Permeation Enhancer‐based Ionogel Shows Remarkable Potential for Oral Insulin Delivery
This study proposes a novel formulation of decanoate in an ionic liquid inspired drug delivery system. The formulation demonstrates ideal physicochemical and material properties for oral peptide delivery. Findings indicate that choline decanoate (1:2 molar ratio) forms a viscoelastic gel that enables high oral bioavailability of insulin in rats ...
Konstantinos Raptis+6 more
wiley +1 more source
isoThiocyanates. XXXIV. The Absolute Configuration of (-)-5-Vinyl-2-oxazolidinethione (Goitrin) and its Glucosidic Progenitor (Progoitrin). [PDF]
Anders Kjær+5 more
openalex +1 more source
isoThiocyanates. XXIV. (+)-, (-)-, and (+-)-alpha-Methylbenzyl isoThiocyanate. [PDF]
Anders Kjær+4 more
openaire +2 more sources
This review highlights recent progress in nanocarriers targeting pattern recognition receptors (PRRs), including Toll‐like and NOD‐like receptors, for enhancing the treatment of bacterial sepsis and related complications. These nanomedicines deliver antibiotics and anti‐inflammatory agents while modulating immune responses.
Eman A. Ismail+3 more
wiley +1 more source
Phyllotreta species (Coleoptera, Chrysomelidae, Halticinae) rank among the most important horticultural pests in the Northern Hemisphere. Leaf damage caused by flea beetles upsets the water balance, blocks plant growth and sometimes causes a high level ...
É. Csonka, M. Tóth
doaj +1 more source
Inhibitory effect of benzyl isothiocyanate on proliferation in vitro of human glioma cells.
Malignant glioma, also known as brain cancer, is the most common intracranial tumor, having an extremely high mortality and recurrence rate. The survival rate of the affected patients is very low and treatment is difficult.
Yu Zhu+4 more
semanticscholar +1 more source
Immunosuppressive Formulations for Immunological Defense against Traumatic Brain Injury
A novel subcutaneous formulation combining alpha‐ketoglutarate, glycolysis inhibitor PFK15, and a myelin peptide reduces inflammation in a mouse TBI model. This formulation promotes regulatory immune cells, enhances autophagy, and improves motor function, suggesting its potential as a prophylactic immunosuppressive therapy to mitigate TBI‐induced ...
Kelly Lintecum+28 more
wiley +1 more source
Biofumigation: An alternative strategy for the control of plant parasitic nematodes
Plant-parasitic nematodes wreak havoc on the yield and quality of crops worldwide. Damage from these pests is estimated to exceed US$100 billion annually but is likely higher due to misdiagnosis.
Rebecca Jean Barnes BRENNAN+3 more
doaj
isoThiocyanates. XXXVI. (+)-4-Methyl-2-oxazolidinethione, the Enzymic Hydrolysis Product of a Glucoside (Glucosisymbrin) in Seeds of Sisymbriura austriacum Jacq. [PDF]
Anders Kjær+3 more
openalex +1 more source