Results 101 to 110 of about 33,489 (175)

Tabernaemontana catharinensis: A Source of Indole Alkaloids With Potential Activity as Chemotherapeutic Agents

Chemistry &Biodiversity, Volume 23, Issue 4, April 2026.
ABSTRACT This study aimed to evaluate the antitumor activity of fractions rich in indole alkaloids extracted from the leaves of the species Tabernaemontana catharinensis. The chemical composition was analyzed using high‐resolution mass spectrometry (HRMS), which identified nine known indole alkaloids, including voacangine, voacangine hydroxyindolenine,
Ana Júlia Gomes Donada, Rafael Freitas Corá, Bianca Canci, Mariana Roesch‐Ely, Pauline Fagundes Rosales, Sidnei Moura   +5 more
wiley   +1 more source

Advances in the Preparation of Fluorinated Isoquinolines: A Decade of Progress

Journal of Chemistry, 2017
Heterocyclic molecules incorporating fluorinated isoquinoline components are found in many medicinally and agriculturally important bioactive products as well as industrially impactful materials.
Joseph C. Sloop
doaj   +1 more source

1-(4-Chloro-3-fluorophenyl)-2-[(3-phenylisoquinolin-1-yl)sulfanyl]ethanone

Acta Crystallographica Section E, 2009
In the title compound, C23H15ClFNOS, the isoquinoline system and the 4-chloro-3-fluorophenyl ring are aligned at 80.4 (1)°. The dihedral angle between the isoquinoline system and the pendant (unsubstituted) phenyl ring is 19.91 (1)°.
F. Nawaz Khan, N. Burcu Arslan, T. Maiyalagan, Venkatesha R. Hathwar, P. Manivel   +4 more
doaj   +1 more source

Research Progress of Polyoxometalate‐Integrated Frameworks: Syntheses, Properties, and Applications

ChemistryEurope, Volume 4, Issue 4, April 2026.
This review systematically summarizes the integration of polyoxometalates with covalent organic frameworks, metal‐organic frameworks, hydrogen‐bonded organic frameworks, and emerging porous hosts. It highlights synergistic effects, synthesis strategies, and applications in catalysis, energy storage, sensing, and biomedicine, while addressing current ...
De‐Yin Wang, Zhang‐Di Liu, Rui Xing, Zi‐Hao Wei, Zaixiang Zhang, Yang Yang, Jin Zhu   +6 more
wiley   +1 more source

Phytochemical study on Berberis sibirica Pall.

Mongolian Journal of Chemistry, 2014
From the aerial parts (700g) of berberis sibirica pall. 6 isoquinoline alkaloids of protoberberine, protopine, benzophenantridine and proaporphine type were isolated. The known alkaloids (-)-tetrahydropseudocoptisine, pseudoprotopine, (+)-chelidonine and
A Solongo, R Istatkova, S Philipov, S Javzan, D Selenge   +4 more
doaj   +1 more source

Regioselective reactions of 3,4-pyridynes enabled by the aryne distortion model. [PDF]

, 2013
The pyridine heterocycle continues to play a vital role in the development of human medicines. More than 100 currently marketed drugs contain this privileged unit, which remains highly sought after synthetically. We report an efficient means to access di-
Garg, Neil K, Goetz, Adam E
core  

Skeletal Editing from Pyridine to Aniline via C‐Insertion and N‐Isomerization

ChemistryEurope, Volume 4, Issue 4, April 2026.
A concise protocol is presented that converts pyridines into anilines by externalizing the original pyridine nitrogen at either the "ipso" or "ortho" position, which results in para or meta‐primary aniline products. A key carbene‐insertion step precedes nitrogen migration, preserving both ring size and overall structure.
Yun Luo, Jing Dai, Yongchang Wei, Chang Min   +3 more
wiley   +1 more source

1-(4-Chlorophenyl)-2-[(3-phenylisoquinolin-1-yl)sulfanyl]ethanone

Acta Crystallographica Section E, 2009
The title compound, C23H16ClNOS, exhibits dihedral angles of 11.73 (1) and 66.07 (1)°, respectively, between the mean plane of the isoquinoline system and the attached phenyl ring, and between the isoquinoline system and the chlorophenyl
F. Nawaz Khan, R. Subashini, P. Nithya, Venkatesha R. Hathwar, P. Manivel   +4 more
doaj   +1 more source

Copper‐ and Silver‐Catalyzed Reactions of Active Methylene Isocyanides: Facile Access to Highly Substituted Five‐ and Six‐Membered Heterocycles

Chemistry – A European Journal, Volume 32, Issue 13, 1 April 2026.
This review summarizes recent advances in copper‐ and silver‐catalyzed reactions of active methylene isocyanides for the synthesis of highly substituted five‐ and six‐membered heterocycles. Emphasis is placed on [3+n] cycloadditions, annulations, and asymmetric strategies, highlighting current limitations and future opportunities in heterocycle ...
Jimil George, Kyungsoo Oh
wiley   +1 more source

An Overview on the Synthesis of Lamellarins and Related Compounds with Biological Interest

Molecules
Lamellarins are natural products with a [3,4]-fused pyrrolocoumarin skeleton possessing interesting biological properties. More than 70 members have been isolated from diverse marine organisms, such as sponges, ascidians, mollusks, and tunicates.
Vasiliki-Panagiota M. Mitsiou, Anastasia-Maria N. Antonaki, Matina D. Douka, Konstantinos E. Litinas   +3 more
doaj   +1 more source