Results 101 to 110 of about 7,156 (173)
ABSTRACT Berberine (BBR) is a natural isoquinoline alkaloid with antibacterial, anti‐inflammatory and pro‐angiogenic properties. This study aimed to investigate the therapeutic efficacy and underlying mechanism of a conditioned medium (CM) derived from berberine‐preconditioned bone marrow‐derived mesenchymal stem cells (BMSCs‐BBR).
Jinglei Tan, Caiqiang Chen
wiley +1 more source
The molluscicidal activity of Hammada scoparia leaf extracts and the principal alkaloids isolated from them (carnegine and N-methylisosalsoline) were tested against the mollusc gastropod, Galba truncatula, the intermediate host of Fasciola hepatica in ...
R Mezghani-Jarraya +3 more
doaj +1 more source
Cell‐Specific Expression and Cellular Compartmental Regulation in Camptothecin Biosynthesis
ABSTRACT Plant secondary metabolites such as monoterpenoid indole alkaloids (MIAs) show tightly regulated biosynthesis and accumulation in specific organelles of distinct cell types. However, the cell‐specific expression patterns of anticancer MIA camptothecin biosynthetic genes in Ophiorrhiza pumila and the regulatory mechanisms of camptothecin ...
Xiaolong Hao +12 more
wiley +1 more source
A new synthetic method of 1-substituted isoquinolines
A series of 1-substituted isoquinolines were synthesized through the nucleophilic addition reaction of Grignard reagents to isoquinolines under the activation of benzyl chloroformate and aromatization in the presence of Pd ...
Chen Guo-Ying +2 more
core
A general approach for the synthesis of 3H-pyrazolo[3,4-c]isoquinolines and thieno[3,2-c]isoquinolines is described involving the implementation of a cascade imination/intramolecular decarboxylative coupling between potassium 2-amino(hetero)benzoates and
Subhendu Bhowmik (1903357) +2 more
core +1 more source
Synthesis of Some Novel 11b-Substituted Pyrimido[6,1-a]-isoquinoline Derivatives
A series of novel 11b-substituted 1,6,7,11b-tetrahydropyrimido[6,1-a]- isoquinoline-2,4-diones and 4-thioxo-1,3,4,6,7,11b-hexahydropyrimido[6,1-a]isoquinolin-2- ones were synthesized, utilizing two alternative strategies for ring closure of ...
Atanas P. Venkov +2 more
doaj +1 more source
The number and position of methoxy substituents provide a versatile molecular toolbox for tuning the photophysics and visible‐light photocatalytic performance of heteroleptic Cu(I) photosensitizers. Earth‐abundant Cu(I) photosensitizers are promising systems for visible‐light‐driven photocatalysis, but further design guidelines are required to relate ...
Kurt J. Haseloff +6 more
wiley +1 more source
α -Cyano-o-toluonitrile is a-ethoxycarbonylated with ethyl chloroformate and 4-dimethylamino- pyridine, and cyclized to ethyl 3-amino-1-bromoisoquinoline-4-carboxylate.
LW Deady, AM Ganakas, BH Ong
core +1 more source
Palladium-catalysed enolate arylation in the synthesis of isoquinolines [PDF]
Chapter 1. Introduction Scientific background on the development of homogeneous palladium-catalysed cross coupling reactions, focusing on the α-arylation reaction of enolates and its application to the synthesis of heteroaromatic compounds. The classical
Gatland, Alice Elizabeth
core +1 more source
Synthesis of New β-enaminones of Isoquinolines with 5,5-dimethyl-cyclohexanedione
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Stoyanka Nikolova, Iliyan Ivanov
doaj +1 more source

