Results 151 to 160 of about 254,991 (338)

T1WI‐SWI Dual Modal Magnetic Resonance Nanoprobes for Accurate Diagnosis of Early Stage Alzheimer's Disease

Advanced Science, EarlyView.
We developed a smart MRI nanoprobe targeting BACE1 and Aβ plaques. It crosses the blood‐brain barrier. Upon encountering BACE1, the probe is cleaved, enabling T1WI imaging detection. Subsequent reaction with ONOO− induces probe aggregation, enhancing magnetic susceptibility for sensitive SWI imaging of Aβ plaques.
Minghua Li, Aijun Shen, Xiaolong Gao, Chao Lin, Zongliang Huang, Qi Lv, Junjun Tang, Xiaolong Ma, Jiong Ni, Ju Tian, Jiaqi Wu, Xiaowen Xu, Wei Wang, Peijun Wang   +13 more
wiley   +1 more source

Histological study of hepatoprotective aspect of indigo and its isolated isothiocyanate compound against N-Nitrosopyrrolidine in toxicated mice

, 2018
Rashmi Singh, Veena Sharma, Shatruhan Sharma   +2 more
openalex   +1 more source

RETRACTED: Phenethyl isothiocyanate attenuates diabetic nephropathy via modulation of glycative/oxidative/inflammatory signaling in diabetic rats

, 2021
Nada H. Eisa, Ahmed E. Khodir, Mohamed El‐Sherbiny, Nehal M. Elsherbiny, Eman Said   +4 more
openalex   +1 more source

Targeting the SOX9/TIMP1 Axis with iRGD‐Conjugated Nanoplatform Enhances Dendritic Cell Function and Photodynamic Immunotherapy in Gastric Cancer

Advanced Science, EarlyView.
This study identifies the SOX9/TIMP1 axis as a key regulator of immune evasion in gastric cancer. iRGD‐conjugated nanoparticles co‐delivering si‐SOX9, Ce6, and L‐Arg are developed to synergize with photodynamic therapy. The nanoplatform suppresses tumor growth, promotes dendritic cell maturation, and enhances CD8+ T‐cell activation, offering a ...
Banghua Zhong, Yijie Zhang, Honghu Wang, Lili Guo   +3 more
wiley   +1 more source

New Methods and Reagents in Organic Synthesis. 54. Lithium Trimethylsilylydiazomethane: A New Synthon for the Preparation of 1-Substituted 5-Alkylthio-1,2,3-triazoles from Isothiocyanates

, 1985
Toyohiko Aoyama, Mototsugu Kabeya, Takayuki Shioiri   +2 more
openalex   +1 more source

Synergistic Anti‐Cancer Therapy Through Ultrasound‐Induced Piezocatalytic Therapy and Tumor Treatment Fields

Advanced Science, EarlyView.
A novel, wearable anti‐cancer platform synergistically combines tumor treating fields (TTFs) and piezocatalytic therapy (PCT) via ultrasound‐activated, lead‐free piezocomposites. This strategy efficiently suppresses tumor growth, modulates the immune microenvironment, and demonstrates strong therapeutic synergy in both mouse model of subcutaneous tumor
Jing Jin, Haoyue Xue, Keliang Chen, Yonglin Su, Xin Hu, Xiaolin Hu, Xing Huang, Laiming Jiang, Jiagang Wu, Xingchen Peng   +9 more
wiley   +1 more source

Supplementary Table 4 from Effects of Phenylethyl Isothiocyanate on Early Molecular Events in <i>N</i>-Nitrosomethylbenzylamine–Induced Cytotoxicity in Rat Esophagus

, 2023
Rashmeet K. Reen, Alan A. Dombkowski, Laura A. Kresty, Daniela Cukovic, Jennifer M. Mele, Sridevi Salagrama, Ronald Nines, Gary D. Stoner   +7 more
openalex   +1 more source

Engineered Multifunctional Hydrogel Delivering Novel CBX7 Inhibitor Modulates Cuproptosis Via Liquid–Liquid Phase Separation to Restore Cardiac Function in Aged Myocardial Infarction

Advanced Science, EarlyView.
An age‐adapted therapy pairs δ‐Amyrenone, a CBX7 inhibitor, with an alginate hydrogel (CSAδ) to rescue infarcted elderly hearts. CSAδ disrupts CBX7–ATP7A liquid–liquid phase separation, restores ATP7A trafficking and copper efflux, suppresses cuproptosis, supplies oxygen, scavenges ROS, promotes M2 polarization, supports angiogenesis, and enhances ...
Jun Liu, Peng Qu, Jiao Shi, Tingting Liang, Yao Gu, Xue Li, Cui Ma, Danyang Zhao, Feila Liu, Qi Liang, Panke Cheng, Qian Lei   +11 more
wiley   +1 more source

Effects of Food Ingredients on Inactivation of Escherichia coli by Hydrostatic Pressure Treatment with the Addition of Allyl Isothiocyanate.

, 2001
Tetsuro Ogawa, Atsushi Nakatani, Hajime Matsuzaki, Seiichiro Isobe, Kenji Isshiki   +4 more
openalex   +2 more sources

isoThiocyanates. XXXV. Miscellaneous isoThiocyanate Glucoside Acetates. [PDF]

Acta Chemica Scandinavica, 1959
Anders Kjær, S. Laland, I. Smith-Kielland, R. Sömme, Einar Stenhagen, H. Palmstierna   +5 more
openaire   +1 more source