Results 31 to 40 of about 1,075 (155)

Immunological and Therapeutic Strategies against Salmonid Cryptobiosis

BioMed Research International, Volume 2010, Issue 1, 2010., 2010
Salmonid cryptobiosis is caused by the haemoflagellate, Cryptobia salmositica. Clinical signs of the disease in salmon (Oncorhynchus spp.) include exophthalmia, general oedema, abdominal distension with ascites, anaemia, and anorexia. The disease‐causing factor is a metalloprotease and the monoclonal antibody (mAb‐001) against it is therapeutic.
Patrick T. K. Woo, Luis I. Terrazas
wiley   +1 more source

Spatiotemporal changes in prevalence of Sodalis glossinidius, Spiroplasma spp. and trypanosome species in wild Glossina tachinoides from Sora‐Mboum animal African trypanosomiasis focus in northern Cameroon

Insect Science, Volume 32, Issue 5, Page 1713-1725, October 2025.
Abstract Sterile Insect Technique (SIT) has proven effective to reduce tsetse population density in large infected areas where animal African trypanosomosis (AAT) and human African trypanosomiasis (HAT) elimination was difficult to achieve. However, the decrease in mass production of insectary‐reared tsetse and the limited but incomplete knowledge on ...
Steve Feudjio Soffack, Tito T. Melachio Tanekou, Hugues C. Nana Djeunga, Oumarou Farikou, Ginette I. Kame Ngasse, Mureille C. Tchami Mbagnia, Murielle Wondji, Charles S. Wondji, Hager Khalil, Adly M. M. Abd‐Alla, Anne Geiger, Gustave Simo, Flobert Njiokou   +12 more
wiley   +1 more source

Immunobiology of African Trypanosomes: Need of Alternative Interventions

BioMed Research International, Volume 2010, Issue 1, 2010., 2010
Trypanosomiasis is one of the major parasitic diseases for which control is still far from reality. The vaccination approaches by using dominant surface proteins have not been successful, mainly due to antigenic variation of the parasite surface coat.
Toya Nath Baral, Jorge Morales-Montor
wiley   +1 more source

Quimioterapia das Tripanosomoses ocorrentes no Pantanal. [PDF]

, 2011
bitstream/CPAP/56590/1/DOC65.pdfFormato ...
LIMA, E. S. de S., RAMIREZ, L., SILVA, R. A. M. S.   +2 more
core   +1 more source

The susceptibility of Trypanosoma congolense and Trypanosoma brucei to isometamidium chloride and its synthetic impurities

Veterinary Parasitology, 2014
Since the 1950s, the chemotherapy of animal African trypanosomosis in cattle has essentially relied on only two compounds: isometamidium chloride (ISM), a phenanthridine, and diminazene aceturate, an aromatic diamidine. The commercial formulations of ISM, including Veridium(®) and Samorin(®), are a mixture of different compounds: ISM is the major ...
Sahin, Annelise, Asencio, Corinne, Izotte, Julien, Pillay, Davita, Coustou, Virginie, Karembe, Hamadi, Baltz, Théo   +6 more
openaire   +2 more sources

Investigation of Novel Isatinylhydantoin Derivatives as Potential Anti‐Kinetoplastid Agents

ChemMedChem, Volume 20, Issue 1, January 2, 2025.
A series of isatinylhydantoin derivatives were synthesized and investigated for antileishmanial and antitrypanosomal activities in vitro and in vivo. The derivative 5 was identified with higher leishmanicidal activity than the clinical drug amphotericin B while 4b was uncovered as in vitro trypanocidal hit against T. congolense parasite.
Keamogetswe Sechoaro, Janine Aucamp, Christina Kannigadu, Helena D. Janse van Rensburg, Keisuke Suganuma, David D. N'Da   +5 more
wiley   +1 more source

Tractable Quinolone Hydrazides Exhibiting Sub‐Micromolar and Broad Spectrum Antitrypanosomal Activities

ChemMedChem, Volume 19, Issue 9, May 2, 2024.
Several (sub)species of Trypanosoma are responsible for human African trypanosomiasis (HAT), Chagas disease, and Nagana. These (sub)species have different drug susceptibility profiles. This work reports several easily accessed quinolone hydrazides exhibiting sub‐micromolar activities against multiple (sub)species of Trypanosoma.
Kgothatso A. Chirwa, Karol R. Francisco, Phelelisiwe S. Dube, Hayoung Park, Lesetja J. Legoabe, Thaiz Rodrigues Teixeira, Conor R. Caffrey, Richard M. Beteck   +7 more
wiley   +1 more source

Productivity of Boran cattle maintained by chemoprophylaxis under trypanosomiasis risk [PDF]

, 2011
Evaluates the productivity of grade Boran cattle maintained by chemoprophylaxis under severe trypanosomiasis risk at Mkwaja ranch, Tanzania; uses data based on more than 20,000 calving records over the 10-year period from 1973 to 1982; discusses ...
Durkin, J.W., Jibbo, J.M.C., Light, D.E., Murray, M., Sones, Keith R., Trail, J.C.M.   +5 more
core  

Action trypanocide du chlorhydrate de chlorure d'Isométamidium (+) sur Trypanosoma evansi et essai de traitement de la trypanosomiase du dromadaire [PDF]

, 1977
Le chlorhydrate de chlorure d'Isométamidium est doué de peu d'activité à l'égard de Trypanosoma evansi. En l'absence de produits plus actifs, son utilisation chez le dromadaire par injection intraveineuse ou intramusculaire à des doses comprises entre 0 ...
Balis, J., Richard, Didier
core  

Subverting lysosomal function in Trypanosoma brucei. [PDF]

, 2015
In this issue of Microbial Cell, Koh and colleagues present data highlighting the utility of the lysosomotropic compound L-leucyl-L-leucyl methyl ester (LeuLeu-OMe) as an anti-Trypanosoma brucei agent, adding to the range of compounds that either ...
Alsford, Sam
core   +3 more sources