, Soon‐Jung Park   +2 more
wiley   +1 more source

Atypical thioredoxin Patrx2 enhances alginate production in mucoid Pseudomonasaeruginosa. [PDF]

Redox Biol
Grandjean MM, Sturgis JN, Garcin EB, Ba M, Bornet O, Bordi C, Elantak L, Sebban-Kreuzer C.   +7 more
europepmc   +1 more source