Highly efficient electrochemiluminescence of quinoline and isoquinoline in aqueous solution
Electrochemistry Communications, 2019 This paper reports for the first time the strong cathodic electrochemiluminescence (ECL) behavior of quinoline, isoquinoline and their derivatives in aqueous solution with K2S2O8 as coreactant. The effects of K2S2O8 concentration, pH and scan rate on the
Xiangxiang Qin, Yinggui Zhu
exaly +4 more sources
Research Progress on Neuroprotective Effects of Isoquinoline Alkaloids
Molecules, 2023 Neuronal injury and apoptosis are important causes of the occurrence and development of many neurodegenerative diseases, such as cerebral ischemia, Alzheimer’s disease, and Parkinson’s disease. Although the detailed mechanism of some diseases is unknown,
Shuze Dong, Benhan Xiang
exaly +4 more sources
Recent Advances in Synthetic Isoquinoline-Based Derivatives in Drug Design [PDF]
MoleculesCompounds based on an isoquinoline scaffold (benzo[c]pyridine) display a broad spectrum of biological activities. In recent years, studies have focused mainly on their anticancer properties.
Łukasz Balewski, Anita Kornicka
doaj +3 more sources
Recent Advances in the Synthesis of Isoquinoline-Fused Benzimidazoles
Molecules, 2022 This review includes recent developments in the synthesis of benzo[4,5]imidazo[2,1-a]isoquinolines with particular attention given to categorizing protocols based on the structural features of the ring architecture and crystallographically characterized ...
Kraig Wheeler +2 more
exaly +3 more sources
Synthesis and Antifungal Evaluation of Isoquinoline-3-amide Derivatives Containing a Phenoxypyridine Moiety for Plant Protection. [PDF]
Chem BiodiversThe splicing of phenoxypyridine moieties to isoquinolin‐3‐carboxylic acid enhanced its biological activity against plant pathogenic fungi. Among target compounds, compound X6 demonstrated significant antifungal activity against Botrytis cinerea in vitro and in vivo assays, Molecular docking, molecular dynamics simulations, as well as SDH enzyme assay ...
Zhang J +7 more
europepmc +2 more sources
SYNTHESES OF ISOQUINOLINE DERIVATIVES USING 1-(LITHIO METHYL) ISOQUINOLINE.
, 1957 SYNTHESES OF ISOQUINOLINE DERIVATIVES USING 1-(LITHIO METHYL ...
JOSEPH GERALD. CANNON (7995041)
core +6 more sources
Synthesis and Anti-HIV Activity of a Novel Series of Isoquinoline-Based CXCR4 Antagonists
Molecules, 2021 An expansion of the structure–activity relationship study of CXCR4 antagonists led to the synthesis of a series of isoquinolines, bearing a tetrahydroquinoline or a 3-methylpyridinyl moiety as head group.
Mastaneh Safarnejad Shad +6 more
doaj +1 more source
Dess–Martin Periodinane-Mediated Oxidative Coupling Reaction of Isoquinoline with Benzyl Bromide
Molecules, 2023 Dess–Martin periodinane (DMP) is a broadly applicable oxidant in chemical synthesis. In this work, an efficient and convenient synthesis of N-substituted isoquinolinone derivatives mediated by DMP was achieved through the oxidative coupling reaction of ...
Chunmei Yang +5 more
doaj +1 more source
Isoquinoline-Based Biaryls as a Robust Scaffold for Microtubule Inhibitors [PDF]
, 2019 We here report the discovery of isoquinoline-based biaryls as a new scaffold for colchicine domain tubulin inhibitors. Colchicine domain inhibitors comprise a structurally diverse class of compounds offering highly desirable cytotoxic and vascular ...
Carina Glas (7138379) +8 more
core +3 more sources
Beilstein Journal of Organic Chemistry, 2023 The three-component reaction of isoquinolines, dialkyl acetylenedicarboxylates, and 5,6-unsubstituted 1,4-dihydropyridines in acetonitrile at room temperature afforded functionalized isoquinolino[1,2-f][1,6]naphthyridines in good yields and with high ...
Xiu-Yu Chen +4 more
doaj +1 more source