Results 101 to 110 of about 7,156 (173)

Berberine‐Pretreated Bone Marrow Mesenchymal Stem Cells Accelerate Skin Wound Healing in Rats With Burn Injuries

open access: yesInternational Wound Journal, Volume 23, Issue 9, September 2026.
ABSTRACT Berberine (BBR) is a natural isoquinoline alkaloid with antibacterial, anti‐inflammatory and pro‐angiogenic properties. This study aimed to investigate the therapeutic efficacy and underlying mechanism of a conditioned medium (CM) derived from berberine‐preconditioned bone marrow‐derived mesenchymal stem cells (BMSCs‐BBR).
Jinglei Tan, Caiqiang Chen
wiley   +1 more source

Molluscicidal activity of Hammada scoparia (Pomel) Iljin leaf extracts and the principal alkaloids isolated from them against Galba truncatula

open access: yesMemorias do Instituto Oswaldo Cruz, 2009
The molluscicidal activity of Hammada scoparia leaf extracts and the principal alkaloids isolated from them (carnegine and N-methylisosalsoline) were tested against the mollusc gastropod, Galba truncatula, the intermediate host of Fasciola hepatica in ...
R Mezghani-Jarraya   +3 more
doaj   +1 more source

Cell‐Specific Expression and Cellular Compartmental Regulation in Camptothecin Biosynthesis

open access: yesPlant Biotechnology Journal, Volume 24, Issue 9, Page 5114-5130, September 2026.
ABSTRACT Plant secondary metabolites such as monoterpenoid indole alkaloids (MIAs) show tightly regulated biosynthesis and accumulation in specific organelles of distinct cell types. However, the cell‐specific expression patterns of anticancer MIA camptothecin biosynthetic genes in Ophiorrhiza pumila and the regulatory mechanisms of camptothecin ...
Xiaolong Hao   +12 more
wiley   +1 more source

A new synthetic method of 1-substituted isoquinolines

open access: yes, 2006
A series of 1-substituted isoquinolines were synthesized through the nucleophilic addition reaction of Grignard reagents to isoquinolines under the activation of benzyl chloroformate and aromatization in the presence of Pd ...
Chen Guo-Ying   +2 more
core  

Synthesis of 3H‑Pyrazolo[3,4‑c]isoquinolines and Thieno[3,2‑c]isoquinolines via Cascade Imination/Intramolecular Decarboxylative Coupling

open access: yes, 2016
A general approach for the synthesis of 3H-pyrazolo[3,4-c]isoquinolines and thieno[3,2-c]isoquinolines is described involving the implementation of a cascade imination/intramolecular decarboxylative coupling between potassium 2-amino(hetero)benzoates and
Subhendu Bhowmik (1903357)   +2 more
core   +1 more source

Synthesis of Some Novel 11b-Substituted Pyrimido[6,1-a]-isoquinoline Derivatives

open access: yesMolecules, 2004
A series of novel 11b-substituted 1,6,7,11b-tetrahydropyrimido[6,1-a]- isoquinoline-2,4-diones and 4-thioxo-1,3,4,6,7,11b-hexahydropyrimido[6,1-a]isoquinolin-2- ones were synthesized, utilizing two alternative strategies for ring closure of ...
Atanas P. Venkov   +2 more
doaj   +1 more source

Number and Position of Methoxy Substituents Govern Photophysics and Visible‐Light Photocatalysis in Earth‐Abundant Cu(I) Complexes

open access: yesChemSusChem, Volume 19, Issue 16, 27 August 2026.
The number and position of methoxy substituents provide a versatile molecular toolbox for tuning the photophysics and visible‐light photocatalytic performance of heteroleptic Cu(I) photosensitizers. Earth‐abundant Cu(I) photosensitizers are promising systems for visible‐light‐driven photocatalysis, but further design guidelines are required to relate ...
Kurt J. Haseloff   +6 more
wiley   +1 more source

Ethoxycarbonylation of α-Cyano-o-toluonitrile and Cyclization to Isoquinolines and Pyrimido[4,5-c]isoquinolines

open access: yes, 1989
α -Cyano-o-toluonitrile is a-ethoxycarbonylated with ethyl chloroformate and 4-dimethylamino- pyridine, and cyclized to ethyl 3-amino-1-bromoisoquinoline-4-carboxylate.
LW Deady, AM Ganakas, BH Ong
core   +1 more source

Palladium-catalysed enolate arylation in the synthesis of isoquinolines [PDF]

open access: yes, 2014
Chapter 1. Introduction Scientific background on the development of homogeneous palladium-catalysed cross coupling reactions, focusing on the α-arylation reaction of enolates and its application to the synthesis of heteroaromatic compounds. The classical
Gatland, Alice Elizabeth
core   +1 more source

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