Results 1 to 10 of about 451 (130)

Selective construction of dispiro[indoline-3,2'-quinoline-3',3''-indoline] and dispiro[indoline-3,2'-pyrrole-3',3''-indoline] via three-component reaction

Beilstein Journal of Organic Chemistry, 2023
A convenient synthetic procedure for the construction of novel dispirooxindole motifs was successfully developed by base-promoted three-component reaction of ammonium acetate, isatins and in situ-generated 3-isatyl-1,4-dicarbonyl compounds.
Ziying Xiao, Fengshun Xu, Jing Sun, Chao-Guo Yan   +3 more
doaj   +3 more sources

Development and Application of Indolines in Pharmaceuticals

ChemistryOpen, 2023
In recent years, the incidence of cancer is high around the world, and the resistance of bacteria is increasing. To cope with the potentially adverse side effects of cancer chemotherapy and surgery, researchers are turning to the construction of new drug
Huixin Wei, Bo Li, Ning Wang, Yitian Ma, Jingyan Yu, Xuena Wang, Jiayi Su, Prof. Dr. Dan Liu   +7 more
doaj   +3 more sources

Using High Performance Liquid Chromatography to Analyse Indoline Degradation During Lead Bioremoval

Chemical Engineering Transactions, 2022
Analysis was conducted on the degradation of indoline present in LB (Luria Bertani broth) broth used as rich growth medium during the bioremoval of Pb(II) using an industrially obtained microbial consortium.
Carla Cilliers, Evans M. N. Chirwa, Hendrik G. Brink   +2 more
doaj   +1 more source

Synthesis of a Spirocyclic Indoline Lactone [PDF]

The Journal of Organic Chemistry, 2004
AbstractFor Abstract see ChemInform Abstract in Full Text.
John C, Hodges, Wei, Wang, Frank, Riley
openaire   +2 more sources

Indoline-6-Sulfonamide Inhibitors of the Bacterial Enzyme DapE

Antibiotics, 2020
Inhibitors of the bacterial enzyme dapE-encoded N-succinyl-l,l-diaminopimelic acid desuccinylase (DapE; EC 3.5.1.18) hold promise as antibiotics with a new mechanism of action. Herein we describe the discovery of a new series of indoline sulfonamide DapE
Cory T. Reidl, Tahirah K. Heath, Iman Darwish, Rachel M. Torrez, Maxwell Moore, Elliot Gild, Boguslaw P. Nocek, Anna Starus, Richard C. Holz, Daniel P. Becker   +9 more
doaj   +1 more source

Methyl 5′-Chloro-8-formyl-5-hydroxy-1′,3′,3′-trimethyl-spiro-[chromene-2,2′-indoline]-6-carboxylate

Molbank, 2023
Spiropyrans modified with reactive polyfunctional substituents are of great interest as building blocks for the creation of various smart systems with controllable properties for materials science and biomedicine.
Ilya V. Ozhogin, Artem D. Pugachev, Anastasia S. Kozlenko, Irina A. Rostovtseva, Nadezhda I. Makarova, Gennady S. Borodkin, Islam M. El-Sewify, Anatoly V. Metelitsa, Boris S. Lukyanov   +8 more
doaj   +1 more source

Synthesis, antimicrobial activity and molecular docking studies of spiroquinoline-indoline-dione and spiropyrazolo-indoline-dione derivatives

Scientific Reports, 2023
Spiro[benzo[h]quinoline-7,3′-indoline]diones and spiro[indoline-3,4′-pyrazolo[3,4-b]quinoline]diones were efficiently synthesized via one-pot multi-component reactions under ultrasound-promoted conditions.
Melek Gul, Emine Turk Celikoglu, Onder Idil, Gamze Tas, Emel Pelit   +4 more
doaj   +1 more source

Inhibitory Effect of Puroindoline Peptides on Campylobacter jejuni Growth and Biofilm Formation

Frontiers in Microbiology, 2021
Puroindolines are small, amphipathic, wheat proteins that determine the hardness of the wheat kernel and protect crops from different pathogens. Puroindoline A (PinA) and puroindoline B (PinB) are two major isoforms of puroindolines.
Prabhat K. Talukdar, Kyrah L. Turner, Torin M. Crockett, Xiaonan Lu, Craig F. Morris, Michael E. Konkel   +5 more
doaj   +1 more source

Crystal structure of (1′S,2′S,3S)-1′-benzoyl-2′-(4-methoxyphenyl)-1-methyl-2′,5′,6′,10b′-tetrahydro-1′H-spiro[indoline-3,3′-pyrrolo[2,1-a]isoquinolin]-2-one

Acta Crystallographica Section E: Crystallographic Communications, 2020
In the title spiro compound, C34H30N2O3, the central pyrrolidine ring is fused with the tetrahydroisoquinoline ring, both having distorted envelope conformations, with the flap atoms being C and N, respectively. The methoxyphenyl group is attached to the
Janet Priyavathani Selvaraj, Stella Mary, Jyoti Boruah Dhruba, Birkumar Singh Huidrom, Yuvaraj Panneerselvam, Kannan Piskala Subburaman   +5 more
doaj   +1 more source

5′,6-Dichloro-1′,3′,3′-trimethylspiro[2H-1-benzopyran-2,2′-indoline]

Acta Crystallographica Section E, 2008
In the crystal structure of the title compound, C19H17Cl2NO, the indoline and benzopyran ring systems are approximately perpendicular to each other. The indoline ring is in an envelope conformation with the spiro C atom as the flap.
Nameer Alhashimy, Helge Müller-Bunz, Benjamin Schazmann, Dermot Diamond   +3 more
doaj   +1 more source