Results 121 to 130 of about 17,105 (265)

From MS1 to Structure: A Van Krevelen–DBE–Aromaticity‐Based Framework for Annotating Specialized Metabolites via High‐Resolution Mass Spectrometry

Rapid Communications in Mass Spectrometry, Volume 39, Issue 24, 30 December 2025.
ABSTRACT Rationale Classifying specialized metabolites in untargeted metabolomics remains a major challenge, particularly when relying solely on high‐resolution mass spectrometry (HRMS) data at the MS1 level. Traditional approaches using Van Krevelen diagrams often lack sufficient resolution to distinguish structurally similar metabolite classes ...
Nerilson M. Lima, Luana A. Pereira, Lucas S. Tironi, Matheus P. G. do Carmo, Milbya L. Costa, Renato A. Oliveira, Salva Asghar, Vinicius Fortes da Silva   +7 more
wiley   +1 more source

Synthesis and Reactions of 1‐Amino‐5‐morpholin‐4‐yl‐6,7,8,9‐tetrahydrothieno[2,3‐c]isoquinoline [PDF]

, 2011
Remon M. Zaki, Shaban M. Radwan, Adel M. Kamal El‐Dean   +2 more
openalex   +1 more source

Pd(II)/N,N′-Disulfonyl bisimidazoline-catalyzed asymmetric arylation of isoquinoline-1,3,4-trione-derived ketimines

, 2023
An‐Qi Miao, Yuxin Wang, Linlin Xu, Wen‐Juan Hao, Shu‐Jiang Tu, Jinpeng Zhang, Bo Jiang   +6 more
openalex   +1 more source

Novel N-Linked Isoquinoline Amides as LRRK2 Inhibitors for Treating Parkinson’s Disease [PDF]

, 2022
Ram W. Sabnis
openalex   +1 more source

Determination of Cytotoxic Activity of Selected Isoquinoline Alkaloids and Plant Extracts Obtained from Various Parts of Mahonia aquifolium Collected in Various Vegetation Seasons

, 2021
Tomasz Tuzimski, Anna Petruczynik, Barbara Kaproń, Anna Makuch‐Kocka, Małgorzata Szultka‐Młyńska, Justyna Misiurek, Grażyna Szymczak, Bogusław Buszewski   +7 more
openalex   +1 more source

Concise total syntheses of (–)-jorunnamycin A and (–)-jorumycin enabled by asymmetric catalysis [PDF]

, 2019
The bis-tetrahydroisoquinoline (bis-THIQ) natural products have been studied intensively over the past four decades for their exceptionally potent anticancer activity, in addition to strong gram-positive and -negative antibiotic character.
Allan, Kevin M., Conklin, Dylan, Gilmore, Christopher D., Glibstrup, Emil, Grünanger, Christian U., Haley, Christopher K., Klatte, Max, Lapointe, Guillaume, McDermott, Martina S. J., Negoro, Kenji, Ngamnithiporn, Aurapat, Pototschnig, Gerit M., Slamon, Dennis J., Stoltz, Brian M., Tadross, Pamela M., Virgil, Scott C., Welin, Eric R.   +16 more
core  

Chiral N-acyliminium ions as new tools in the asymmetric synthesis of CNS-active compounds [PDF]

, 1994
Beutler, Comins, Gray, Hellmann, Irie, K.Th. Wanner, Kiguchi, Wanner, Wanner, Wong   +9 more
core   +1 more source

Enantioselective palladium(0)-catalyzed C-H arylation strategy for chiral heterocycles [PDF]

, 2017
Transition-metal-catalyzed C-H functionalizations have emerged as complementary and powerful tools to access molecular complexity from widely available starting materials.
Cramer, Nicolai, Saget, Tanguy
core  

Synthesis of Fused Systems in the Isoquinoline Series: Oxazolo- and Pyrrolo[3,2-c]isoquinolines

, 2000
Georges Dupas, Jean‐François Brière, G. QUEGUINER, Jean Bourguignon   +3 more
openalex   +1 more source

Brønsted acid catalyzed enantioselective inter and intramolecular α-amidoalkylation reactions in the synthesis of isoquinoline derivatives

, 2016
Eider Aranzamendi Uruburu, Nuria Sotomayor, Esther Lete   +2 more
openalex   +1 more source