Results 131 to 140 of about 1,075 (155)

Piloting an Information and Communication Technology Tool to Help Addressing the Challenge of Antimicrobial Resistance in Low-Income Countries. [PDF]

Antibiotics (Basel)
Mutua F, Onono JO, Boqvist S, Koech P, Abdi AM, Karimi H, Sternberg-Lewerin S.   +6 more
europepmc   +1 more source

Rational drug use: Practical training for farmers

, 2015
Grace, Delia
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Acute toxicity of samorin (Isometamidium chloride) in rabbits

Comparative Biochemistry and Physiology Part C: Comparative Pharmacology, 1984
Oral administration of samorin (isometamidium chloride) to rabbits in single oral doses of 6.25, 12.5, 25 and 50 mg/kg produced signs of toxicity which were dose-dependent. These were restlessness, hyperaesthesia, tremors, convulsions and finally death.
B H, Ali, E M, Haroun
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Preliminary pharmacokinetic study of isometamidium chloride in camels

Research in Veterinary Science, 1984
Isometamidium chloride was given to camels at a single intravenous dose rate of 0.5 or 1 mg kg-1 and the plasma drug concentration measured spectrophotometrically at frequent intervals for up to 48 hours. Isometamidium chloride concentrations were found to be 9.8 +/- 0.2 and 8.7 +/- 0.2 micrograms ml-1 half an hour after treatment with 1 and 0.5 mg kg ...
B H, Ali, T, Hassan
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Susceptibility of dyskinetoplastic Trypanosoma evansi and T. equiperdum to isometamidium chloride

Parasitology Research, 1997
Isometamidium chloride (ISM) is an effective trypanocide with curative and prophylactive activity in husbandry animals. The mode of action of ISM against pathogenic trypanosomes is not fully understood, but there is evidence in the literature that kinetoplastic topoisomerase type II is selectively inhibited by the drug.
R, Kaminsky, C, Schmid, Z R, Lun
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A comparative study of the pharmacokinetics of isometamidium chloride in sheep and goats

Small Ruminant Research, 2004
Abstract A study was carried out to determine and compare the pharmacokinetics of isometamidium in groups of six animals each of sheep and goats treated by intramuscular injection with isometamidium chloride (Samorin ® , Rhone Merieux, Lyon, France) at 0.5 mg/kg body weight.
J.O Wesongah, T.W Jones, J.K Kibugu, G.A Murilla   +3 more
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Absence of correlation between karyotype profiles of Trypanosoma congolense and resistance to isometamidium chloride

Veterinary Parasitology, 2007
Chromosome profiles of 10 Trypanosoma (T.) congolense populations with different isometamidium sensitivities were compared using the pulsed field gel electrophoresis technique. The aim was to elucidate whether there was a karyotype pattern specific to eight isometamidium resistant phenotypes.
Francis, Shahada, Peter-Henning, Clausen, Uwe, Tietjen, Takehisa, Chuma, Karoku, Okamoto   +4 more
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Action of isometamidium chloride on the insect vector form of Trypanosoma vivax

Research in Veterinary Science, 1985
The effect of isometamidium chloride upon developing and mature Trypanosoma vivax occurring in Glossina palpalis palpalis flies was evaluated. Newly emerged G p palpalis flies were infected with T vivax by allowing them to feed on parasitaemic animals. Two experiments were conducted and in each the flies were divided into two groups.
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Does isometamidium chloride treatment protect tsetse flies from trypanosome infections during SIT campaigns? [PDF]

Medical and Veterinary Entomology, 2008
Abstract African animal trypanosomosis is a major pathological constraint to cattle breeding across 10 million km 2 of sub‐Saharan West African countries infested by tsetse flies, their cyclic vectors.
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