Results 41 to 50 of about 13,350 (226)

Tri( n -butyl)phosphine-promoted domino reaction for the efficient construction of spiro[cyclohexane-1,3'-indolines] and spiro[indoline-3,2'-furan-3',3''-indolines]

Beilstein Journal of Organic Chemistry, 2022
The tri( n -butyl)phosphine-catalyzed reaction of isatylidene malononitriles and bis-chalcones in chloroform at 65 °C afforded functionalized spiro[cyclohexane-1,3'-indolines] in good yields and with good diastereoselectivity. On the other hand, the tri( n
Hui Zheng, Ying Han, Jing Sun, Chao-Guo Yan   +3 more
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1-(2,6-Dichlorophenyl)indolin-2-one [PDF]

Acta Crystallographica Section E Structure Reports Online, 2009
In the mol-ecule of the title compound, C(14)H(9)Cl(2)NO, the planar indole ring system [with a maximum deviation of 0.020 (2) Å for the N atom] is oriented at a dihedral angle of 72.17 (3)° with respect to the phenyl ring. In the crystal structure, weak inter-molecular C-H⋯O hydrogen bonds link the mol-ecules.
Hanif, Muhammad, Rafiq, Muhammad, Saleem, Muhammad, Qadeer, Ghulam, Wong, Wai-Yeung   +4 more
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1-Allyl-3′-phenyl-6′H-spiro[indoline-3,4′-isoxazolo[4′,5′:5,6]pyrido[2,3-d]pyrimidine]-2,5′,7′(8′H,9′H)-trione dimethyl sulfoxide monosolvate

IUCrData, 2017
In the title solvated compound, C24H17N5O4·C2H6OS, the solvent molecule, dimethyl sulfoxide, is linked to the title molecule by an N—H...O hydrogen bond. The pyridine ring adopts a twist-boat conformation.
P. Seethalakshmi, C. Palanivel
doaj   +1 more source

Reversible low-light induced photoswitching of crowned spiropyran-DO3A complexed with gadolinium(III) ions. [PDF]

, 2012
Photoswitchable spiropyran has been conjugated to the crowned ring system DO3A, which improves its solubility in dipolar and polar media and stabilizes the merocyanine isomer. Adding the lanthanide ion gadolinium(III) to the macrocyclic ring system leads
Brueggemann, Chantal, Knoesen, André, Kruttwig, Klaus, L'etoile, Noelle, Louie, Angelique Y, Tu, Chuqiao, Yankelevich, Diego R   +6 more
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Synthesis of N‐Alkylated Indolines and Indoles from Indoline and Aliphatic Ketones

Journal of Heterocyclic Chemistry, 2015
A survey of redox aminations of indoline with aliphatic ketones using bismuth nitrate as catalyst is described. A reaction of an equivalent amount of indoline and aliphatic cyclic and acyclic ketones provides a mixture of excessive alkylated indole derivatives over typically redox isomerization and reductive alkylation pathways while using of the five ...
Bayindir, Sinan, Erdogan, Esra, Kilic, Haydar, Aydin, Omer, Saracoglu, Nurullah   +4 more
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1-Propyl-1H-indole-2,3-dione

IUCrData, 2016
In the title compound, C11H11NO2, the 1H-indole-2,3-dione unit is essentially planar, with an r.m.s. deviation of 0.0387 (13) Å. This plane makes a dihedral angle of 72.19 (17)° with the plane of the propyl substituent. In the crystal, chains propagating
Fatima Zahrae Qachchachi, Youssef Kandri Rodi, Amal Haoudi, El Mokhtar Essassi, Frédéric Capet, Hafid Zouihri   +5 more
doaj   +1 more source

Discovery of aminopyridine-containing spiro derivatives as EGFR mutations inhibitors

Journal of Enzyme Inhibition and Medicinal Chemistry, 2019
Neratinib is an oral pan HER inhibitor, that irreversibly inhibits EGFR and HER2 and was proven to be effective against multiple EGFR mutations. In previous study, we reported spiro [indoline-3, 4′-piperidine]-2-ones as anticancer agents.
Lianbao Ye, Tao Zhao, Wenjun Du, Anhu Li, Wei Gao, Jingrong Li, Ling Wang, Weiqiang Chen   +7 more
doaj   +1 more source

Crystal structures of 2-methoxyisoindoline-1,3-dione, 1,3-dioxoisoindolin-2-yl methyl carbonate and 1,3-dioxo-2,3-dihydro-1H-benzo[de]isoquinolin-2-yl methyl carbonate: three anticonvulsant compounds

Acta Crystallographica Section E, 2014
The title compounds, C9H7NO3, (1), C10H7NO5, (2), and C14H9NO5, (3), are three potentially anticonvulsant compounds. Compounds (1) and (2) are isoindoline derivatives and (3) is an isoquinoline derivative.
Fortune Ezemobi, Henry North, Kenneth R. Scott, Anthohy K. Wutoh, Ray J. Butcher   +4 more
doaj   +1 more source

Characterization of High-Performance Organic Dyes for Dye-Sensitized Solar Cell: A DFT/TDDFT Study [PDF]

, 2016
Dye-sensitized solar cell (DSSC) is currently a promising technology that makes solar energy efficient and cost-effective to harness. In DSSC, metal free dyes, such indoline-containing D149 and D205, are proved to be potential alternatives for ...
Hu, P., Huang, Meilan, Lambert, Christopher, Mao, Yu, Tao, Xia, Zheng, Yan-Zhen   +5 more
core   +1 more source

Spiro[1,3-dioxolane-2,3′-indolin]-2′-one [PDF]

Acta Crystallographica Section E Structure Reports Online, 2010
The title compound, C(10)H(9)NO(3), was synthesized by the condensation reaction of isatin (systematic name 1H-indole-2,3-dione) with glycol in presence of p-toluene-sulfonic acid. The indol-2-one ring system is essentially planar [N-C-C-C torsion angle = 3.1 (2)°], and the 1,3-dioxolane ring is slightly distorted.
Meng, Yan, Miao, Yanqing
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