Results 51 to 60 of about 334,766 (162)

The therapeutic use of isometamidium chloride against Cryptobia salmositica in rainbow trout Oncorhynchus mykiss [PDF]

Diseases of Aquatic Organisms, 1999
Rainbow trout Oncorhynchus mykiss injected intramuscularly with isometamidium chloride (0.01 or 0.1 mg kg-1) at 3 wk post-infection and given a booster 2 wk later had significantly lower parasitaemias than infected controls. Packed cell volume increased after treatment and remained higher than in infected controls. The concentration of isometamidium in
B F, Ardelli, P T, Woo
openaire   +2 more sources

Isothermal microcalorimetry – A quantitative method to monitor Trypanosoma congolense growth and growth inhibition by trypanocidal drugs in real time

International Journal for Parasitology: Drugs and Drug Resistance, 2018
Trypanosoma congolense is a protozoan parasite that is transmitted by tsetse flies, causing African Animal Trypanosomiasis, also known as Nagana, in sub-Saharan Africa. Nagana is a fatal disease of livestock that causes severe economic losses.
M. Gysin, O. Braissant, K. Gillingwater, R. Brun, P. Mäser, T. Wenzler   +5 more
doaj   +1 more source

Aberrant use and poor quality of trypanocides: a risk for drug resistance in south western Ethiopia

BMC Veterinary Research, 2018
Background Trypanocidal drugs have been used to control African animal trypanosomosis for several decades. In Ethiopia, these drugs are available from both authorized (legal) and unauthorized (illegal) sources but documentation on utilization practices ...
T. Tekle, G. Terefe, T. Cherenet, H. Ashenafi, K. G. Akoda, A. Teko-Agbo, J. Van Den Abbeele, G. Gari, P.-H. Clausen, A. Hoppenheit, R. C. Mattioli, R. Peter, T. Marcotty, G. Cecchi, V. Delespaux   +14 more
doaj   +1 more source

Kinetic modelling of isometamidium chloride (Samorin) uptake byTrypanosoma congolense

Parasitology, 1992
Clones ofTrypanosoma congolensewhich express resistance to the widely used trypanocide isometamidium chloride accumulate less of the drug than clones which are sensitive to drug treatment. A mathematical model has been developed which was able to predict theoretical lines representing the uptake kinetics in trypanosomes which were sensitive to ...
Sutherland, IA, Mounsey, A, Eisler, MC, Holmes, PH   +3 more
openaire   +3 more sources

The susceptibility of Trypanosoma congolense and Trypanosoma brucei to isometamidium chloride and its synthetic impurities

Veterinary Parasitology, 2014
Since the 1950s, the chemotherapy of animal African trypanosomosis in cattle has essentially relied on only two compounds: isometamidium chloride (ISM), a phenanthridine, and diminazene aceturate, an aromatic diamidine. The commercial formulations of ISM, including Veridium(®) and Samorin(®), are a mixture of different compounds: ISM is the major ...
Sahin, Annelise, Asencio, Corinne, Izotte, Julien, Pillay, Davita, Coustou, Virginie, Karembe, Hamadi, Baltz, Théo   +6 more
openaire   +2 more sources

PENGARUH ISOMETAMIDIUM CHLORIDE DAN KOMBINASI ISOMETAMIDIUM CHLORIDE DENGAN SURAMIN TERHADAP PACKED CELL VOLUME (PCV), PARASITEMIA, SERTA KEMATIAN TIKUS PUTIH (Rattus norvegicus) YANG DIINFEKSI T. EVANSI ISOLAT BANYUWANGI [PDF]

, 1995
Penelitian ini bertujuan untuk mengetahui pengaruh Isometamidium Chloride dan kombinasi Isometamidium Cholride dengan Suramin terhadap Packed cell volume (PCV), parasitemia, dan kematian tikus putih yang diinfeksi dengan T.
UNTARI ULFAH, 068811442
core   +1 more source

Monitoring the incidence of trypanosomosis in cattle during the release of sterilized tsetse flies on Unguja Island, Zanzibar

Revue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 2000
The incidence of trypanosomosis in sentinel cattle on Unguja Island, Zanzibar, was monitored every two to five months in 1994-97 to observe changes in disease transmission attributable logically to the application of insecticides, the release of ...
V. A. Dyck, H. Pan, S. S. Kassim, F. W. Suleiman, W. A. Mussa, K. M. Saleh, K. G. Juma, P. A. Mkonyi, W. G. Holland, B. J.M. Van Der Eerden, R. H. Dwinger   +10 more
doaj   +1 more source

Systematic Review and Meta-Analysis on Knowledge Attitude and Practices on African Animal Trypanocide Resistance

Tropical Medicine and Infectious Disease, 2022
Background: African trypanocide resistance is an emerging public health emergency whose control requires a revisit on farmer’s knowledge, attitudes, and practices in developing countries.
Keneth Iceland Kasozi, Ewan Thomas MacLeod, Charles Waiswa, Michael Mahero, Ibrahim Ntulume, Susan Christina Welburn   +5 more
doaj   +1 more source

Characterization and phylogenetic analysis of multidrug-resistant protein-encoding genes in Trypanosoma evansi isolated from buffaloes in Ngawi district, Indonesia [PDF]

Veterinary World, 2019
Background and Aim: Excessive use of trypanocidal drugs can lead to cases of drug resistance. Multiple cases of resistance have been widely reported for drugs such as isometamidium chloride and diminazene aceturate. These cases deserve serious attention,
Mohammad Mirza Nuryady, Rini Widayanti, Raden Wisnu Nurcahyo, Brilyantika Fadjrinatha, Ahmad Fahrurrozi Z. S.   +4 more
doaj   +1 more source

Evaluation of trypanocidal and anthelmintic efficacy of an Isometamidium – Ivermectin association in bovine

Revista Científica, 2021
The objective of the present work was to evaluate the efficacy of the compound Hemoveex® (isometamidium chloride  2,4% and ivermectin 2,0%) of  Reveex,  a  Venezuelan  laboratory, on the control of mixed infections of Trypanosoma vivax and ...
Gustavo López-Valencia, Jesús Antonio Betancourt-Echeverry, Elias Ascanio-Evanoff, Willia Berrío-Cataño, Andrés Felipe Velásquez-Arboleda, Jorge Gómez-Oquendo, Gustavo Alonso López-Sierra   +6 more
doaj