Results 221 to 230 of about 12,847 (298)

SPROUTS_DB: An Implemented Database of Contaminants for Extracellular Vesicle Proteomics Studies

open access: yesPROTEOMICS, Volume 26, Issue 7, Page 69-83, July 2026.
ABSTRACT Current proteomics techniques allow rapid identification and quantification of proteins within any given biological source. However, LC–MS/MS proteomics is vulnerable to laboratory and sample‐associated contaminants. Therefore, accurate identification and annotation of such contaminants is crucial for development of reliable databases ...
Maria Gaetana Giovanna Pittalà   +10 more
wiley   +1 more source

Branched‐Chain Amino and Keto Acids Reduce Hepatocyte Lipid Droplet Size and Number via Distinct Proteomic Pathways

open access: yesPROTEOMICS, Volume 26, Issue 7, Page 146-157, July 2026.
ABSTRACT Branched‐chain amino acids (BCAA) and their corresponding keto acids (BCKA) have been associated with changes in hepatic lipid metabolism and the resulting alterations in intracellular triglyceride concentrations. In this study, we utilized a previously established hepatocyte model to investigate the impact of BCAA and BCKA supplementation on ...
Jayasimha R. Daddam   +4 more
wiley   +1 more source

Purified zymogens reveal mechanisms of snake venom metalloproteinase auto-activation. [PDF]

open access: yesElife
Hall S   +17 more
europepmc   +1 more source

Redox signals and oxidative stress in the control of mitochondrial protein import

open access: yesProtein Science, Volume 35, Issue 7, July 2026.
Abstract Mitochondrial protein import is essential for organelle biogenesis and cellular homeostasis. It operates in an environment that is intrinsically shaped by redox chemistry. Mitochondria are major sources of reactive oxygen species (ROS), which arise as by‐products of oxidative phosphorylation. Cells therefore maintain sophisticated ROS‐handling
Lidwina Hasberg   +3 more
wiley   +1 more source

Genomic context analysis enables the discovery of an unusual NAD-dependent racemase in phosphonate catabolism. [PDF]

open access: yesFEBS J
Ruffolo F   +8 more
europepmc   +1 more source

Substrate scope of ancestral versus modern family‐1 glycosidases

open access: yesProtein Science, Volume 35, Issue 7, July 2026.
Abstract Experimental studies support that protein engineering based on ancestral sequence reconstruction often leads to variants with biotechnologically useful biomolecular properties. These may include high stability, enhanced conformational flexibility and a modified catalysis range.
Luis I. Gutierrez‐Rus   +11 more
wiley   +1 more source

Psidium Defenses Against Meloidogyne enterolobii: Proteomic and Microscopic Analysis of this Plant-Predator Association. [PDF]

open access: yesProteomics
de Oliveira Costa SN   +9 more
europepmc   +1 more source

Molecular Interplay of PARN and Telomerase: Tail Modifiers and Disease Implications

open access: yesWIREs RNA, Volume 17, Issue 4, July/August 2026.
Schematic representation of the molecular interplay between PARN, telomerase‐associated, and the involvement of p53 in regulating telomere maintenance and genome stability. The top panel shows how normal PARN levels are involved in regulating p53 levels and balanced telomerase activity through their regulatory interaction with TERC and TERRA, thus ...
Sujitha Felicitus   +5 more
wiley   +1 more source

Multifaceted Effects of Thymoquinone on Platelet Calcium Homeostasis. [PDF]

open access: yesCells
Rukoyatkina N   +4 more
europepmc   +1 more source

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