Results 61 to 70 of about 474 (132)

An antigen-capture enzyme-linked immunosorbent assay (ELISA) to detect isometamidium chloride in Oncorhynchus spp. [PDF]

Diseases of Aquatic Organisms, 2000
An antigen-capture enzyme-linked immunosorbent assay (ELISA) was developed to detect and measure isometamidium chloride in the plasma of Oncorhynchus tshawytscha and O. mykiss. Isometamidium-ovalbumin conjugate and anti-isometamidium antibodies were used to coat polystyrene plates.
B F, Ardelli, P T, Woo
openaire   +2 more sources

Assessment of listing and categorisation of animal diseases within the framework of the Animal Health Law (Regulation (EU) No 2016/429): Trypanosoma evansi infections (including Surra)

EFSA Journal, Volume 15, Issue 7, July 2017., 2017
Abstract Trypanosoma evansi infections (including Surra) have been assessed according to the criteria of the Animal Health Law (AHL), in particular criteria of Article 7 on disease profile and impacts, Article 5 on the eligibility of T. evansi infections (including Surra) to be listed, Article 9 for the categorisation of T. evansi infections (including
EFSA Panel on Animal Health and Welfare (AHAW), Simon More, Anette Bøtner, Andrew Butterworth, Paolo Calistri, Klaus Depner, Sandra Edwards, Bruno Garin‐Bastuji, Margaret Good, Christian Gortázar Schmidt, Virginie Michel, Miguel Angel Miranda, Søren Saxmose Nielsen, Mohan Raj, Liisa Sihvonen, Hans Spoolder, Jan Arend Stegeman, Hans‐Hermann Thulke, Antonio Velarde, Preben Willeberg, Christoph Winckler, Francesca Baldinelli, Alessandro Broglia, Denise Candiani, Beatriz Beltrán Beck, Lisa Kohnle, Joana Morgado, Dominique Bicout   +27 more
wiley   +1 more source

Comparison of the Therapeutic Efficacy of Diminazene Aceturate and ‎Isometamidium Chloride in Local Dogs Experimentally Infected ‎with Trypanosoma brucei

Sahel Journal of Veterinary Sciences, 2023
The chemotherapeutic efficacy of diminazene aceturate (DA) and isometamidium chloride (IMC) were compared in dogs experimentally infected with Trypanosoma brucei. Twenty Nigerian local breeds of dogs were used for the study. They were divided into four groups of five dogs each.
Akpa, P. O., Ukwueze, C. S., Nnaji, T. O., Anene, B. M.   +3 more
openaire   +2 more sources

Spatiotemporal changes in prevalence of Sodalis glossinidius, Spiroplasma spp. and trypanosome species in wild Glossina tachinoides from Sora‐Mboum animal African trypanosomiasis focus in northern Cameroon

Insect Science, Volume 32, Issue 5, Page 1713-1725, October 2025.
Abstract Sterile Insect Technique (SIT) has proven effective to reduce tsetse population density in large infected areas where animal African trypanosomosis (AAT) and human African trypanosomiasis (HAT) elimination was difficult to achieve. However, the decrease in mass production of insectary‐reared tsetse and the limited but incomplete knowledge on ...
Steve Feudjio Soffack, Tito T. Melachio Tanekou, Hugues C. Nana Djeunga, Oumarou Farikou, Ginette I. Kame Ngasse, Mureille C. Tchami Mbagnia, Murielle Wondji, Charles S. Wondji, Hager Khalil, Adly M. M. Abd‐Alla, Anne Geiger, Gustave Simo, Flobert Njiokou   +12 more
wiley   +1 more source

Investigation of Novel Isatinylhydantoin Derivatives as Potential Anti‐Kinetoplastid Agents

ChemMedChem, Volume 20, Issue 1, January 2, 2025.
A series of isatinylhydantoin derivatives were synthesized and investigated for antileishmanial and antitrypanosomal activities in vitro and in vivo. The derivative 5 was identified with higher leishmanicidal activity than the clinical drug amphotericin B while 4b was uncovered as in vitro trypanocidal hit against T. congolense parasite.
Keamogetswe Sechoaro, Janine Aucamp, Christina Kannigadu, Helena D. Janse van Rensburg, Keisuke Suganuma, David D. N'Da   +5 more
wiley   +1 more source

Tractable Quinolone Hydrazides Exhibiting Sub‐Micromolar and Broad Spectrum Antitrypanosomal Activities

ChemMedChem, Volume 19, Issue 9, May 2, 2024.
Several (sub)species of Trypanosoma are responsible for human African trypanosomiasis (HAT), Chagas disease, and Nagana. These (sub)species have different drug susceptibility profiles. This work reports several easily accessed quinolone hydrazides exhibiting sub‐micromolar activities against multiple (sub)species of Trypanosoma.
Kgothatso A. Chirwa, Karol R. Francisco, Phelelisiwe S. Dube, Hayoung Park, Lesetja J. Legoabe, Thaiz Rodrigues Teixeira, Conor R. Caffrey, Richard M. Beteck   +7 more
wiley   +1 more source

The response of pigs experimentally infected with trypanosoma brucei to isometamidium chloride therapy and the relation to nutrition

Veterinary Quarterly, 1992
Growing pigs were placed on feeds with high (Group A), medium (B) and low (C) dietary energy and were infected with a virulent stock of T. brucei. Eight weeks later, the infected pigs were treated with isometamidium chloride at 1 mg/kg live weight and all pigs were subsequently placed on a high energy diet to investigate their response to therapy ...
E B, Otesile, B O, Fagbemi, M O, Makinde, O A, Akinboade   +3 more
openaire   +2 more sources

Study of mRNA expression of thirteen genes of Trypanosoma evansi in response to diminazene aceturate and isometamidium chloride

Indian Journal of Animal Sciences
The monomorphic, non-cyclic, extracellular haemoprotozoan parasite, Trypanosoma evansi leads to Surra disease in domesticated animals. Currently, diminazene aceturate (DA) and isometamidium chloride (ISM) are the most used chemotherapeutic agents for ...
SNEHIL GUPTA, SUKHDEEP VOHRA, KHUSHBOO SETHI, RUMA RANI, SURBHI GUPTA, RAJENDER KUMAR, SANJAY KUMAR   +6 more
doaj   +1 more source

A cross-sectional study on the use and misuse of trypanocides in selected pastoral and agropastoral areas of eastern and northeastern Tanzania

Parasites & Vectors, 2017
Background Tsetse-borne African animal trypanosomosis (AAT) greatly influences livestock distribution and significantly slows livestock productivity in sub-Saharan Africa.
Anna F. Ngumbi, Richard S. Silayo
doaj   +1 more source

Detection of multiple drug-resistant Trypanosoma congolense populations in village cattle of south-east Mali

Parasites & Vectors, 2012
Background Tsetse fly-transmitted African animal trypanosomosis causes annual losses that run into billions of dollars. The disease is assumed to cause hunger and poverty in most sub-Saharan countries since it represents a serious impediment to ...
Mungube Erick O, Vitouley Hervé S, Allegye-Cudjoe Emmanuel, Diall Oumar, Boucoum Zakaria, Diarra Boucader, Sanogo Yousouf, Randolph Thomas, Bauer Burkhard, Zessin Karl-Hans, Clausen Peter-Henning   +10 more
doaj   +1 more source