Results 31 to 40 of about 13,350 (226)

Design, Synthesis of New 1,2,4-Triazole/1,3,4-Thiadiazole with Spiroindoline, Imidazo[4,5-b]quinoxaline and Thieno[2,3-d]pyrimidine from Isatin Derivatives as Anticancer Agents

Molecules, 2022
The current work aims to design and synthesis a new series of isatin derivatives and greatly enhances their cytotoxic activity. The derivatives 3-((bromophenyl) imino)-1-(morpholino (pyridine) methyl) indolin-2-one, 2-((oxoindoline) amino) benzoic acid ...
Ameen Ali Abu-Hashem, Sami A. Al-Hussain
doaj   +1 more source

Efficient Dehydrogenation of Amines and Carbonyl Compounds Catalyzed by a Tetranuclear Ruthenium-μ-oxo-μ-hydroxo-hydride Complex [PDF]

, 2009
The tetranuclear ruthenium-μ-oxo-μ-hydroxo-hydride complex {[(PCy3)(CO)RuH]4(μ4-O)(μ3-OH)(μ2-OH)} (1) was found to be a highly effective catalyst for the transfer dehydrogenation of amines and carbonyl compounds. For example, the initial turnover rate of
Lee, Do W., Yi, Chae S.
core   +2 more sources

Spiro[cyclopropane-1,3′-indolin]-2′-one [PDF]

Acta Crystallographica Section E Structure Reports Online, 2011
In the title mol-ecule, C(10)H(9)NO, the dihedral angle between the mean plane of the cyclo-propane ring and the essentially planar [maximum deviation = 0.032 (2) Å] indole ring system is 87.65 (17)°. In the crystal, inter-molecular N-H⋯O hydrogen bonds link mol-ecules into one-dimensional chains along [100].
Yuan, Maosen, Wang, Qi, Zhang, Yuejun, Wang, Junru   +3 more
openaire   +2 more sources

3-[(E)-Benzylidene]indolin-2-one [PDF]

Acta Crystallographica Section E Structure Reports Online, 2012
In the title indolin-2-one derivative, C(15)H(11)NO, the phenyl ring and the oxoindoline fused-ring system (r.m.s. deviation = 0.011 Å) are aligned at 48.52 (6)°. In the crystal, inversion-related mol-ecules form an N-H⋯O hydrogen-bonded dimer via an eight-membered {⋯HNCO}(2) synthon.
Abdullah M. Asiri, Mohie E. M. Zayed, Seik Weng Ng, Edward R. T. Tiekink   +3 more
openaire   +3 more sources

Promiscuity‐Guided Enzyme Evolution via Substrate Multiplexed Screening

Angewandte Chemie, EarlyView.
Through historical context and recent examples, this Minireview summarizes the strengths, limitations, and practical considerations for the implementation of substrate multiplexed screening (SUMS) in enzyme evolution. ABSTRACT An enzyme's ability to react with diverse substrates while maintaining high yield and selectivity, termed “substrate ...
Holly A. Weilbaker, Meghan E. Campbell, Peyton M. Higgins, Andrew R. Buller   +3 more
wiley   +2 more sources

1,1′-(Hexane-1,6-diyl)bis(indoline-2,3-dione)

IUCrData, 2016
The molecule of the title compound, C22H20N2O4, is situated on a crystallographic centre of symmetry. The two indoline-2,3-dione fragments are linked by a hexylene group at each N atom.
Fatima Zahrae Qachchachi, Youssef Kandri Rodi, Amal Haoudi, El Mokhtar Essassi, Frédéric Capet, Hafid Zouihri   +5 more
doaj   +1 more source

Zinc-Catalyzed Enantioselective [3 + 3] Annulation for Synthesis of Chiral Spiro[indoline-3,4′-thiopyrano[2,3-b]indole] Derivatives

Molecules, 2023
With a dinuclear zinc-ProPhenol complex as a catalyst, an efficient and novel [3 + 3] annulation of indoline-2-thiones and isatylidene malononitriles has been successfully developed via the Brønsted base and Lewis acid cooperative activation model.
Tian-Tian Liu, Yu Chen, Guang-Jian Mei, Yuan-Zhao Hua, Shi-Kun Jia, Min-Can Wang   +5 more
doaj   +1 more source

Photochromic spiropyran monolithic polymers: Molecular photo-controllable electroosmotic pumps for micro-fluidic devices [PDF]

, 2010
A novel photo-controllable micro-fluidic electroosmotic pump based on spiropyran monolithic polymers is presented here for the first time. Photochromic monolithic scaffolds have been synthesised within poly(tetrafluoroethylene) coated fused silica ...
Abele, Silvija, Benito-Lopez, Fernando, Byrne, Robert, Diamond, Dermot, Macka, Mirek, Nie, Fu-Qiang, Paull, Brett, Scarmagnani, Silvia, Slater, Conor, Walsh, Zarah   +9 more
core   +1 more source

Strategies Toward Accessing Enantioenriched (Hetero)Benzo‐Fused 5‐ and 6‐ Membered Rings via Intermolecular Carbometalation

Angewandte Chemie, EarlyView.
The use of transition‐metal catalysts and design of chiral ligands have allowed chemists to access highly functionalized benzofused 5‐ and 6‐ membered rings in high yield and enantioselectivity. A common strategy used relies on an intermolecular carbometalation across alkynes and olefins, usually followed by a subsequent intramolecular carbometalation.
Clara Jans, Armaan Grewal, Xavier Abel‐Snape, Mark Lautens   +3 more
wiley   +2 more sources

A multiswitchable poly(terthiophene) bearing a spiropyran functionality: understanding photo and electrochemical control [PDF]

, 2011
An electroactive nitrospiropyran-substituted polyterthiophene, 2-(3,3′′-dimethylindoline-6′-nitrobenzospiropyranyl)ethyl 4,4′′-didecyloxy-2,2′:5′,2′′-terthiophene-3′-acetate, has been synthesized for the first time.
Breukers, Robert, Byrne, Robert, Dennany, Lynn, Diamond, Dermot, Gambhir, Sanjeev, Higgins, Michael, Officer, David, Wagner, Klaudia, Wagner, Pawel, Wallace, Gordon, Zanoni, Michele   +10 more
core   +1 more source