Engineering of Transmembrane Alkane Monooxygenases to Improve a Key Reaction Step in the Synthesis of Polymer Precursor Tulipalin A [PDF]
Angew Chem Int Ed EnglA biosynthesis route for the polymer precursor tulipalin A starting from isoprenyl acetate is proposed. The alkane monooxygenase AlkB catalyzes the chemoselective terminal hydroxylation of isoprenyl acetate. Rational enzyme engineering further increased the activity of the membrane enzyme.
Nigl A +10 more
europepmc +3 more sources
Targeting the isoprenoid pathway in choleste biosynthesis: An approach to identify isoprenoid biosynthesis inhibitors. [PDF]
Arch Pharm (Weinheim)A fully validated assay is reported that can be used to identify inhibitors of isoprenoid biosynthesis by gas chromatography‐mass spectrometry (GC‐MS). The free isoprenoids can be distinguished from their pyrophosphorylated species. From 11 literature‐described isoprenoid biosynthesis inhibitors, eight influenced the isoprenoid patterns of HL60 cells ...
Liebl M, Olander F, Müller C.
europepmc +2 more sources
Determination of Three Glycosides in Tobacco Using Heart Cutting Rp/Rp Two Dimensional Liquid Chromatography Tandem Mass Spectrometry [PDF]
Zhipu Xuebao, 2021 A method for glycosides detection in tobacco leaves by heart cutting Rp/Rp two dimensional liquid chromatography tandem mass spectrometry was established.
CHEN Min +6 more
doaj +1 more source
Isoprenol‐Induced Neuroprotection in Experimental Multiple Sclerosis
The FASEB Journal, 2018 Study Objectives Farnesol is a 15‐carbon organic acyclic sesquiterpene alcohol (isoprenol) produced by plants and animals. It is a potent blocker of neuronal voltage‐gated Ca 2+ channels (L‐ and N‐type) and it is found in the human brain (Roullet,
Kevin D. Strawn +6 more
openaire +2 more sources
Experimental Data: Distillation Behavior of the System (Formaldehyde + Water + Isoprenol)
, 2022 Excel file containing the experimental data corresponding to the publication: M. Dyga, A. Keller, H. Hasse: Distillation Behavior of the System (Formaldehyde + Water + Isoprenol), DOI: 10.1016/j.ces.2022 ...
Dyga, M
core +2 more sources
Variation of Clasper Scent Gland Composition of Heliconius Butterflies from a Biodiversity Hotspot
ChemBioChem, Volume 24, Issue 22, November 16, 2023., 2023 Male Heliconius butterflies, which occur locally in three mimicry groups, show an extremely high diversity of compounds in their clasper scent glands. The more than 1,000 different compounds identified in 17 species are used for species‐specific mixtures of volatile and non‐volatile compounds, presumably used for chemical communication.
Stephanie Ehlers +4 more
wiley +1 more source
Cysteine‐Selective Modification of Peptides and Proteins via Desulfurative C−C Bond Formation
Chemistry – A European Journal, Volume 29, Issue 16, March 16, 2023., 2023 A cysteine‐selective, visible‐light‐mediated bioconjugation reaction that enables direct installation of a range of desired moieties into peptide and protein scaffolds via C(sp3)−C(sp3) bond formation is described. The method is rapid, operationally simple, tolerant to ambient atmosphere and can be utilized to incorporate general tools for chemical ...
Rhys C. Griffiths +11 more
wiley +1 more source
Biosynthesis of geranate via isopentenol utilization pathway in Escherichia coli
Biotechnology and Bioengineering, Volume 120, Issue 1, Page 230-238, January 2023., 2023 Abstract Isoprenoids are a large family of natural products with diverse structures, which allow them to play diverse and important roles in the physiology of plants and animals. They also have important commercial uses as pharmaceuticals, flavoring agents, fragrances, and nutritional supplements.
Qiuchi Pan +6 more
wiley +1 more source
, 2021 Isoprenol (3-methyl-3-buten-1-ol) is an important intermediate in the chemical industry, which is used, for example, in the production of citral. It is produced from aqueous formaldehyde and isobutene and has to be separated from mixtures containing ...
Andreas Keller (29147) +2 more
core +1 more source
Odor Characteristics of Novel Non-Canonical Terpenes
Molecules, 2022 Several non-canonical, methylated terpenes have been described as products of genetically modified Escherichia coli recently, and the aroma properties of 28 odor-active methylated derivatives of prenol, isoprenol, bornane, camphene, carene, citronellol ...
Svenja Sommer +5 more
doaj +1 more source