Results 21 to 30 of about 4,437 (171)

Fast Dissolving Sublingual Strips: A Novel Approach for the Delivery of Isosorbide Dinitrate [PDF]

Pharmaceutical Sciences, 2019
Background: Isosorbide dinitrate (ISDN) is used for treating the angina attacks. In addition, oral ISDN is available in immediate and sustained release formulations and the bioavailability of ISDN is about 20-25% when taken orally.
Marzieh Fathei, Mitra Alami-milani, Sara Salatin, Sharahm Sattari, Hassan Montazam, Farhad Fekrat, Mitra Jelvehgari   +6 more
doaj   +1 more source

Responsive nitric oxide‐releasing antibacterial materials for biofilm‐associated infections: Mechanisms, design strategies, and applications

Responsive Materials, EarlyView.
This review summarizes the recent progress in responsive NO‐releasing materials and their applications in biofilm‐associated infectious diseases. The design principles and response mechanisms are given to provide inspiration toward the future development of multi‐responsive NO‐releasing materials.
Wenyue Sun, Meiqi Li, Di Nan, Jiaqi Zhao, Yu Chen, Yao Gao, Shichen Zhang, Kirsten L. Van Landuyt, Manlin Qi   +8 more
wiley   +1 more source

Systemic medications associate with surgically treated cataract among adults over 50 years in Finland

Acta Ophthalmologica, EarlyView.
Abstract Purpose To identify associations between systemic drugs and cataract surgery in Finland. Methods A historic cohort study based on administrative data. Endpoint event was cataract surgery. Use of drugs in question was based on redeemed prescriptions and consisted of 156 drugs.
Antti Riikonen, Jari Haukka, Tuomas Lilius, Sirpa Loukovaara   +3 more
wiley   +1 more source

Safety and Efficacy of Endoluminal Vasodilators on the Prevention of Vasospasm in Deep Inferior Epigastric Perforator Flap Breast Reconstruction: A Prospective Controlled Study

Journal of Reconstructive Microsurgery Open, 2016
Background The spasm of the internal mammary artery (IMA) and inferior epigastric pedicle (IEP) is critical in deep inferior epigastric perforator (DIEP) flap breast reconstruction.
Barbara Hersant, Romain Bosc, Mounia SidAhmed-Mezi, Mathieu Kerneis, Jean-Paul Meningaud   +4 more
doaj   +1 more source

Drug-Induced Hemolysis in G6PD Deficiency: an Unusual Presentation of a Common Clinical Condition

Acta Medica, 2020
Glucose-6-phosphate dehydrogenase (G6PD) deficiency can present a diagnostic dilemma owing to the varying degrees of disease severity and the wide range of precipitating factors.
Anudeep Padakanti, Ashok Shenoy, Ashwin Kamath, Mahabala Chakrapani   +3 more
doaj   +1 more source

A Radioresistant‐Tumor‐Targeted Nanoparticle for X‐Ray‐Controlled Nitric Oxide Release to Potentiate Radiotherapy

Advanced Science, Volume 13, Issue 40, 17 July 2026.
The PBTN targets GRP78 and, upon X‐ray irradiation, generates ONOO− to induce immunogenic cell death, thereby activating CD8+ T cells and establishing a systemic antitumor immune response. ABSTRACT Nitric oxide (NO) treated radioresistant tumors by relieving hypoxia and blocking DNA repair, but its nonselective toxicity has precluded therapeutic use ...
Wanze Zhang, Xiaoyan Yin, Ting Wang, Hongfu Zhao, Zhipeng Zhao, Jinbao Wang, Cheng Tao, Xuanchu Ge, Yanze Li, Linlin Liu, Fuxin Xue   +10 more
wiley   +1 more source

THE CHOICE OF NITRATE THERAPY IN PATIENTS WITH STABLE ANGINA: COMPARATIVE STUDY OF ISOSORBIDE DINITRATE (IN USUAL TABLETS) WITH ISOSORBIDE-5-MONONITRATE (IN VARIOUS PRESENTATIONS)

Рациональная фармакотерапия в кардиологии, 2016
Aim. To study efficacy and tolerability of isosorbide-5-mononitrate (IMN) in various presentations in comparison with isosorbide dinitrate (IDN) in usual tablets in patients with stable angina.Material and Methods.
V. A. Egoro, E. V. Shilova, S. Y. Martsevich   +2 more
doaj   +1 more source

Isosorbide dinitrate as an effective adjunct therapy for acute urinary retention: A randomized controlled trial

BJUI Compass, Volume 7, Issue 7, July 2026.
Abstract Objective To evaluate the synergistic effect and safety of sublingual isosorbide dinitrate (ISDN) to facilitate successful voiding trial after catheterization for acute urinary retention (AUR) secondary to benign prostatic hyperplasia (BPH). Material and methods In this randomized clinical trial, male patients aged ≥ 50 years presenting with ...
Salman Soltani, Hamid Reza Ghorbani, Mahmoud Tavakkoli, Fatemeh Sadabadi, Seyyed Parham Ahmadi, Farid Zeinali   +5 more
wiley   +1 more source

Combined isosorbide dinitrate and ibuprofen as a novel therapy for muscular dystrophies: evidence from Phase I studies in healthy volunteers

Drug Design, Development and Therapy, 2014
Maria Vittoria Cossu,1 Dario Cattaneo,1 Serena Fucile,1 Paolo Pellegrino,1 Sara Baldelli,1 Valeria Cozzi,1 Amedeo Capetti,2 Emilio Clementi1,3 1Unit of Clinical Pharmacology, Consiglio Nazionale delle Ricerche Institute of Neuroscience, Department of ...
Cossu MV, Cattaneo D, Fucile S, Pellegrino P, Baldelli S, Cozzi V, Capetti A, Clementi E   +7 more
doaj  

Trajectories of Treatment Disruption for Chronic Outpatient Medications for U.S. Veterans During Drug Shortages

Pharmacoepidemiology and Drug Safety, Volume 35, Issue 6, June 2026.
ABSTRACT Introduction Although drug shortages for outpatient chronic conditions commonly occur, population‐level data on how they impact patients' ability to refill prescriptions is scarce. We sought to identify distinct patterns of refill adherence following drug shortages and patient‐ and prescription‐level factors associated with adherence ...
Katie J. Suda, Xinhua Zhao, Sherrie L. Aspinall, Yaming Li, Katherine Callaway Kim, Francesca E. Cunningham, Taylor L. Boyer, Tate W. Miner, Clara Kima, Walid F. Gellad, Peter A. Glassman, Chester B. Good, Felicia Skelton, Mina Tadrous, Carolyn T. Thorpe   +14 more
wiley   +1 more source