Results 41 to 50 of about 20,307 (268)
THIOL ISOMERASES – A POSSIBLE TARGET FOR THROMBOSIS CONTROL
Рациональная фармакотерапия в кардиологии, 2017 While there are an increasing number of antithrombotic agents with demonstrated clinical efficacy, thrombosis remains the leading cause of mortality in developed countries. Therefore, there is a need further development of therapies targeting alternative
I. V. Gribkova, M. V. Davydovskaya
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Heterologous Production of Fungal Maleidrides Reveals the Cryptic Cyclization Involved in their Biosynthesis [PDF]
, 2016 Fungal maleidrides are an important family of bioactive secondary metabolites that consist of 7, 8, or 9-membered carbocycles with one or two fused maleic anhydride moieties.
Bailey, Andrew M. +7 more
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Identification and Characterization of (3Z):(2E)-Hexenal Isomerases from Cucumber
Frontiers in Plant Science, 2017 E-2-hexenal is a volatile compound that is commonly emitted by wounded or stressed plants. It belongs to the group of so-called green leaf volatiles (GLVs), which play an important role in transferring information to plants and insects.
Eleni A. Spyropoulou +7 more
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Cloning, expression, purification and characterization of a DsbA-like protein from Wolbachia pipientis [PDF]
, 2008 Wolbachia pipientis are obligate endosymbionts that infect a wide range of insect and other arthropod species. They act as reproductive parasites by manipulating the host reproduction machinery to enhance their own transmission. This unusual phenotype is
Alun Jones +43 more
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Protein disulphide isomerase [PDF]
Current Biology, 2003 What is it? Protein disulphide isomerase is an enzyme with two interrelated activities: as an oxidoreductase, it can catalyse the formation, reduction and isomerisation of disulphide bonds; and as a polypeptide binding protein, it can function as a molecular chaperone which assists the folding of polypeptides.
openaire +2 more sources
Roles of Prolyl Isomerases in RNA-Mediated Gene Expression
Biomolecules, 2015 The peptidyl-prolyl cis-trans isomerases (PPIases) that include immunophilins (cyclophilins and FKBPs) and parvulins (Pin1, Par14, Par17) participate in cell signaling, transcription, pre-mRNA processing and mRNA decay.
Roopa Thapar
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The human FK506-binding proteins: characterization of human FKBP19 [PDF]
, 2006 Analysis of the human repertoire of the FK506-binding protein (FKBP) family of peptidyl-prolyl cis/trans isomerases has identified an expansion of genes that code for human FKBPs in the secretory pathway.
A Galat +43 more
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Organized condensation of worm-like chains
, 1999 We present results relevant to the equilibrium organization of DNA strands of arbitrary length interacting with a spherical organizing center, suggestive of DNA-histone complexation in nucleosomes. We obtain a rich phase diagram in which a wrapping state
H Schiessel +8 more
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FEBS Open Bio, EarlyView.ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand +2 more
wiley +1 more source
Structural Insights into the Epimerization of β-1,4-Linked Oligosaccharides Catalyzed by Cellobiose 2-Epimerase, the Sole Enzyme Epimerizing Non-anomeric Hydroxyl Groups of Unmodified Sugars [PDF]
, 2013 Cellobiose 2-epimerase (CE) reversibly converts d-glucose residues into d-mannose residues at the reducing end of unmodified β1,4-linked oligosaccharides, including β-1,4-mannobiose, cellobiose, and lactose.
Fujiwara, Takaaki +4 more
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