Results 101 to 110 of about 24,191 (225)

1-[3-(4-Chlorophenyl)isoquinolin-1-yl]-3,5-diphenyl-1H-pyrazole

open access: yesActa Crystallographica Section E, 2010
The title compound, C30H20ClN3, is composed of a diaryl-substituted pyrazole ring connected to an aryl-substituted isoquinoline ring system with a dihedral angle of 65.1 (1)° between the pyrazole ring and the isoquinoline ring system ...
F. Nawaz Khan   +4 more
doaj   +1 more source

Retro‐Hetero‐Michael Addition Strategies in Organic Synthesis

open access: yesEuropean Journal of Organic Chemistry, Volume 29, Issue 32, 24 August 2026.
In this review, synthetic approaches to carbo‐ and heterocyclic compounds, including natural products, published in the last 15 years (2011–2025) which have either relied upon or included a retro‐hetero‐Michael addition step at any stage are discussed.
Dina Scarpi, Ernesto G. Occhiato
wiley   +1 more source

The effect of isoquinoline alkaloids on opiate withdrawal

open access: yes, 2006
Our interest has been centered on isoquinoline alkaloids obtained from Argemone mexicana (Papaveraceae), Aristolochia constricta (Aristolochiaceae) and the opium alkaloid, papaverine.
PIZZA, Cosimo   +4 more
core   +1 more source

From o‐Phenylenediamine to Flavin Derivatives: A Potential Prebiotic Carbon Skeleton Expansion With Formaldehyde, Cyanide, and CO2

open access: yesAdvanced Synthesis &Catalysis, Volume 368, Issue 16, 18 August 2026.
A Strecker‐type reaction of aromatic ortho‐diamines with various aldehydes and cyanide assembles the bicyclic amidine core of flavin‐derived heterocycles under mild conditions. Subsequent oxidation, radical or photochemical cyanation, carboxylation with CO2, and CO2‐mediated cyclization build the three‐ring alloxazine scaffold. This sequence provides a
Christian Held   +2 more
wiley   +1 more source

Synthesis of Trisubstituted Isoquinoline Alkaloids

open access: yes, 2019
Isoquinoline alkaloids encompasses a large and important group of naturally occurring substances that exhibit a diverse array of biological activity, including treating Yaws and worm infections,1 as well as showing activity as both topoisomerase ...
Tran, Thao   +3 more
core   +1 more source

Advances in the Preparation of Fluorinated Isoquinolines: A Decade of Progress

open access: yesJournal of Chemistry, 2017
Heterocyclic molecules incorporating fluorinated isoquinoline components are found in many medicinally and agriculturally important bioactive products as well as industrially impactful materials.
Joseph C. Sloop
doaj   +1 more source

Dichloridobis(isoquinoline-κN)zinc(II)

open access: yes, 2010
In the title compound, [ZnCl2(C9H7N)2], the ZnII cation is coordinated by two Cl− anions and two isoquinoline ligands in a distorted ZnCl2N2 tetrahedral geometry; the two isoquinoline ring systems are twisted with respect to each other at a ...
Duan-Jun Xu, Jing-Jing Nie, Meng-Jiao Li
core   +1 more source

An Overview on the Synthesis of Lamellarins and Related Compounds with Biological Interest

open access: yesMolecules
Lamellarins are natural products with a [3,4]-fused pyrrolocoumarin skeleton possessing interesting biological properties. More than 70 members have been isolated from diverse marine organisms, such as sponges, ascidians, mollusks, and tunicates.
Vasiliki-Panagiota M. Mitsiou   +3 more
doaj   +1 more source

Synthesis and structural characterization of ferrocene-isoquinoline hybrids

open access: yes, 2017
U ovom radu opisana je sinteza novih derivata izokinolina i ferocen-izokinolinskog hibrida te njihova strukturna karakterizacija. Reakcijom ciklizacije potpomognutom mikrovalnim zračenjem 2-klorbenzaldehida i odgovarajućih terminalnih alkina ...
Lojan, Petra
core   +1 more source

Catalyst- and Additive-Free Cascade Reaction of Isoquinoline N‑Oxides with Alkynones: An Approach to Benzoazepino[2,1‑a]isoquinoline Derivatives

open access: yes, 2019
A cascade reaction of isoquinoline N-oxides with alkynones was developed, delivering a fluorescent benzoazepino­[2,1-a]­isoquinoline derivative. The reaction worked smoothly without requirement of any catalyst or additive, making this method economical ...
Guanghua Zhou   +9 more
core   +1 more source

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