Results 31 to 40 of about 4,437 (171)

Involvement of Guanylate Cyclase and K+ Channels in Relaxation Evoked by Ferulate Nitrate in Rat Aorta Artery

Journal of Pharmacological Sciences, 2012
Vasorelaxant properties of N-2-(ferulamidoethyl)-nitrate (ferulate nitrate, FLNT), a newly synthesized nitrate, were compared with those of isosorbide dinitrate, nicorandil, nitroglycerin, and 8-bromoguanosine 3,5-cyclic monophosphate (8-Br-cGMP) in rat ...
Zhan-Qing Wang, Jing-Feng Xu, Jin-Ping Wang, Wei-Juan Zhao, Ming Zeng   +4 more
doaj   +1 more source

Impairment by Hypoxia or Hypoxia/Reoxygenation of Nitric Oxide–Mediated Relaxation in Isolated Monkey Coronary Artery: the Role of Intracellular Superoxide

Journal of Pharmacological Sciences, 2011
.: To investigate the effect of hypoxia or hypoxia/reoxygenation on vascular smooth muscle function, mechanical response of monkey coronary artery without endothelium was studied under normoxia, hypoxia, and hypoxia/reoxygenation.
Masashi Tawa, Kohei Yamamizu, Ayman Geddawy, Takashi Shimosato, Takeshi Imamura, Kazuhide Ayajiki, Tomio Okamura   +6 more
doaj   +1 more source

Vertebral Artery Occlusion With Ipsilateral Weakness Due to Ischemic Stroke at the Medulla–Cervical Spinal Cord Junction: A Case Report

Clinical Case Reports, Volume 14, Issue 5, May 2026.
ABSTRACT Posterior circulation strokes can present with diverse neurological deficits, some of which challenge conventional localization principles. We report a case of a 74‐year‐old male with a history of prior right medullary infarct who presented with recurrent symptoms and was found to have a new medullary acute ischemic stroke in the setting of ...
Peter Felton, Yugant Khand, Mohammad Gharavi, Ram Saha   +3 more
wiley   +1 more source

Medical therapy following hospitalization for heart failure with reduced ejection fraction and association with discharge to long-term care: a cross-sectional analysis of the REasons for Geographic And Racial Differences in Stroke (REGARDS) population

BMC Cardiovascular Disorders, 2017
Background Less intensive treatment for heart failure with reduced ejection fraction (HFrEF) may be appropriate for patients in long-term care settings because of limited life expectancy, frailty, comorbidities, and emphasis on quality of life.
Emily B. Levitan, Melissa K. Van Dyke, Ligong Chen, Raegan W. Durant, Todd M. Brown, J. David Rhodes, Olusola Olubowale, Oluwole Muyiwa Adegbala, Meredith L. Kilgore, Justin Blackburn, Karen C. Albright, Monika M. Safford   +11 more
doaj   +1 more source

Conducting Medication Reviews: A Comparative Study Between ChatGPT‐4 and Healthcare Professionals

Journal of the American Geriatrics Society, Volume 74, Issue 5, Page 1378-1385, May 2026.
ABSTRACT Background The increasing prevalence of patients with hyperpolypharmacy (> 10 medications) has made medication reviews increasingly complex. ChatGPT‐4‐Turbo (ChatGPT), a large language model, has demonstrated potential in healthcare applications and could potentially support medication reviews.
Simone M. K. ten Hoope, Sabrina Marongiu, Carl E. H. Siegert, Eibert R. Heerdink, Marjo J. A. Janssen, Fatma Karapinar‐Çarkit   +5 more
wiley   +1 more source

Therapeutic Gases in Biomedicine: Updates on Nitric Oxide and Beyond

Advanced Science, Volume 13, Issue 23, 23 April 2026.
Therapeutic gases, including NO, CO, H2S, H2, CO2, O2, and Xe, play vital roles in cellular signaling and repair. This review highlights the emerging carriers and delivery systems that enable controlled, localized gas release for diagnostic and therapeutic applications.
Syed Muntazir Andrabi, Navatha Shree Sharma, Imran Ibn Gani Rather, S. M. Shatil Shahriar, Jingwei Xie   +4 more
wiley   +1 more source

Comparison of short head-up tilt test with conventional protocol after omission of nonmedicated phase in children and young adults

Advanced Biomedical Research, 2016
Background: Syncope is an important and common clinical condition, and the neurally mediated syncope is the most frequent type of syncope. Tilt testing is considered as a first-line diagnostic test.
Bahar Dehghan, Mohammad Reza Sabri
doaj   +1 more source

Multisystem Sarcoidosis Presenting With Hypercalcemia, Lytic Bone Lesion, and Mesenteric Panniculitis in Chronic Kidney Disease

Clinical Case Reports, Volume 14, Issue 4, April 2026.
The clinical photograph shows bilateral leg swelling with right‐sided predominance and cutaneous changes. CT images (A–C) demonstrate abdominal and retroperitoneal lymphadenopathy, and image D shows a hypodense lytic spinal lesion, suggesting multifocal disease involving the abdomen, retroperitoneum, and spine.
Aishwarya Holi, Karuna Rayamajhi, Satya Rijal, Niket Shah, Aaron Sousa, Gina Chacon Osorio   +5 more
wiley   +1 more source

Possibilities of nicorandil for coronary insufficiency correction in patients with ischemic heart disease and diabetes mellitus type 2

Медицинский совет, 2019
Cardiovascular complications of type 2 diabetes mellitus (T2DM) are now a global health problem, due to their main cause of mortality of these patients. Ischemic heart disease (IHD) among all cardiovascular diseases occupies a leading position.
Zh. M. Sizova, V. L. Zakharova, N. V. Kozlova   +2 more
doaj   +1 more source

Multi‐View Biomedical Foundation Models for Molecule‐Target and Property Prediction

Advanced Science, Volume 13, Issue 14, 9 March 2026.
Molecular foundation models can provide accurate predictions for a large set of downstream tasks. We develop MMELON, an approach that integrates pre‐trained graph, image, and text foundation models and validate our multi‐view model on over 120 tasks, including GPCR binding.
Parthasarathy Suryanarayanan, Yunguang Qiu, Shreyans Sethi, Diwakar Mahajan, Hongyang Li, Yuxin Yang, Elif Eyigoz, Aldo Guzmán‐Sáenz, Daniel E. Platt, Timothy H. Rumbell, Kenney Ng, Sanjoy Dey, Myson Burch, Bum Chul Kwon, Pablo Meyer, Feixiong Cheng, Jianying Hu, Joseph A. Morrone   +17 more
wiley   +1 more source