Results 41 to 50 of about 451 (130)

Crystal structure and Hirshfeld surface analysis of 4′-(2-chlorophenyl)-1′-methyl-3′′-phenyl-7′′,8′′-dihydro-5′′H-dispiro[indoline-3,2′-pyrrolidine-3′,6′′-isoquinoline]-2,5′′-dione

open access: yesActa Crystallographica Section E: Crystallographic Communications, 2018
In the title dispiro compound, C32H26ClN3O2, the cyclohexanone ring of the isoquinoline unit has a distorted envelope conformation, with the methylene C atom adjacent to the spiro C atom as the flap.
R. Vishnupriya   +5 more
doaj   +1 more source

A New Indoline Rearrangement [PDF]

open access: yesCanadian Journal of Chemistry, 1972
The keto pyrrolidone 2 in the presence of acid produces the enamine 3a and the rearranged quinolone 4. Evidence is presented for the mechanism of this new rearrangement, the key step being a remarkably facile opening and reclosure of the indoline ring [Formula: see text] which even occurs in acetic acid.
Vinod Dave   +2 more
openaire   +1 more source

Unlocking Stereodefined Olefins by Z‐Selective Transition Metals‐catalyzed C−H Activations

open access: yesChemCatChem, Volume 18, Issue 15, 14 August 2026.
The synthesis of Z‐olefins is an important challenge in synthetic organic chemistry. Within this review, we report a comprehensive overview of transition metals‐catalyzed Z‐selective C–H activations of (hetero)arenes for the synthesis of stereodefined olefins.
Francesco Capranica   +2 more
wiley   +1 more source

Synthesis and antimicrobial evaluation of spiro compound containing 1,2,4-triazole and isatin

open access: yesOrbital: The Electronic Journal of Chemistry, 2011
The synthesis of 6'-Phenyl-4'-thioxo-3'-(4H-1,2,4-triazole-4-yl)-3',4'-dihydrospiro [Indoline-3,2'-[1,3,5]oxadiazine]-2-one (5a-h) is carried out by two a step reaction, beginning with acid catalyzed condensation of 4H-1,2,4-triazole-4-amine (1)
Visha P. Modi   +2 more
doaj   +1 more source

Catalytic Deuteration of Amines in Water (D2O) With Ir, Ru, and Rh Pentamethylcyclopentadienyl Dioxime Complexes

open access: yesChemistryEurope, Volume 4, Issue 8, August 2026.
A new family of pentamethylcyclopentadienyl (C5Me5, Cp*) iridium(III), rhodium(III), and ruthenium(III) complexes bearing bidentate 1,2‐dioxime ligands was developed and their catalytic performances were evaluated in the hydrogen‐borrowing‐type H/D exchange of amines using D2O as both solvent and deuterium source. Iridium derivatives achieved excellent
Francesco Taglieri   +8 more
wiley   +1 more source

2′-Amino-5′-benzoyl-5-bromo-6′-methyl-2-oxospiro[indoline-3,4′-pyran]-3′-carbonitrile

open access: yesIUCrData
In the title compound, C21H14BrN3O3, the indoline ring system is almost planar, while the pyran ring is in flattened-boat conformation. In the crystal, N—H...O and N—H...N hydrogen bonds link the molecules, enclosing R22(8) and R22(12) ring motifs, into (
Farid N. Naghiyev   +4 more
doaj   +1 more source

Mechanochemistry as an Emerging Tool for Organofluorine Chemistry

open access: yesChemistry–Methods, Volume 6, Issue 8, August 2026.
Fluorinated scaffolds are central across many areas of chemistry, driving the demand for efficient and sustainable synthetic methods. Mechanochemistry has emerged as a powerful alternative to conventional approaches, offering reduced environmental impact, shorter reaction times, and unique reactivity and selectivity.
Marie Caldiero   +3 more
wiley   +1 more source

5-Bromo-1-nonylindoline-2,3-dione

open access: yesIUCrData, 2016
In the title compound, C17H22BrNO2, the indoline ring system, the two ketone O atoms and the Br atom are nearly coplanar, with an r.m.s. deviation of 0.029 Å.
Yassine Kharbach   +4 more
doaj   +1 more source

Design, Synthesis, X‐Ray Crystallographic Characterization, Anticholinesterase and Antioxidant Evaluation, and Molecular Modeling of Novel Dispiroindene‐Pyrrolidine Derivatives as Multifunctional Anti‐Alzheimer Agents

open access: yesDrug Development Research, Volume 87, Issue 5, August 2026.
ABSTRACT A novel series of 5‐chloro‐N‐alkyl‐1′,1″‐dimethyl‐4′‐aryldispiro[indene‐2,3′‐pyrrolidine‐2′,3″‐indoline]−1,2″(3H)‐diones (4a–r) was rationally designed and synthesized via a one‐pot multicomponent reaction of N‐alkylated 5‐chloroisatin derivatives, 2‐(arylmethylidene)−2,3‐dihydro‐1H‐inden‐1‐ones (2a–i), and sarcosine (3).
Aisha A. Alsfouk   +7 more
wiley   +1 more source

Crystal structure determination as part of an undergraduate laboratory experiment: 1′,3′,3′-trimethylspiro[chromene-2,2′-indoline] and 1′,3′,3′-trimethyl-4-[(E)-(1,3,3-trimethylindolin-2-ylidene)methyl]spiro[chroman-2,2′-indoline]

open access: yesActa Crystallographica Section E: Crystallographic Communications, 2016
The crystal structures of the title compounds, C19H19NO and C31H34N2O, were determined as part of an experiment in an undergraduate teaching laboratory that demonstrates the relationship between molecular structure and function.
Joseph O. S. Beckett   +5 more
doaj   +1 more source

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