Results 31 to 40 of about 16,989 (195)

Facile Synthesis of 3-Substituted Thiazolo[2,3-α]tetrahydroisoquinolines

Molecules, 2021
It was found that 4-hydroxy-2-butenoic ester (11) could not react with 3,4-dihydro-isoquinoline (4a). Individual addition reactions of γ-mercapto-α,β-unsaturated esters (18) and -unsaturated amide (19) with 3,4-dihydroisoquinolines (4) were carried out ...
Sheng-Han Huang, Wan-Yu Huang, Guo-Lun Zhang, Te-Fang Yang   +3 more
doaj   +1 more source

Dissociative Photoionization of Quinoline and Isoquinoline [PDF]

The Journal of Physical Chemistry A, 2015
Two nitrogen-containing polycyclic aromatic hydrocarbon isomers of C9H7N composition, quinoline, and isoquinoline have been studied by imaging photoelectron photoion coincidence spectroscopy at the VUV beamline of the Swiss Light Source. High resolution threshold photoelectron spectra have been recorded and are interpreted applying a Franck-Condon ...
Bouwman, J., Sztáray, B., Oomens, J., Hemberger, P., Bodi, A.   +4 more
openaire   +5 more sources

Biosynthesis of Isoquinoline Alkaloids [PDF]

Planta Medica, 1979
The isoquinoline alkaloids and their biosynthetic relatives include many compounds which show important physiological properties in animals: dopamine, mescaline, morphine, papaverine, and narcotine are pertinent examples. The biosynthetic routes to the members of this family start from the essential aminoacids tyrosine or phenylalanine. Decarboxylation
openaire   +2 more sources

Synthesis of New β-enaminones of Isoquinolines with 5,5-dimethyl-cyclohexanedione

Molbank, 2008
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Stoyanka Nikolova, Iliyan Ivanov
doaj   +1 more source

Stereochemistry of the methylidene-bridged quinazoline-isoquinoline alkaloid 3-{[6,7-dimethoxy-1-(4-nitrophenyl)-1,2,3,4-tetrahydroisoquinolin-2-yl]methylidene}-1,2,3,9-tetrahydropyrrolo[2,1-b]quinazolin-9-one methanol monosolvate

Acta Crystallographica Section E: Crystallographic Communications, 2020
Two potentially bioactive fragments, namely a tricyclic quinazoline derivative with an exocyclic alkene moiety and a substituted isoquinoline, are coupled to give 3-{[6,7-dimethoxy-1-(4-nitrophenyl)-1,2,3,4-tetrahydroisoquinolin-2-yl]methylidene}-1,2,3,9-
Akmal Tojiboev, Sherzod Zhurakulov, Valentina Vinogradova, Ulli Englert, Ruimin Wang   +4 more
doaj   +1 more source

A Molecular Engineering Strategy to Fine‐Tune Phototoxicity of AIE Probes for Super‐Resolution Imaging of Mitochondrial Cristae Dynamics

Advanced Science, EarlyView.
Regulation of molecular packing, phototoxicity, and ROS output of AIE photosensitizers is achieved through carboxylation and alkyl‐chain‐length tuning. The probe designed via this strategy enables super‐resolution visualization of inner‐mitochondrial‐membrane cristae dynamics under controlled oxidative stress, and fluorescence‐lifetime imaging of ...
Kongqi Chen, Mengjie Wang, Chuen Kam, Zhiming Wang, Qinrong Zhang, Sijie Chen   +5 more
wiley   +1 more source

Mechanically Adaptive Polyimide Interfaces for Stable High‐Voltage NCM–Sulfide All‐Solid‐State Batteries

Advanced Science, EarlyView.
A mechanically adaptive polyimide interface dynamically stabilizes single‐crystal cathodes in sulfide all‐solid‐state batteries. By integrating robust chemical coordination with viscoelastic compliance, this smart coating suppresses parasitic reactions and accommodates cyclic volume expansion.
Jiatao Wu, Wenjin Li, Rui Wang, Peng Wang, Kaiyuan Deng, Chengshuai Chang, Chuan Xie, Lei Yao, Guangliang Gary Liu   +8 more
wiley   +1 more source

Synthesis and Pharmacological Evaluation of New 3,4-Dihydroisoquinolin Derivatives Containing Heterocycle as Potential Anticonvulsant Agents

Molecules, 2016
Two novel series of 3,4-dihydroisoquinolin with heterocycle derivatives (4a–t and 9a–e) were synthesized and evaluated for their anticonvulsant activity using maximal electroshock (MES) test and pentylenetetrazole (PTZ)-induced seizure test.
Hong-Jian Zhang, Qing-Kun Shen, Chun-Mei Jin, Zhe-Shan Quan   +3 more
doaj   +1 more source

Research Progress on Neuroprotective Effects of Isoquinoline Alkaloids

Molecules, 2023
Neuronal injury and apoptosis are important causes of the occurrence and development of many neurodegenerative diseases, such as cerebral ischemia, Alzheimer’s disease, and Parkinson’s disease. Although the detailed mechanism of some diseases is unknown,
Jinhua Li, Yarong Wu, Shuze Dong, Ye Yu, Yuhao Wu, Benhan Xiang, Qin Li   +6 more
doaj   +1 more source

Atroposelective Access to π‐Conjugated 1,2‐Azaborepines Enabled by Palladium‐Catalyzed Cyclization of N‐Heterobiaryls with Alkynylboronates

Advanced Science, EarlyView.
We report a palladium‐catalyzed atroposelective cyclization of N‐heterobiaryl triflates with alkynyl boronates to access seven‐membered 1,2‐BN‐bridged biaryls with high yields and excellent enantioselectivity via a cascade DyKAT, cis‐carbopalladation, and 1,2‐migration, which expands the toolbox for axially chiral π‐conjugated boron compounds and opens
Fengya He, Zhen Wang, Haoyu Guo, Shuguang Chen, Xu Zhang, Yongjia Shang, Hui Wang   +6 more
wiley   +1 more source