Рациональная фармакотерапия в кардиологии, 2016 Aim. In multicentral program PRIORITY to estimate the efficacy of antianginal therapy after switching patients with stable angina from therapy with short-acting nitrates or isosorbide dinitrate in long-term acting formulation to therapy with isosorbide-5-
Yu. A. Karpov
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Use of Hydralazine‐Isosorbide Dinitrate Combination in African American and Other Race/Ethnic Group Patients With Heart Failure and Reduced Left Ventricular Ejection Fraction [PDF]
, 2013 Background: Hydralazine‐isosorbide dinitrate (H‐ISDN) therapy is recommended for African American patients with moderate to severe heart failure with reduced ejection fraction (
Bhatt, Deepak L. +8 more
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Vasodilator Therapy: Nitrates and Nicorandil. [PDF]
, 2016 Nitrates have been used to treat symptoms of chronic stable angina for over 135 years. These drugs are known to activate nitric oxide (NO)-cyclic guanosine-3',-5'-monophasphate (cGMP) signaling pathways underlying vascular smooth muscle cell relaxation ...
Kaski, JC, Tarkin, JM
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Development composite polymer matrix tablets with a preset time of isosorbide dinitrate release by the method of mathematical modeling [PDF]
, 2019 Изучена кинетика высвобождения изосорбида динитрата из покрытых и непокрытых гранул диаметром 0,5-0,8 мм и 0,8-1,25 мм, используемых для приготовления матричных таблеток. Проведен статистический анализ полученных результатов.
Кондратов, Сергей Алексеевич +3 more
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Medisur, 2005 Fundament: Oral antihypertensive drugs are lacking in our environment at present in tog hypertensive urgencies, that is why new therapeutic alternatives are necessary to treat this medical problem.
Brandy Viera Valdés
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Nitrates in the treatment of patients with coronary artery disease: focus on isosorbide dinitrate
Медицинский совет, 2015 The article tells about the pharmacology of nitrates and their place in comprehensive treatment of coronary artery disease. The mechanisms of action of organic nitrates, specifically the short-acting metered dose spray isosorbide dinitrate (ID), are ...
V. P. Lupanov
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Response of conductance and resistance coronary vessels to scalar concentrations of acetylcholine: Assessment with quantitative angiography and intracoronary Doppler echography in 29 patients with coronary artery disease [PDF]
, 1994 Abnormal vasoreactivity of the large conductance arteries has been observed in the presence of impaired endothelial function. More recently, experimental and clinical reports have shown that in early coronary atherosclerosis the impairment of the ...
Feyter, P.J. (Pim) de +5 more
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Frontiers in Pharmacology, 2019 The survival rate of cardiac arrest patients is less than 10%; therefore, development of a therapeutic strategy that improves their prognosis is necessary. Herein, we searched data collected from medical facilities throughout Japan for drugs that improve
Yoshito Zamami +20 more
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Increased baseline ECG R-R dispersion predicts improvement in systolic function after atrial fibrillation ablation. [PDF]
, 2019 BackgroundAtrial fibrillation (AF) is associated with left ventricular (LV) systolic dysfunction which may improve after AF ablation. We hypothesised that increased ventricular irregularity, as measured by R-R dispersion on the baseline ECG, would ...
Buch, Eric +7 more
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Fast Dissolving Sublingual Strips: A Novel Approach for the Delivery of Isosorbide Dinitrate [PDF]
Pharmaceutical Sciences, 2019 Background: Isosorbide dinitrate (ISDN) is used for treating the angina attacks. In addition, oral ISDN is available in immediate and sustained release formulations and the bioavailability of ISDN is about 20-25% when taken orally.
Marzieh Fathei +6 more
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