Separation of Isoprenol‐Dimethyldioxane Mixture by Vacuum and Extractive Distillation
International Journal of Chemical EngineeringThis study investigates the isolation of commercial isoprenol, a by-product of large-scale isoprene production. The challenge lies in separating isoprenol from an azeotropic mixture with 4,4-dimethyldioxane-1,3.
Alexander V Klinov +2 more
exaly +4 more sources
Evolutionary engineering of E. coli MG1655 for tolerance against isoprenol [PDF]
Biotechnology for Biofuels, 2020 Background Isoprenol is the basis for industrial flavor and vitamin synthesis and also a promising biofuel. Biotechnological production of isoprenol with E. coli is currently limited by the high toxicity of the final product.
Heiko Babel, Jens O Krömer
exaly +5 more sources
Targeting the isoprenoid pathway in choleste biosynthesis: An approach to identify isoprenoid biosynthesis inhibitors. [PDF]
Arch Pharm (Weinheim)The development of novel cholesterol biosynthesis inhibitors is a task of major concern due to the diverse roles of cholesterol and its precursors in physiological processes.
Liebl M, Olander F, Müller C.
europepmc +4 more sources
Evolution-guided tolerance engineering of Pseudomonas putida KT2440 for production of the aviation fuel precursor isoprenol [PDF]
Metabolic EngineeringIsoprenol (3-methyl-3-buten-1-ol) is a precursor to aviation fuels and other commodity chemicals and can be microbially synthesized from renewable carbon streams.
Hyun Gyu Lim +2 more
exaly +5 more sources
Multi-layered metabolic remodeling of Pseudomonas putida for efficient conversion of lignocellulosic sugars to the precursors of advanced aviation fuel [PDF]
Metabolic Engineering CommunicationsIsoprenyl acetate, a volatile ester derived from isoprenol, is a key biosynthetic intermediate for the advanced aviation fuel candidate, 1,4-dimethylcyclooctane.
Chae Won Kang +7 more
doaj +2 more sources
Quantifying Isoprenoids in the Ergosterol Biosynthesis by Gas Chromatography–Mass Spectrometry [PDF]
Journal of Fungi, 2023 The ergosterol pathway is a promising target for the development of new antifungals since its enzymes are essential for fungal cell growth. Appropriate screening assays are therefore needed that allow the identification of potential inhibitors.
Maximilian Liebl +6 more
doaj +2 more sources
Activity of bacteria isolated from bats against Pseudogymnoascus destructans in China
Microbial Biotechnology, 2022 Summary White‐nose syndrome, a disease that is caused by the psychrophilic fungus Pseudogymnoascus destructans, has threatened several North America bat species with extinction.
Zhongle Li +10 more
doaj +2 more sources
Metabolic Engineering of the Isopentenol Utilization Pathway Enhanced the Production of Terpenoids in Chlamydomonas reinhardtii [PDF]
Marine Drugs, 2022 Eukaryotic green microalgae show considerable promise for the sustainable light-driven biosynthesis of high-value fine chemicals, especially terpenoids because of their fast and inexpensive phototrophic growth.
Mei-Li Zhao +7 more
doaj +2 more sources
Fast growth and high-titer bioproduction from renewable formate via metal-dependent formate dehydrogenase in Escherichia coli [PDF]
Nature CommunicationsMicrobial bioproduction using one-carbon (C1) feedstocks has the potential to decarbonize the manufacturing of materials, fuels, and chemicals. Formate is a promising C1 feedstock, and the realization of industrial, formatotrophic platform organisms is a
Aidan E. Cowan +20 more
doaj +2 more sources
Enhancement of linalool production in Saccharomyces cerevisiae by utilizing isopentenol utilization pathway [PDF]
Microbial Cell Factories, 2022 Background Linalool is a monoterpenoid, also a vital silvichemical with commercial applications in cosmetics, flavoring ingredients, and medicines. Regulation of mevalonate (MVA) pathway metabolic flux is a common strategy to engineer Saccharomyces ...
Yaoyao Zhang +3 more
doaj +2 more sources