Results 71 to 80 of about 474 (132)

Isometamidium chloride prophylaxis against Trypanosoma congolense challenge and the development of immune responses in Boran cattle

open access: yesVeterinary Record, 1986
Twenty-four Boran cattle were injected with isometamidium chloride (1 mg/kg bodyweight) to investigate the duration of drug-induced prophylaxis against infection by metacyclic forms of Trypanosoma congolense and to determine if specific antibody responses to the organism were mounted by animals under chemoprophylactic cover. Complete protection against
Whitelaw, D.D.   +6 more
openaire   +2 more sources

Prevalence of bovine trypanosomosis and assessment of trypanocidal drug resistance in tsetse infested and non-tsetse infested areas of Northwest Ethiopia

open access: yesParasite Epidemiology and Control, 2017
The Northwestern region of Ethiopia is affected by both tsetse and non-tsetse transmitted trypanosomosis with a significant impact on livestock productivity. The control of trypanosomosis in Ethiopia relies on either curative or prophylactic treatment of
Shimelis Dagnachew   +9 more
doaj   +1 more source

Clinical and therapeutic aspects of an outbreak of canine trypanosomiasis

open access: yesRevista Brasileira de Parasitologia Veterinária
Trypanosomiasis caused by Trypanosoma evansi can seriously affect both domestic and wild animals. This article reports on an outbreak of canine trypanosomiasis on a farm in the Pantanal region of Brazil.
Jessica Teles Echeverria   +9 more
doaj   +1 more source

Differences in sensitivity of KenyanTrypanosoma vivax populations to the prophylactic and therapeutic actions of isometamidium chloride in Boran cattle

open access: yesTropical Animal Health and Production, 1991
Isometamidium chloride was administered as a single prophylactic dose of 0.5 mg kg-1 body weight to each of 10 Boran (Bos indicus) steers. At monthly intervals following drug administration, groups of five cattle each were challenged with one of two different Trypanosoma vivax populations transmitted by infected Glossina morsitans centralis; one with a
Peregrine, A.S.   +2 more
openaire   +3 more sources

New Trypanosoma evansi Type B Isolates from Ethiopian Dromedary Camels.

open access: yesPLoS Neglected Tropical Diseases, 2016
BackgroundTrypanosoma (T.) evansi is a dyskinetoplastic variant of T. brucei that has gained the ability to be transmitted by all sorts of biting flies. T.
Hadush Birhanu   +4 more
doaj   +1 more source

Variation in resistance to isometamidium chloride and diminazene aceturate by clones derived from a stock ofTrypanosoma congolense

open access: yesParasitology, 1991
SUMMARYNine clones were derived from a drug-resistantTrypanosoma congolensestock (IL 2856) and characterized in mice for their sensitivity to isometamidium chloride and diminazene aceturate. All clones were derived from the stock without drug selection and expressed high levels of resistance to isometamidium chloride (50% curative dose [CD50] values ...
Peregrine, A.S.   +5 more
openaire   +3 more sources

Therapeutic efficacy of isometamidium chloride in the treatment of Trypanosoma congolense infection in Sokoto Red bucks

open access: yesSavannah Veterinary Journal, 2020
Introduction: Treatment of animal trypanosomiasis using isometamidium chloride (ISM) is largely done with 1% solution however, 2% solution has been found to be more effective. In this study, therapeutic efficacy of ISM drug concentrations was studied in Trypanosoma congolense infected Sokoto Red Bucks (SRB).
openaire   +1 more source

Effect of dose on disposition kinetics of isometamidium chloride/hydrochloride in trypanosomiasis induced calves

open access: yesAfrican Journal of Pharmacy and Pharmacology, 2013
Effect of dose on disposition kinetics of isometamidium (ISMM) in Indian buffalo calves was studied in view of limited applications of the drug in India. Buffalo calves were pre grouped and trypanosomiasis was induced using Trypanosoma evansi. ISMM was administered intravenously at 0.25, 0.5 and 1 mg/kg (body weight) to the grouped animals.
openaire   +2 more sources

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