Results 11 to 20 of about 451 (130)

Synthesis of functionalized spiro[indoline-3,4’-pyridines] and spiro[indoline-3,4’-pyridinones] via one-pot four-component reactions

Beilstein Journal of Organic Chemistry, 2013
In the presence of triethylamine as catalyst, the one-pot four-component reactions of arylamines, methyl propiolate, isatin and malononitrile afforded the functionalized spiro[indoline-3,4’-pyridine] derivatives in good yields.
Li-Juan Zhang, Qun Wu, Jing Sun, Chao-Guo Yan   +3 more
doaj   +1 more source

Methyl 2-(5-chloro-1-methyl-2-oxo-2,3-dihydro-1H-indol-3-ylidene)acetate

Acta Crystallographica Section E, 2013
The title compound, C12H10ClNO3, the indoline ring system is essentially planar, with a maximum deviation of 0.009 Å for the N atom. The indoline ring and acetate group are essentially coplanar, with a maximum deviation of 0.086 Å ...
Piskala Subburaman Kannan, PanneerSelvam Yuvaraj, Karthikeyan Manivannan, Boreddy S. R. Reddy, A. SubbiahPandi   +4 more
doaj   +1 more source

Synthesis and biological activities of some indoline derivatives [PDF]

Journal of the Serbian Chemical Society, 2009
The reaction of indoline with a substituted benzoyl chloride in the presence of K2CO3 in THF gave compound 4. Compound 4 was subjected to chlorosulphonation to obtain compound 5.
Rode Milind A., Rindhe Sahebrao S., Karale Bhausaheb K.   +2 more
doaj   +3 more sources

Synthesis, characterization and evaluation of antidiabetic activity of novel indoline derivatives

Bangladesh Journal of Pharmacology, 2017
Series of indoline derivatives were synthesized using N-(4-aminophenyl)indoline-1-carbothiamide as a precursor. The confirmation of synthesized compounds was done by 1H-NMR, 13C-NMR, LC-MS (ESI) and FT-IR.
Dhineshkumar Manoharan, Kannan Kulanthai, Gnanavel Sadhasivam, Vijayan Raji, Paalvannan Thayumanavan   +4 more
doaj   +1 more source

5-Chloro-1-methylindoline-2,3-dione

IUCrData, 2016
The title molecule, C9H6ClNO2, is almost planar, with an r.m.s. deviation of the fitted non-hydrogen atoms of 0.0922 (19) Å. In the crystal, molecules are connected through methyl-C—H...O(carbonyl) interactions into supramolecular helical chains along ...
Zineb Tribak, Youssef Kandri Rodi, Amal Haoudi, El Mokhtar Essassi, Frédéric Capet, Hafid Zouihri   +5 more
doaj   +1 more source

Crystal structure of 7′-(4-chlorophenyl)-2′′-(4-methoxyphenyl)-7′,7a',7′′,8′′-tetrahydro-1′H,3′H,5′′H-dispiro[indoline-3,5′-pyrrolo[1,2-c]thiazole-6′,6′′-quinoline]-2,5′′-dione and an unknown solvent

Acta Crystallographica Section E: Crystallographic Communications, 2019
The asymmetric unit of the title compound, C34H28ClN3O3S, contains two independent molecules (A and B). They differ essentially in the orientation of the 4-methoxyphenyl ring with respect to the pyridine ring of the quinoline moiety; this dihedral angle ...
R. Vishnupriya, M. Venkateshan, J. Suresh, R. V. Sumesh, R. Ranjith Kumar, P. L. Nilantha Lakshman   +5 more
doaj   +1 more source

Design, Synthesis of New 1,2,4-Triazole/1,3,4-Thiadiazole with Spiroindoline, Imidazo[4,5-b]quinoxaline and Thieno[2,3-d]pyrimidine from Isatin Derivatives as Anticancer Agents

Molecules, 2022
The current work aims to design and synthesis a new series of isatin derivatives and greatly enhances their cytotoxic activity. The derivatives 3-((bromophenyl) imino)-1-(morpholino (pyridine) methyl) indolin-2-one, 2-((oxoindoline) amino) benzoic acid ...
Ameen Ali Abu-Hashem, Sami A. Al-Hussain
doaj   +1 more source

1,1′-(Hexane-1,6-diyl)bis(indoline-2,3-dione)

IUCrData, 2016
The molecule of the title compound, C22H20N2O4, is situated on a crystallographic centre of symmetry. The two indoline-2,3-dione fragments are linked by a hexylene group at each N atom.
Fatima Zahrae Qachchachi, Youssef Kandri Rodi, Amal Haoudi, El Mokhtar Essassi, Frédéric Capet, Hafid Zouihri   +5 more
doaj   +1 more source

Zinc-Catalyzed Enantioselective [3 + 3] Annulation for Synthesis of Chiral Spiro[indoline-3,4′-thiopyrano[2,3-b]indole] Derivatives

Molecules, 2023
With a dinuclear zinc-ProPhenol complex as a catalyst, an efficient and novel [3 + 3] annulation of indoline-2-thiones and isatylidene malononitriles has been successfully developed via the Brønsted base and Lewis acid cooperative activation model.
Tian-Tian Liu, Yu Chen, Guang-Jian Mei, Yuan-Zhao Hua, Shi-Kun Jia, Min-Can Wang   +5 more
doaj   +1 more source

An Enantioselective Alkene Aminoarylation to Form Chiral Indolines via Electrostatically‐Directed Palladium Catalysis

Angewandte Chemie, Volume 138, Issue 34, 17 August 2026.
Enantioselective aminoarylation of ortho‐allyl anilines is achieved under mild conditions. Key to success is the electrostatically‐directed nature of the key aminopalladation step, achieved by using the sulfonated chiral ligand sSPhos on palladium. A detailed study of electronic trends allows tuning of the sulfonamide protecting group to enable good ...
Max Kadarauch, Paul T. Jirsch, H. Erik Diepers, Hamzah Sharif, Robert J. Phipps   +4 more
wiley   +2 more sources