Results 11 to 20 of about 16,989 (195)

Crystal structure of 7′-(4-chlorophenyl)-2′′-(4-methoxyphenyl)-7′,7a',7′′,8′′-tetrahydro-1′H,3′H,5′′H-dispiro[indoline-3,5′-pyrrolo[1,2-c]thiazole-6′,6′′-quinoline]-2,5′′-dione and an unknown solvent

Acta Crystallographica Section E: Crystallographic Communications, 2019
The asymmetric unit of the title compound, C34H28ClN3O3S, contains two independent molecules (A and B). They differ essentially in the orientation of the 4-methoxyphenyl ring with respect to the pyridine ring of the quinoline moiety; this dihedral angle ...
R. Vishnupriya, M. Venkateshan, J. Suresh, R. V. Sumesh, R. Ranjith Kumar, P. L. Nilantha Lakshman   +5 more
doaj   +1 more source

Silver-Catalyzed Cascade Cyclization of Amino-NH-1,2,3-Triazoles with 2-Alkynylbenzaldehydes: An Access to Pentacyclic Fused Triazoles

Molecules, 2022
An operationally simple Ag(I)-catalyzed approach for the synthesis of isoquinoline and quinazoline fused 1,2,3-triazoles was developed by a condensation and amination cyclization cascade of amino-NH-1,2,3-triazoles with 2-alkynylbenzaldehydes involving ...
Shuitao Zhang, Jianxin Li, Tiebo Xiao, Baomin Yang, Yubo Jiang   +4 more
doaj   +1 more source

Efficient Synthesis of Isoquinoline Derivatives through Sequential Cyclization–Deoxygenation Reaction of 2-Alkynylbenzaldoximes

SynOpen, 2022
We describe a novel, simple, robust, and efficient cyclization/deoxygenation approach for the synthesis of functionalized isoquinoline derivatives. Over the course of continued studies on o-alkynylbenzaldoxime cyclization reactions, the formation of ...
Mojtaba Ayoubi, Ali Nikbakht, Kamran Amiri, Alireza Abbasi Kejani, Hossein Zahedian Tejeneki, Saeed Balalaie   +5 more
doaj   +1 more source

Spiropyran-Isoquinoline Dyad as a Dual Chemosensor for Co(II) and In(III) Detection

Molecules, 2017
Spiropyran derivatives have been studied as light-regulated chemosensors for a variety of metal cations and anions, but there is little research on chemosensors that simultaneously detect multiple metal cations.
Yong-Min Kho, Eun Ju Shin
doaj   +1 more source

Isolation of Alkaloid Compounds from Ethanol Extract of Rimpang Galang Merah (Alpinia purpurata (Vielli) K. Schum) and nanoparticle production from its Alkaloid Extract. Comparative Study of Antibacterial Properties on Staphylococcus aureus and Eschericia

Jurnal Kimia Sains dan Aplikasi, 2018
Isolation of alkaloid compounds from ethanol extract of red galangal rhizomes to compare their antibacterial properties with extracts formed into nanoparticles has been performed.
Vatara Artanta Silalahi, Enny Fachriyah, Pratama Jujur Wibawa   +2 more
doaj   +1 more source

Methyl 2-{[(6S*,7R*,8S*)-7-acetyl-8-(4-chlorophenyl)-4-cyano-6-hydroxy-1,6-dimethyl-5,6,7,8-tetrahydroisoquinolin-3-yl]sulfanyl}acetate

IUCrData, 2017
In the title compound, C23H23ClN2O4S, the 4-chlorophenyl ring is inclined to the pyridine ring of the isoquinoline group by 71.86 (13)°. In the crystal, molecules are linked by pairs of O—H...O hydrogen bonds, forming inversion dimers, which stack along ...
Joel T. Mague, Elham A. Al-Taifi, Shaaban K. Mohamed, Mehmet Akkurt, Etify A. Bakhite   +4 more
doaj   +1 more source

New (Iso)quinolinyl-pyridine-2,6-dicarboxamide G-Quadruplex Stabilizers. A Structure-Activity Relationship Study

Pharmaceuticals, 2021
G-quadruplex (G4)-interactive small molecules have a wide range of potential applications, not only as drugs, but also as sensors of quadruplex structures.
Enrico Cadoni, Pedro R. Magalhães, Rita M. Emídio, Eduarda Mendes, Jorge Vítor, Josué Carvalho, Carla Cruz, Bruno L. Victor, Alexandra Paulo   +8 more
doaj   +1 more source

Iridium‐Catalyzed Ionic Hydrogenation of Multi‐Aza Heterocycles

Angewandte Chemie, EarlyView.
Saturated nitrogen‐containing heterocycles are ubiquitous in bioactive molecules and are thus attractive synthetic targets. A readily accessible cyclometalated iridium(III) complex reduces 14 different aromatic aza heterocycles to (partially)saturated multi aza‐heterocycles enlarging accessible chemical space while displaying high tolerance toward ...
Arthur Despois, Nicolai Cramer
wiley   +2 more sources

Single‐Atom Iron‐Catalyzed Oxidative Esterification: From Methylarenes to the Upcycling of Polystyrene and Lignin‐Derived Feedstocks

Angewandte Chemie, EarlyView.
Heterogeneous iron‐catalyzed environmentally benign and sustainable CH‐oxidative esterification methodology has been developed for the synthesis of esters. This challenging reaction has been achieved by the rational design of specific single atom iron‐based catalyst with Fe‐N4 active centers, which empowered the oxidative esterification of methyl and ...
Zhuang Ma, Binyu Zhang, Hui Yang, Yue Hu, Junzheng Yu, Yanbin Cui, Jun Zhao, Matthias Beller, Rajenahally V. Jagadeesh   +8 more
wiley   +2 more sources

Can Isoquinoline Alkaloids Affect Platelet Aggregation in Whole Human Blood?

Toxins, 2022
Isoquinoline alkaloids have multiple biological activities, which might be associated with positive pharmacological effects as well as negative adverse reactions.
Mst Shamima Parvin, Marcel Hrubša, Jaka Fadraersada, Alejandro Carazo, Jana Karlíčková, Lucie Cahlíková, Jakub Chlebek, Kateřina Macáková, Přemysl Mladěnka   +8 more
doaj   +1 more source