Results 111 to 120 of about 474 (132)
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Action of isometamidium chloride on the insect vector form of Trypanosoma vivax
Research in Veterinary Science, 1985The effect of isometamidium chloride upon developing and mature Trypanosoma vivax occurring in Glossina palpalis palpalis flies was evaluated. Newly emerged G p palpalis flies were infected with T vivax by allowing them to feed on parasitaemic animals. Two experiments were conducted and in each the flies were divided into two groups.
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Pharmacokinetics and efficacy of isometamidium chloride against Trypanosoma vivax in cattle
Parasitology InternationalWe evaluated the pharmacokinetics (pk), preventive efficacy (PE) and therapeutic efficacy (TE) of isometamidium chloride (ISM) against T. vivax. For the pk study, the animals received ISM 1 mg/kg (1 mL/40 kg) on day 0 and plasma samples were collected at day 0 (immediately before treatment), 1 h, 3 h 6 h, 9 h and 12 h after treatment, D + 1 (24 h and ...
Luiz Fellipe Monteiro, Couto +10 more
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Acta tropica, 1988
The sensitivities of 3 strains of Trypanosoma congolense to isometamidium chloride (Samorin) were determined in mice and cattle, with the objective of evaluating sensitivity testing in mice as a means of predicting curative doses in cattle. Comparison of mouse effective dose 80% (ED80) or curative dose 80% (CD80) values with cattle minimum curative ...
K R, Sones, A R, Njogu, P H, Holmes
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The sensitivities of 3 strains of Trypanosoma congolense to isometamidium chloride (Samorin) were determined in mice and cattle, with the objective of evaluating sensitivity testing in mice as a means of predicting curative doses in cattle. Comparison of mouse effective dose 80% (ED80) or curative dose 80% (CD80) values with cattle minimum curative ...
K R, Sones, A R, Njogu, P H, Holmes
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Veterinary Parasitology, 1988
Twenty dogs of mixed local East African breeds were used. Five of the dogs were uninfected controls and 15 were infected with T. brucei (ILRAD 273). Five of the infected dogs were untreated controls, five were treated with a high curative dose of diminazene aceturate, (7 mg kg-1 body weight (wt.), and five were given a subcurative dose of isometamidium
Kaggwa, E, Munyua, W K, Mugera, G M
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Twenty dogs of mixed local East African breeds were used. Five of the dogs were uninfected controls and 15 were infected with T. brucei (ILRAD 273). Five of the infected dogs were untreated controls, five were treated with a high curative dose of diminazene aceturate, (7 mg kg-1 body weight (wt.), and five were given a subcurative dose of isometamidium
Kaggwa, E, Munyua, W K, Mugera, G M
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Journal of Parasitology, 2001
Isometamidium chloride (Samorin) is therapeutic in rainbow trout (Oncorhynchus mykiss) during preclinical and chronic cryptobiosis. However, the toxic mechanism of isometamidium on Cryptobia salmositica has not been elucidated. The objective of the present study was to examine the in vitro effects of isometamidium on C. salmositica.
B F, Ardelli, P T, Woo
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Isometamidium chloride (Samorin) is therapeutic in rainbow trout (Oncorhynchus mykiss) during preclinical and chronic cryptobiosis. However, the toxic mechanism of isometamidium on Cryptobia salmositica has not been elucidated. The objective of the present study was to examine the in vitro effects of isometamidium on C. salmositica.
B F, Ardelli, P T, Woo
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Zeitschrift f�r Parasitenkunde Parasitology Research, 1984
The effect of chemoprophylaxis on developing and mature Trypanosoma vivax in Glossina tachinoides and G. palpalis palpalis was evaluated. Newly emerged G. tachinoides and G.p. palpalis flies were infected with T. vivax by allowing them to feed on parasitaemic animals.
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The effect of chemoprophylaxis on developing and mature Trypanosoma vivax in Glossina tachinoides and G. palpalis palpalis was evaluated. Newly emerged G. tachinoides and G.p. palpalis flies were infected with T. vivax by allowing them to feed on parasitaemic animals.
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Drug Metabolism and Disposition, 1996
Pharmacokinetics of the prophylactic and therapeutic trypanocidal drug isometamidium chloride were examined comprehensively for the first time in cattle using a recently described, highly sensitive ELISA. Cattle were administered single intravenous (N = 4) or intramuscular (N = 5) doses of isometamidium at a rate of 1.0 mg x kg(-1) body weight ...
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Pharmacokinetics of the prophylactic and therapeutic trypanocidal drug isometamidium chloride were examined comprehensively for the first time in cattle using a recently described, highly sensitive ELISA. Cattle were administered single intravenous (N = 4) or intramuscular (N = 5) doses of isometamidium at a rate of 1.0 mg x kg(-1) body weight ...
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Some observations on the toxicosis of isometamidium chloride (samorin) in camels.
Veterinary and human toxicology, 1986Healthy camels were experimentally infected with Trypanosoma evansi and then treated with isometamidium chloride (samorin) at single intravenous doses of 0.5 or 1.0 mg/kg. Five to 10 min after the drug administration, the camels at both dosages showed lacrimation, salivation, trembling, restlessness, frequent urination and defecation, followed by ...
B H, Ali, T, Hassan
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2023
Abstract The objective of this study was to characterize and compare the clinically visible pathological features and drug resistance patterns of two Trypanosoma isolates from two tsetse infested areas of northwest Ethiopia in experimentally infected goats.
Abrham Ayele, Shimelis Dagnachew
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Abstract The objective of this study was to characterize and compare the clinically visible pathological features and drug resistance patterns of two Trypanosoma isolates from two tsetse infested areas of northwest Ethiopia in experimentally infected goats.
Abrham Ayele, Shimelis Dagnachew
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Research in Veterinary Science, 1991
An enzyme-linked immunosorbent assay (ELISA) was developed to measure accurately levels of the trypanocidal drug isometamidium in the serum of treated cattle. The assay requires only 5 microliters of test serum, is sensitive to a level of 0.5 pg ml-1 and is highly specific.
D D, Whitelaw +6 more
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An enzyme-linked immunosorbent assay (ELISA) was developed to measure accurately levels of the trypanocidal drug isometamidium in the serum of treated cattle. The assay requires only 5 microliters of test serum, is sensitive to a level of 0.5 pg ml-1 and is highly specific.
D D, Whitelaw +6 more
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