Results 51 to 60 of about 451 (130)
Trifluoromethylation‐Induced Lactonization: A Novel Transformation of Unsaturated Carboxylic Acids
ChemistryOpen, Volume 15, Issue 8, August 2026.Fluorinated drugs often contain trifluoromethyl groups. The increasing importance of such drugs has resulted in more and more attention toward new or improved trifluoromethylation reactions. This review discusses possible reaction mechanisms and existing methods for one such process, trifluoromethylation‐induced lactonization, a distant relative of the
Attila M. Remete
wiley +1 more source
Molecules, 2011 The n-butyramido, isobutyramido, benzamido, and furancarboxamido functions profoundly modulate the electronics of the stilbene olefinic and NH groups and the corresponding radical cations in ways that influence the efficiency of the cyclization due ...
Noel Francis Thomas +7 more
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Angewandte Chemie, Volume 138, Issue 31, 27 July 2026.Die Kontrolle biologischer Systeme mit organischen Chromophoren hat sich zu einer vielversprechenden Strategie entwickelt und findet Anwendung von der chemischen Biologie bis hin zur Medizin. Die Komplexität von In‐vivo‐Systemen lässt sich jedoch nicht mit nur einer einzigen Lichtwellenlänge adäquat abbilden.
Nadja A. Simeth
wiley +1 more source
Chiral Aminophosphines as Catalysts for Enantioselective Double-Michael Indoline Syntheses
Molecules, 2012 The bisphosphine-catalyzed double-Michael addition of dinucleophiles to electron-deficient acetylenes is an efficient process for the synthesis of many nitrogen-containing heterocycles.
Ohyun Kwon, San N. Khong
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Toward Chromoselective Transformations in Biological Systems: Perspectives and Challenges
Angewandte Chemie International Edition, Volume 65, Issue 31, 27 July 2026.Controlling biological systems with small‐molecule chromophores has evolved into a powerful strategy and is applied from chemical biology to medicine. However, the complexity of in vivo systems cannot be matched by a single wavelength of light. Developing methods to combine and individually control multiple chromophores is crucial.
Nadja A. Simeth
wiley +1 more source
1-Benzyl-5-chloroindoline-2,3-dione
IUCrData, 2016 The title compound, C15H10ClNO2, crystallizes with two molecules (A and B) in the asymmetric unit, which have almost identical conformations (r.m.s. overlay fit = 0.057 Å).
Zineb Tribak +5 more
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Acta Crystallographica Section E: Crystallographic Communications, 2015 In the title compound, C23H20N2O4S2, the central pyrrolidine ring adopts an envelope conformation with the spiro C atom, shared with the benzothiophene ring system, as the flap.
M. P. Savithri +4 more
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An Ugi–Joullié Platform for Medicinally Relevant 1,4‐Dihydrobenzothiazines
ChemMedChem, Volume 21, Issue 13, 14 July 2026.A series of benzothiazine derivatives was efficiently synthesized via an UJ‐2CR of a preformed imine and diverse isocyanides. The method features mild, room‐temperature conditions, broad functional‐group tolerance, and scalability, enabling rapid access to a chemically diverse library of 19 adducts with potential for further medicinal chemistry ...
Xiaofang Lei +9 more
wiley +1 more source
1-Allyl-5-chloroindoline-2,3-dione
IUCrData, 2016 In the title compound, C11H8ClNO2, the allyl side chain is almost perpendicular to the 5-chloroindoline-2,3-dione ring system, with a dihedral angle of 88.0 (3)°.
Zineb Tribak +5 more
doaj +1 more source
Acta Crystallographica Section E: Crystallographic Communications, 2015 In the title compound, C25H23FN2O4S, the fused piperidine ring of the octahydroindolizine ring system adopts a chair conformation and the five-membered ring has a twisted conformation on the N—C(spiro) bond.
R. Raja +4 more
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