Microbial production of high octane and high sensitivity olefinic ester biofuels [PDF]
Background Advanced spark ignition engines require high performance fuels with improved resistance to autoignition. Biologically derived olefinic alcohols have arisen as promising blendstock candidates due to favorable octane numbers and synergistic ...
David N. Carruthers +8 more
doaj +2 more sources
Optimizing Archaeal Lipid Biosynthesis in <i>Escherichia coli</i>. [PDF]
Membrane lipid chemistry is remarkably different in archaea compared with bacteria and eukaryotes. In the evolutionary context, this is also termed the lipid divide and is reflected by distinct biosynthetic pathways.
Hoekzema M, Jiang J, Driessen AJM.
europepmc +4 more sources
Enhanced isoprenoid production in Escherichia coli cells harboring the archaeal mevalonate pathway [PDF]
Microbial production of isoprenoids has attracted interest as a white biotechnology approach that yields valuable compounds, such as medicinal, biofuel, and sustainable industrial materials.
Takuya Takahashi +4 more
doaj +2 more sources
FluxRETAP: a REaction TArget Prioritization genome-scale modeling technique for selecting genetic targets. [PDF]
MOTIVATION: Metabolic engineering is rapidly evolving as a result of new advances in synthetic biology tools and automation platforms that enable high throughput strain construction, as well as the development of machine learning tools (ML) for biology ...
Czajka JJ +5 more
europepmc +3 more sources
Micro and mesoporous materials based on zeolite Y for the florol synthesis via the prins cyclization of isoprenol [PDF]
Several parents and Sn-modified microporous and mesoporous catalysts were investigated in Prins cyclization of isoprenol with isovaleraldehyde for the production of the desired cis isomer of pyranol, Florol ® using dimethylcarbonate as a solvent in the ...
Angervo Ilari +9 more
core +2 more sources
Engineering of Transmembrane Alkane Monooxygenases to Improve a Key Reaction Step in the Synthesis of Polymer Precursor Tulipalin A [PDF]
A biosynthesis route for the polymer precursor tulipalin A starting from isoprenyl acetate is proposed. The alkane monooxygenase AlkB catalyzes the chemoselective terminal hydroxylation of isoprenyl acetate. Rational enzyme engineering further increased the activity of the membrane enzyme.
Nigl A +10 more
europepmc +3 more sources
Cysteine-Selective Modification of Peptides and Proteins via Desulfurative C-C Bond Formation. [PDF]
A cysteine‐selective, visible‐light‐mediated bioconjugation reaction that enables direct installation of a range of desired moieties into peptide and protein scaffolds via C(sp3)−C(sp3) bond formation is described. The method is rapid, operationally simple, tolerant to ambient atmosphere and can be utilized to incorporate general tools for chemical ...
Griffiths RC +11 more
europepmc +2 more sources
Determination of Three Glycosides in Tobacco Using Heart Cutting Rp/Rp Two Dimensional Liquid Chromatography Tandem Mass Spectrometry [PDF]
A method for glycosides detection in tobacco leaves by heart cutting Rp/Rp two dimensional liquid chromatography tandem mass spectrometry was established.
CHEN Min +6 more
doaj +1 more source
Biosynthesis of geranate via isopentenol utilization pathway in Escherichia coli. [PDF]
Abstract Isoprenoids are a large family of natural products with diverse structures, which allow them to play diverse and important roles in the physiology of plants and animals. They also have important commercial uses as pharmaceuticals, flavoring agents, fragrances, and nutritional supplements.
Pan Q +6 more
europepmc +2 more sources
Multiomics Data Collection, Visualization, and Utilization for Guiding Metabolic Engineering
Biology has changed radically in the past two decades, growing from a purely descriptive science into also a design science. The availability of tools that enable the precise modification of cells, as well as the ability to collect large amounts of ...
Somtirtha Roy +28 more
doaj +1 more source

