Results 61 to 70 of about 451 (130)

1-{[3-(Thiophen-2-yl)-4,5-dihydro-1,2-oxazol-5-yl]methyl}-2,3-dihydro-1H-indole-2,3-dione

IUCrData, 2017
In the title compound, C16H12N2O3S, the indoline and thiophene rings are inclined to one another by 2.01 (2)°. The isoxazole ring adopts an envelope conformation, with the methine C atom as the flap, and its mean plane is inclined to the thiophene and ...
Ibtissam Rayni, Youness El Bakri, Jihad Sebhaoui, Khadija El Bourakadi, El Mokhtar Essassi, Joel T. Mague   +5 more
doaj   +1 more source

5′-Nitro-1,4-dihydrospiro[3,1-benzoxazine-2,3′-indolin]-2′-one

IUCrData, 2018
In the title compound, C15H11N3O4, the six-membered oxazine ring adopts a half-chair conformation and is oriented at an angle of 78.63 (9)° with respect to the pyrrolidine ring of the indoline ring system, which adopts an envelope conformation. The spiro
Y. AaminaNaaz, Jayabal Kamalraja, Paramasivam T. Perumal, A. SubbiahPandi   +3 more
doaj   +1 more source

Crystal structure of methyl 1-methyl-2-oxospiro[indoline-3,2′-oxirane]-3′-carboxylate

Acta Crystallographica Section E: Crystallographic Communications, 2015
In the title compound, C12H11NO4, the dihedral angle between the indole ring system (r.m.s. deviation = 0.019 Å) and the oxirane ring is 88.8 (2)°. The oxirane O atom and the bridging ester O atom are in an approximate syn conformation [O—C—C—O = −25.4 ...
M. P. Savithri, P. S. Yuvaraj, B. S. R. Reddy, R. Raja, A. SubbiahPandi   +4 more
doaj   +1 more source

2′-Ethoxy-1,3,3-trimethylspiro[indoline-2,3′-3H-naphtho[2,1-b][1,4]oxazine]

Acta Crystallographica Section E, 2010
In the title compound, C24H24N2O2, the five-membered ring of the indoline ring system adopts an envelope conformation with the spiro C atom at the flap.
Jian Lin, Wenxiang Chai, Yunyun Yang, Jiaojiao He, Kangying Shu   +4 more
doaj   +1 more source

3-(Diphenylmethylidene)indolin-2-one

Acta Crystallographica Section E, 2011
The title molecule, C21H15NO, has an indoline-2-one and two benzene substituent groups which are arranged in a propeller-like fashion around the central C atom.
Maosen Yuan, Qi Wang, Shujun Zhang, Peng Gao, Junru Wang   +4 more
doaj   +1 more source

Synthesis and crystal structures of 5'-phenylspiro[indoline-3, 2'-pyrrolidin]-2-one derivatives

Chemistry Central Journal, 2011
Background The spiro- indole-pyrrolidine ring system is a frequently encountered structural motif in many biologically important and pharmacologically relevant alkaloids. The derivatives of spirooxindole ring systems are used as antimicrobial, antitumour
Perumal Subbu, Sivamani Jeyaraman, Rajesh Stephen, Sundar Jeyaperumal, Natarajan Subramanian   +4 more
doaj   +1 more source

Methyl isocyanide as a convertible functional group for the synthesis of spirocyclic oxindole γ-lactams via post-Ugi-4CR/transamidation/cyclization in a one-pot, three-step sequence

Beilstein Journal of Organic Chemistry, 2018
The synthesis of spiro[indoline-3,2'-pyrrole]-2,5'(1'H)-diones and spiro[indoline-3,2'-pyrrolidine]-2,5'-diones, via a post-Ugi-domino transamidation/cyclization sequential process, has been achieved in three sequential steps utilizing a one-pot reaction
Amarendar Reddy Maddirala, Peter R. Andreana   +1 more
doaj   +1 more source

Additive-assisted regioselective 1,3-dipolar cycloaddition of azomethine ylides with benzylideneacetone

Beilstein Journal of Organic Chemistry, 2014
1,3-Dipolar cycloadditions of isatins, benzylamine and benzylideneacetones were studied to prepare a series of novel spiropyrrolidine-oxindoles – 4′-acetyl-3′,5′-diarylspiro[indoline-3,2′-pyrrolidin]-2-ones and 3′-acetyl-4′,5′-diarylspiro[indoline-3,2 ...
Chuqin Peng, Jiwei Ren, Jun-An Xiao, Honggang Zhang, Hua Yang, Yiming Luo   +5 more
doaj   +1 more source

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Diastereoselective synthesis of functionalized spiro[cyclopropane-1,3′-indolines] and spiro[indoline-3,1′-cyclopropane-2′,3″-indolines]

Tetrahedron, 2016
In the presence of hexamethylphosphorous triamide, the reaction of isatin with arylidene pivaloylacetonitriles in dry methylene dichloride afforded functionalized spiro[cyclopropane-1,3′-indolines] in good yields and with high diastereoselectivity.
Chao-Guo Yan
exaly   +3 more sources

Reduction of Indolin‐2‐ones and Desulfurization of Indoline‐2‐thiones to Indoline and Indole Derivatives

Helvetica Chimica Acta, 1990
AbstractReduction of indolin‐2‐ones with lithium aluminium hydride (LAH) or diisobutylaluminum hydride (DIBAL) and desulfurization of indoline‐2‐thiones with Raney‐Ni were investigated. Treatment of indoline‐2‐ones 1 with LAH or DIBAL yield indoles 4 and/or indolines 3 in moderate‐to high yield depending on the substituents at N and C(3) of 1. Indoline‐
Takehiko Nishio, Norikazu Okuda, Choji Kashima   +2 more
openaire   +2 more sources