Results 121 to 130 of about 29,358 (323)
Antiplasmodial ealapasamines A-C,'mixed' naphthylisoquinoline dimers from the Central African liana Ancistrocladus ealaensis [PDF]
, 2017 Three unusual heterodimeric naphthylisoquinoline alkaloids, named ealapasamines A-C (1-3), were isolated from the leaves of the tropical plant Ancistrocladus ealaensis J. Léonard.
Bringmann, Gerhard +5 more
core +1 more source
Salsolinol: an Unintelligible and Double-Faced Molecule—Lessons Learned from In Vivo and In Vitro Experiments [PDF]
, 2017 Salsolinol (1-methyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline) is a tetrahydroisoquinoline derivative whose presence in humans was first detected in the urine of Parkinsonian patients on l-DOPA (l-dihydroxyphenylalanine) medication.
Bugajski, Andrzej +3 more
core +2 more sources
Advances in the Preparation of Fluorinated Isoquinolines: A Decade of Progress
Journal of Chemistry, 2017 Heterocyclic molecules incorporating fluorinated isoquinoline components are found in many medicinally and agriculturally important bioactive products as well as industrially impactful materials.
Joseph C. Sloop
doaj +1 more source
Archiv der Pharmazie, Volume 358, Issue 8, August 2025.The ubiquitin‐specific protease 7 (USP7) catalyzes the removal of ubiquitin and protects substrate proteins from degradation. USP7 causes structural changes upon ubiquitin binding, making it particularly suitable for use in covalent targeting approaches. The development, synthesis, and biophysical screening of a series of mildly electrophilic compounds
Larissa N. Ernst +11 more
wiley +1 more source
“Estudio de la formación de pirrolo[2,1-a]3,4- dihidroisoquinolinas a través del uso de energía alternativa de radiación de microondas, partiendo de la síntesis de chalconas intermediarias” [PDF]
, 2014 En el presente trabajo de investigación se describe la síntesis de derivados de pirrolo[2,1- a]isoquinolinas. La parte medular de este proceso de síntesis involucra reacciones de acoplamiento C-C tipo Heck, a través de procesos de catálisis mediadas con ...
Corona Becerril, David +1 more
core
Advances in Ligand‐Driven Pd‐Catalyzed C─H Functionalizations: Recent Insights and Updates
ChemCatChem, Volume 17, Issue 15, August 7, 2025.The most significant advances in ligand‐driven Pd‐catalyzed organic synthesis over the past two years are presented. Processes involving C─H activation of substrates, avoiding their prefunctionalization are illustrated. Both the activity and selectivity of the catalyst depend on the design of the ligands (pyridones, pyridines, amino acids, phosphines ...
Jesús Moradell +3 more
wiley +1 more source
European Journal of Lipid Science and Technology, Volume 127, Issue 8, August 2025.Biocompatible and biodegradable liposomes were developed to encapsulate naringenin (N) and berberine (B), enhancing their stability and bioavailability. Their effects on thermogenesis and browning in 3T3‐L1 preadipocyte cells compared to their free forms were investigated.
Elif Didem Örs Demet +7 more
wiley +1 more source
Beckmann Rearrangement in Liquid Sulfur Dioxide. IV. Syntheses of 1-Methyl-3,4-dihydro-isoquinoline and 9-Phenyl-phenanthridine [PDF]
, 1958 Ritsuro Tada +2 more
openalex +1 more source
Food Science &Nutrition, Volume 13, Issue 8, August 2025.The positive influence of berberine on the nervous system can be attributed to its diverse effects on multiple targets. The effects of berberine include its antioxidant, anti‐apoptotic, anti‐necroptotic, and anti‐inflammatory properties, as well as its ability to induce autophagy.
Xiaolan Wang +5 more
wiley +1 more source
CNS Neuroscience &Therapeutics, Volume 31, Issue 8, August 2025.Plant‐derived compounds such as polyphenols, flavonoids, alkaloids, and terpenoids exhibit neuroprotective, antioxidant, and anti‐inflammatory activities in Parkinson's disease models. Unlike levodopa, they provide disease‐modifying benefits by targeting α‐synuclein aggregation, mitochondrial dysfunction, and neuroinflammation.
Emre Aktaş +2 more
wiley +1 more source