Results 21 to 30 of about 451 (130)

1-[(2E)-3-Phenylprop-2-en-1-yl]-1H-indole-2,3-dione

IUCrData, 2016
In the title compound, C17H13NO2, the indole ring is essentially planar (r.m.s. deviation = 0.027 Å) and is oriented at an angle of 69.33 (7)° with respect to the phenyl ring.
Fatima Zahrae Qachchachi, Youssef Kandri Rodi, Amal Haoudi, El Mokhtar Essassi, Frédéric Capet, Hafid Zouihri   +5 more
doaj   +1 more source

Transition Metal‐Free Heteroarene Insertion Into C─C Bonds of Benzocyclobutenones

Angewandte Chemie, Volume 138, Issue 32, 3 August 2026.
A transition metal‐free insertion of five‐membered heteroarenes into the C─C bonds of benzocyclobutenones has been achieved under mild and operationally simple conditions. This method provides an efficient and modular approach to access fused partially saturated hetero‐polycyclic scaffolds that exist in many bioactive molecules.
Cole J. Wagner, Guangbin Dong
wiley   +2 more sources

Crystal structure of 1′-(prop-2-yn-1-yl)-1,4-dihydrospiro[benzo[d][1,3]oxazine-2,3′-indolin]-2′-one

Acta Crystallographica Section E: Crystallographic Communications, 2015
In the title compound, C18H14N2O2, the six-membered oxazine ring adopts a half-chair conformation and its mean plane makes a dihedral angle of 83.23 (7)° with the pyrrolidine ring of the indoline ring system. In the crystal, molecules are linked via N—H..
Y. AaminaNaaz, J. Kamalraja, G. Vimala, P. T. Perumal, A. SubbiahPandi   +4 more
doaj   +1 more source

Discovery of aminopyridine-containing spiro derivatives as EGFR mutations inhibitors

Journal of Enzyme Inhibition and Medicinal Chemistry, 2019
Neratinib is an oral pan HER inhibitor, that irreversibly inhibits EGFR and HER2 and was proven to be effective against multiple EGFR mutations. In previous study, we reported spiro [indoline-3, 4′-piperidine]-2-ones as anticancer agents.
Lianbao Ye, Tao Zhao, Wenjun Du, Anhu Li, Wei Gao, Jingrong Li, Ling Wang, Weiqiang Chen   +7 more
doaj   +1 more source

Spiro[pyrrolidine-3,3′-oxindoles] and Their Indoline Analogues as New 5-HT6 Receptor Chemotypes

Molecules, 2017
Synthetic derivatives of spiro[pyrrolidinyl-3,3′-oxindole] alkaloids (coerulescine analogues) were investigated as new ligands for aminergic G-protein coupled receptors (GPCRs).
Ádám A. Kelemen, Grzegorz Satala, Andrzej J. Bojarski, György M. Keserű   +3 more
doaj   +1 more source

Organic photonic synaptic transistors for bionic vision: From spectral engineering to flexible intelligent perception

FlexMat, EarlyView.
Different wavelength photonic synapses are used for biomimetic visual applications. Abstract Bionic intelligent visual perception systems have significant application prospects in fields such as autonomous driving and robotics, medical imaging and auxiliary diagnosis, security and monitoring.
Longlong Jiang, Shan Wu, Silu Feng, Heyi Huang, Wangyu Wu, Hong Han, Yao Ni   +6 more
wiley   +1 more source

Crystal structure of ethyl 1′,5-dimethyl-2′′,3-dioxo-3H-dispiro[benzo[b]thiophene-2,3′-pyrrolidine-2′,3′′-indoline]-4′-carboxylate

Acta Crystallographica Section E: Crystallographic Communications, 2015
The title compound, C23H22N2O4S, crystallized with two independent molecules (A and B) in the asymmetric unit. They have very similar conformations with the pyrrolidine ring having a twisted conformation, on the Cspiro—Cspiro bond, in both molecules.
R. Raja, J. Govindaraj, M. Suresh, R. Raghunathan, A. SubbiahPandi   +4 more
doaj   +1 more source

MXene‐Based Flexible Memory and Neuromorphic Devices

Small, EarlyView.
The unique two‐dimensional structure, excellent electrical conductivity, and diverse surface groups of MXenes have garnered significant attention. Coupled with their exceptional flexibility, MXene‐based devices hold immense potential for flexible memory and neuromorphic systems. This review comprehensively discusses the fundamentals of flexible devices,
Yan Li, Guanglong Ding, Yongbiao Zhai, Ziyu Lv, Yan Yan, Shuangmei Xue, Kui Zhou, Meng Zhang, Yutong Zhang, Qi‐Jun Sun, Yi Liu, Vellaisamy A. L. Roy, Ye Zhou, Su‐Ting Han   +13 more
wiley   +1 more source

Photo‐Switched Catalytic Amyloids

Small, EarlyView.
Photo‐switched reversible hierarchical assembly of catalytic amyloid fibrils is accomplished by mixing an amphiphilic cross‐ß peptide with a merocyanine photo switch. The peptide monomers, comprising phenylalanine‐lysine repeats, do not self‐assemble in water because of the electrostatic repulsion.
Shubhra Kanti Bhaumik, Sisira Mambram Kunnath, Elad Arad, Einat Nativ‐Roth, Arunavo Chatterjee, Albert Batushansky, Nitzan Shauloff, Hanna Rapaport, Raz Jelinek   +8 more
wiley   +1 more source

1-Allyl-3′-phenyl-6′H-spiro[indoline-3,4′-isoxazolo[4′,5′:5,6]pyrido[2,3-d]pyrimidine]-2,5′,7′(8′H,9′H)-trione dimethyl sulfoxide monosolvate

IUCrData, 2017
In the title solvated compound, C24H17N5O4·C2H6OS, the solvent molecule, dimethyl sulfoxide, is linked to the title molecule by an N—H...O hydrogen bond. The pyridine ring adopts a twist-boat conformation.
P. Seethalakshmi, C. Palanivel
doaj   +1 more source